What are the influencing factors of sperm injection?

1. sperm factor: Nag)r et al. analyzed 966 ICSI treatment cycles and found that although there may be no normal sperm, no sperm at all or no motile sperm in semen, it is still possible to get pregnant. The key is whether viable sperm can be finally found and injected into the egg. Only one parameter of semen routine examination can affect ICSI results, that is, when the motility rate is 0, that is, there is no motile sperm, the existence of live sperm will be greatly affected, thus affecting ICSI fertilization.

2. Female factor: The woman's age does not affect the fertilization rate, but the pregnancy rate decreases with age. When the woman is over 40 years old, the live birth rate drops obviously. Usually, with the increase of age, the decrease of implantation rate is caused by the decrease of egg quality, which has little to do with endometrium.

3. Activation of eggs

4. Destroy the egg structure: Microinjection destroys the egg structure, which may eventually lead to egg death. In addition, the changes of injection process and culture environment, such as temperature, will also lead to irreversible changes of spindle.

5.PVP is a viscous solution. ICSI has many advantages when it is used to treat sperm: for example, if a little sperm precipitation is added to a drop of PVP, the flowing sperm can swim to the edge of PVP drop or the surface of PVP, while impurities and dead sperm can only stay in place or passively spread to a limited distance, thus separating live sperm.

6. Different types of oocyte puncture can predict the survival and fertilization ability of eggs.

7. egg shape.

Through the above introduction, I hope everyone can have a very detailed understanding of this. At the same time, it is also beneficial to increase everyone's understanding of this aspect.