APOE gene guides the synthesis of apolipoprotein E, which is synthesized in liver and brain tissue, and also synthesized in other organs such as eyes, etc. APOE protein is closely related to lipid metabolism, and when the human body lacks it or its function is defective, it will lead to lipid metabolism disorders, which will in turn lead to the occurrence of a variety of cardiovascular and cerebrovascular When APOE is deficient or its function is defective, it can cause lipid metabolism disorders, which in turn can lead to the occurrence of various cardiovascular diseases, such as coronary heart disease, myocardial infarction and cerebral infarction, cerebral hemorrhage. In addition, APOE gene variants are also associated with the development of Alzheimer's disease and age-related macular degeneration.
There are 8 genotypes of APOE gene in the population, including ε1ε2, ε1ε4, ε2ε2, ε2ε3, ε2ε4, ε3ε3, ε3ε4, ε4ε4, and ε2ε3, and the result of the test shows that you are a carrier of ε2ε3 genotype. The frequency of this genotype in the Chinese population is about 12%.
From a genetic point of view, the ε2ε3 genotype affects your blood lipid levels, and you may be more likely to have lower levels of total cholesterol and LDL cholesterol. As a result you may be more likely than your peers to maintain normal lipid levels.
In addition, the test results show that your risk of coronary heart disease, cerebral infarction, and age-related macular degeneration is average, and your risk of myocardial infarction and Alzheimer's disease is low, which means that your risk of developing these five diseases in the future is comparable to, or lower than, that of the general public, and that you do not have a high predisposition to these diseases in terms of congenital heredity. In addition, the results show that you have a higher risk of cerebral hemorrhage, which means that you are more likely than the general population to develop cerebral hemorrhage under the same environmental conditions.
But the occurrence of these complex diseases is related to acquired environmental factors in addition to genetic factors. That's why it's important to prevent the disease on a daily basis.
Currently, the Chinese population is prone to cardiovascular and cerebrovascular diseases, so the above six diseases focus on cardiovascular and cerebrovascular diseases and reduce the risk factors, such as high-fat, high-cholesterol diet, high blood pressure, obesity, diabetes mellitus, atherosclerosis and so on.
Diet should be light, less oil, less salt, less sugar, try to stay away from fatty meat, fried food, cream products such as ice cream, pastries and cookies. The main food is a combination of coarse and fine grains, and the side food is mainly fish, lean meat, soybean and soybean products, all kinds of fresh vegetables and fruits. Vegetables, fruits can provide a wealth of vitamins and dietary fiber, is conducive to reducing the incidence of cardiovascular disease, especially dark green vegetables, yellow fruits and vegetables are rich in lutein content, can be nutritious to the retina, filtering harmful blue light, to prevent macular degeneration.
In addition, adhere to at least five days a week of moderate-intensity physical activity to maintain a normal weight, reduce the risk of cardiovascular disease. Aerobic exercise for a cumulative total of 30 minutes or more per day is the best choice. Young and middle-aged people can choose brisk walking, swimming, various ball games, dancing, etc., and the elderly can choose medium-speed walking, table tennis, badminton, swimming, square dancing, etc..
In addition to the above measures, regular testing of blood pressure, blood lipids and blood sugar indicators for early detection of cardiovascular and cerebrovascular abnormalities is also very important. For those who are already suffering from the three high diseases, you can choose the medical checkup program and increase the frequency of medical checkups, please follow the doctor's instructions. When eye discomfort or mental behavioral abnormalities, please consult a doctor in time.
The above is the interpretation of the APOE genetic test report, thank you for listening, goodbye!
The above is the report of the APOE genetic test, thank you for listening.