Does non-invasive prenatal genetic testing require fasting? Prenatal testing can be described as an insurance for pregnant women and fetuses, while non-invasive prenatal genetic testing begins with genes. Noninvasive prenatal genetic testing mainly screens three common chromosomal diseases. The following is whether non-invasive prenatal genetic testing requires fasting.
Does non-invasive prenatal genetic testing require fasting? 1 What is non-invasive prenatal genetic testing?
Non-invasive prenatal genetic testing is to collect pregnant women's peripheral blood (5ml), extract free DNA, and obtain the risk of fetal chromosome aneuploidy (2 1- trisomy, also known as Down's syndrome, 18- trisomy and 13- trisomy) by using the new generation high-throughput sequencing technology combined with biological information analysis. The best detection time of this method is the first and second trimester of pregnancy, and it has the characteristics of non-invasive sampling, no risk of abortion, high sensitivity and high accuracy.
application area
Prenatal detection of chromosome aneuploidy diseases;
As a reference for the results of karyotype analysis;
As a remedial detection method for cell culture failure in karyotype analysis;
To provide a new detection method for pregnant women who do not accept or miss the invasive prenatal diagnosis.
Adapt to the crowd
1, all pregnant women who wish to exclude fetal chromosomal aneuploidy;
2. Serum screening of high-risk pregnant women in early and middle pregnancy;
3. One of the spouses is a patient with chromosomal diseases, or a pregnant woman who has been pregnant or given birth to a child with chromosomal diseases;
4. Pregnant women with unexplained spontaneous abortion, teratoma, stillbirth or stillbirth;
5. Abnormal fetal ultrasound examination results (NT, bridge height);
6. One of the couples has a history of exposure to teratogenic substances.
test method
Non-invasive prenatal blood sampling is the same as routine venous blood sampling, and 5 mL venous blood is collected for testing. You don't need an empty stomach to collect blood, and you don't need to check in advance, as long as you have a normal diet and a regular schedule.
After blood collection, the test results can be obtained through laboratory testing and bioinformatics data analysis. After receiving the notice, please go to the sampling hospital to receive the test report, and the doctor will explain the report results and genetic counseling for you.
Now I believe everyone knows something about non-invasive prenatal testing. Non-invasive prenatal genetic testing does not require fasting blood collection, as long as there are no other special conditions in the body as usual, this test can be carried out. Mothers who need this test can go to the hospital to find a doctor to learn more. Finally, I wish you all good health and happiness.
Does non-invasive prenatal genetic testing require fasting? When will non-invasive prenatal genetic testing be done?
According to the guidelines of the Health Planning Commission, the time for non-invasive prenatal genetic testing is 12 weeks-pregnancy (22 weeks +6 days). If the pregnancy time has exceeded the upper limit (gestational age >); 22 weeks +6 days), the detection risk increases; Too small (gestational age
What items can non-invasive prenatal genetic testing do?
Non-invasive gene detection can be used to detect whether the fetus has abnormal chromosome number. Humans have 23 pairs of chromosomes. One more or one less will cause physical abnormality, which is abnormal chromosome number.
However, because this method needs data accumulation, three chromosome diseases are applied in clinical detection at this stage: 2 1- trisomy, 18- trisomy, 13- trisomy, etc. , that is, there is one more chromosome 2 1, 18 or 13. 2 1- trisomy syndrome is familiar and the most common. 18- trisomy syndrome and 13- trisomy syndrome are also accompanied by mental retardation and physical deformity.
Does non-invasive prenatal genetic testing require fasting?
To do non-invasive DNA prenatal testing, it is necessary to collect the peripheral venous blood of pregnant women first. Is it necessary to draw blood on an empty stomach for noninvasive DNA? There is no need for fasting, and normal diet will not affect the test results. Han Jin, Department of Prenatal Diagnosis, Guangzhou Women and Children Medical Center, introduced that this technology is to detect a small amount of fetal DNA in pregnant women's blood through medical means, which is different from the serological markers of pregnant women found in similar screening in the past.
In addition, if blood collection also involves routine blood tests such as liver function, blood sugar and blood lipid, it is suggested to discuss with doctors whether it is necessary to carry out non-invasive DNA prenatal testing alone or simultaneously.
Does non-invasive prenatal genetic testing require fasting? 3 What is non-invasive prenatal genetic testing?
In fact, non-invasive prenatal genetic testing is very popular in the early stage. Non-invasive prenatal genetic testing is mainly through collecting maternal peripheral blood (5ml), extracting free DNA, using the new generation high-throughput sequencing technology, and combining with the analysis of biological information, it is concluded that the fetus has chromosome aneuploidy (2 1- trisomy, also known as Down syndrome, 18- trisomy, 13- trisomy). Because non-invasive prenatal genetic testing is aimed at genetic testing.
So the accuracy is very high. In some aspects, non-invasive prenatal genetic testing is more beneficial than routine prenatal testing. Moreover, non-invasive prenatal genetic testing has the characteristics of non-invasive sampling, no risk of abortion and high sensitivity. However, non-invasive prenatal genetic testing involves genetic testing, so the controversy over this technology has never stopped.
Non-invasive prenatal genetic testing costs
The best time for noninvasive prenatal genetic testing is the first and second trimester of pregnancy. Because of the high accuracy of non-invasive prenatal genetic testing, many prospective parents like it very much, and the cost of non-invasive prenatal genetic testing in different hospitals is different. However, because the method of non-invasive prenatal genetic testing is very detailed, the cost of non-invasive prenatal genetic testing is naturally not low.
Because it mainly analyzes the health status of the fetus by collecting the peripheral blood of pregnant women (5ml), extracting free DNA, and combining the new generation of high-throughput sequencing technology and biological information, the accuracy is very high, and the cost is slightly different according to the different detection cycle, so it is not easy to clearly price the cost of non-invasive prenatal genetic testing.
Accuracy of noninvasive prenatal genetic testing
Because non-invasive prenatal genetic testing is based on genes, the accuracy of non-invasive prenatal genetic testing in genetic testing is still very high. Therefore, the accuracy of non-invasive prenatal genetic testing is guaranteed, because it is based on genetic testing. It is reported that the accuracy of non-invasive prenatal genetic testing can be as high as 99%, and there is no need to be afraid of abortion when using non-invasive prenatal genetic testing methods.
Moreover, the best time for non-invasive prenatal genetic testing is in the first and second trimester, so the impact on infants is generally very small. It is only because of many uncertain factors of non-invasive prenatal genetic testing that it has been suspended for some time, but as far as the accuracy of non-invasive prenatal genetic testing is concerned, its authenticity is beyond doubt.