Bigger hands and feet, thicker skin, joint pain ... Actually, I have acromegaly.

Inexplicably, the hands and feet are getting bigger, even the joints are painful and the skin is getting thicker. Don't ignore it. It may be acromegaly! /kloc-Akun (pseudonym), a 0/35-year-old automotive sheet metal worker, was recently diagnosed as acromegaly, with a rough face, enlarged palms, thicker fingers and enlarged feet. In addition, the patient developed symptoms of hand numbness. The doctor accidentally found that the patient had 1 brain tumor, which was very close to the optic nerve. Fortunately, the operation avoided the risk of blindness.

Lin Wenyu (left), vice president of Dali Renai Hospital, and Yang Mengyin, director of neurosurgery. (Photo courtesy of Dali Renai Hospital) The patient's face is rough and his palm is getting bigger ... The doctor highly suspects acromegaly.

Lin Wenyu, vice president of Dali Renai Hospital, said that the patient came to the hospital because of hyperglycemia complicated with ketoacidosis, and the glycosylated hemoglobin was found to be 18.6% (normal value

In addition, it was found that the palm of Akun's hand was almost 1.5 times larger than that of ordinary people, and the thickness of his fingers was twice that of ordinary people. "It is highly suspected that it is acromegaly." Later, after the growth hormone test, the blood test result was 30 ng/mL (Nike /mL) (normal random value

Kun (pseudonym) has recently been diagnosed as acromegaly by doctors with rough face, enlarged palms, thick fingers and enlarged feet. (Photo courtesy of Dali Renai Hospital) The patient's brain tumor is close to the optic nerve, and surgical resection is far from the risk of blindness.

Lin Wenyu, vice president, arranged a brain magnetic resonance (MRI) examination and found a very large tumor (2. 17x2.65) in the sellar region of the skull base. Because the pituitary gland has the largest volume of 1cm3, the tumor is nearly 3cm in diameter, located directly behind the eyes, in the center of the brain and close to the optic nerve. If it is serious, it will be blind. The cause is caused by genetic variation, but fortunately it is benign, non-metastatic and non-invasive. After consultation, Yang Mengyin, director of neurosurgery department, used minimally invasive surgery to directly enter the skull base from nostril and make a hole, which was successfully taken out about 1 hour.

Lin Wenyu, vice president, said that acromegaly is hard to prevent, because after the human growth plate is closed, growth hormone is still secreted excessively. The initial symptoms are bigger hands and feet, bigger shoe size, and more prominent forehead, chin and nose. Other symptoms include: joint pain, skin thickening, deep voice, headache and poor eyesight. If it happens before the growth plate heals, it may grow to more than 200 cm, which is called "gigantism"; If it happens in adulthood, because the growth plate has healed, the height will not increase significantly, the ends of limbs will become thicker and thicker, and the liver, kidney and pancreas will also swell.

After the operation, Akun regained a healthy life, from the preoperative average pre-prandial blood glucose of 250 ~ 300mg/dl to 120 mg/dl, the growth hormone decreased to normal, the IGF- 1 (insulin-like growth factor) also decreased, the swelling of organs stopped, and the symptoms of carpal tunnel syndrome were improved.