What harm does smoking and drinking do to health?

First, it will aggravate the degree of alcoholism. Recently, researchers at the University of Texas Health Science Center found that nicotine in cigarettes can significantly reduce the alcohol concentration in the blood, so smokers drink more alcohol on average than non-smokers. Researchers pointed out that alcoholics are pursuing a "toxic" effect. Because nicotine can lower the alcohol concentration in the blood, alcoholics who smoke can't get this feeling quickly, so they have to drink more alcohol. Nicotine can reduce alcohol concentration, but it cannot reduce acetaldehyde produced by alcohol decomposition in the same way, making acetaldehyde more toxic to brain, liver, heart and other organs. Second, it is easy to induce esophageal cancer. A foreign research group conducted the largest and most comprehensive analysis on the relationship between smoking and drinking to form cancer. Through the study of 2600 subjects with five kinds of cancers, it is confirmed that drinking a small amount of alcohol 1-3 times a day will not increase the risk of esophageal cancer, but the risk of esophageal cancer is 24 times that of non-drinkers, especially for heavy smokers, the risk of esophageal cancer will increase by 100 times. The reason is that cigarettes contain thousands of chemicals, including more than 50 carcinogens. These substances are covered by tar produced by burning cigarette butts and stored in the mouth, nose, throat and lungs. Smoking is considered to be one of the most important factors leading to lung cancer. Smoking while drinking will have a cumulative effect on carcinogenesis. When a smoker smokes a cigarette and drinks a mouthful of wine at the same time, tar substances in his mouth and throat will be washed down. Although alcohol itself is not a carcinogen, it is an organic solvent that can dissolve carcinogens and other harmful substances in cigarettes. When alcohol constantly stimulates the esophageal wall and causes mucosal congestion, carcinogens in tobacco will stimulate the esophagus more strongly when swallowed, which will easily lead to esophageal cancer over time. Third, the damage to cardiovascular system and liver is doubled. The "two-pronged approach" of tobacco and alcohol has a synergistic effect. The combination of the two hazards not only increases the risk of cancer, but also makes all kinds of "toxins" in tobacco and alcohol easily spread into the blood through the mucosal layer, causing many hazards to health, especially to the liver and cardiovascular system. Because the "chemical factory" of the liver will metabolize 95% of the absorbed alcohol into other chemicals, this will increase the burden of the liver and reduce its metabolic detoxification function, thus reducing the function of the liver to remove fat from the blood. Excess lipid substances will block capillaries, making it difficult for blood cells carrying nutrients and oxygen to reach all parts of the body. In addition, while drinking and smoking, carbon monoxide in smoke combines with hemoglobin in blood (the combining ability of carbon monoxide and hemoglobin is more than 200 times higher than that of oxygen and hemoglobin), which will seriously weaken the ability of red blood cells to transport oxygen and obviously lead to blood hypoxia. For example, patients with cardiovascular and cerebrovascular diseases, tobacco and alcohol "peers", are also easy to induce myocardial infarction, hypertension, and some will also cause serious consequences of brain cell death.