Advantages and disadvantages of chorionic puncture technique
Benefits: check the health of the fetus.
Chorionic puncture is one of the traditional fetal examination items during pregnancy, and its clinical significance lies in confirming whether there are chromosomal abnormalities, neural tube defects and some hereditary metabolic diseases that can be reflected in amniotic fluid. The general operation time is 1 1~ 14 weeks, and there are two main methods. One is * * * sampling method. Under the guidance of ultrasound, a small tube is sent into placental villi through the * * and cervix, and a small amount of villi is sucked by an empty needle tube for inspection. The other is abdominal sampling method, which anesthetizes the abdominal skin locally. After the puncture needle enters the placental villi through the abdominal wall, a small amount of villi is also sucked by an empty needle tube for detection. Although this technology can play a key role in fetal health, it also has some defects.
Defects: high risk, incomplete test results.
Chorionic puncture may lead to bleeding, amniotic fluid overflow or persistent uterine contraction in women, which may lead to abortion. At the same time, although villous puncture can judge chromosome abnormality, the accuracy of examination is relatively limited. Even if the test results are normal, it does not mean that 100% healthy fetus is born. The diagnosis of genetic diseases can only be checked within the scope of conventional dominant diseases, and it is difficult to completely avoid the influence of genetic diseases on the fetus. If technicians are not skilled and inexperienced, it is very likely to destroy fetal tissues and cells, leading to fetal dysplasia or birth defects.
In addition, the deficiency of villus puncture is that once the fetus is abnormal, the expectant mother can only have an induced abortion operation, which is very harmful to the physical and mental health of the pregnant mother. If the abnormal problems of the fetus are not found in time and accurately, the baby will have fetal arrest, abortion, mental retardation, limb deformity and so on after birth.
In contrast, what is unique about the third generation IVF technology in the United States?
The PGS/PGD technology of the third generation test-tube baby in the United States has the same clinical significance as chorionic puncture, in order to ensure the health of the baby after birth and achieve the goal of prenatal and postnatal care. However, there are obvious differences between them in operation mode, detection range and accuracy.
PGS/PGD is a genetic screening and diagnosis technology before embryo transfer in the United States, which plays a vital role in reducing abortion rate, improving pregnancy quality and ensuring a good pregnancy in an all-round way. It is also the key reason why the success rate of IVF in the United States ranks among the top in the world.
As a pioneer in the application of PGS/PGD technology, the American Mengmei life expert introduced that PGS technology aims to screen the number and structure of 23 chromosomes in blastocysts before transplantation, and can accurately eliminate abnormal situations such as chromosome duplication, translocation, deletion and inversion. At present, this technology has developed to a new generation of NGS technology (gene sequencing), which can screen all chromosomes of blastocysts to the smallest deletion, with higher precision and accuracy. PGD technology is to judge whether blastocysts carry genes with gene defects and gene mutations leading to specific diseases by diagnosing gene mutation points, and effectively avoid the influence of 274 genetic diseases such as hemophilia, thalassemia, Down syndrome and meow syndrome on the fetus.
Under the guarantee of advanced technology, selecting healthy and high-quality blastocysts for transplantation can significantly improve the pregnancy rate and pregnancy rate.
As for whether PGS/PGD genetic testing technology will also have the risk of damaging fetal health, Mengmei life experts said that there is no need to worry about this. Because blastocysts are completely tested in the United States, blastocysts are mainly formed from fertilized eggs to the fifth day. Compared with the early embryos generally cultured in China, blastocysts are composed of more than 100 cells, which can be obviously differentiated into trophoblast cells (placenta will form later) and inner cell clusters (fetus will develop later), with very stable morphological structure, vigorous vitality and high adhesion ability. Using PGS/PGD technology to screen and diagnose the trophoblast cells of blastocyst will not damage the main cells of blastocyst at all, and its integrity can be well protected. In addition, Mengmei life experts have accumulated rich technical operation experience for more than 30 years, which can ensure the safety and success of genetic testing.
To sum up, the third generation IVF technology in the United States can avoid villus puncture. Because the accuracy and safety of the third-generation IVF technology in the United States is much higher than that of chorionic puncture, it really controls the health of the fetus before pregnancy and avoids the great harm caused by abortion to pregnant mothers. In addition, according to the excellent results of 50,000+test-tube cases of Mengmei Life, the babies born by the third generation test-tube PGS/PGD technology are as healthy and smart as the normal babies in all aspects. From the perspective of eugenics, American test-tube babies have more advantages.
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