? Speaking of which, some friends will have questions. What is acid-base imbalance in human body? Aren't people neutral individuals? What does this have to do with getting sick?
First, the importance of acid-base balance to human body
? Why do we have this idea? Because everyone has always been sick, they naturally go to the hospital to see a doctor, a psychologist for headaches, a dentist for toothaches and a doctor for colds. All these diseases have injections, and taking medicine may be nothing, and no one goes to find out why they are sick until people get high blood pressure, stroke and diabetes, which can't be solved by taking medicine alone, even taking medicine for life, and cancer that is already life-threatening. When patients searched everywhere for a life-saving prescription, but it was always fruitless, everyone realized that treatment should not only treat headaches, but also find the root cause. Where is the root?
? Professor Lei Weng, winner of the international Nobel Prize in Medicine, pointed out: "Acidic constitution is the source of all diseases", and a Japanese doctor of medicine, Hideo Ogara, pointed out: "More than 80% of human diseases are caused by acidic constitution."
? What kind of constitution is that man? What is the specific situation?
? In chemistry, acidity refers to the concentration of hydrogen ions in solution, which is expressed by PH value. We are familiar with this, but the pH value is of great significance to life. For example, the cultivation of microorganisms in microbiology needs to be carried out in a certain culture solution; The activity of enzyme can only be shown in a certain PH range; Every part of the human body requires its body fluid to have a certain PH value, otherwise it will affect tissue activities. The PH values of body fluid, blood, bone marrow, saliva, gastric juice, duodenum and feces recorded by western medicine diagnostics are 7.0-7.4, 7.35-7.45, 7.3-7.5, 6.5-7.5, 1.0-3.5, 4.2-8.2 and 4 respectively. All of us are made up of water, because 70% of our body weight is water, also called body fluids. The PH value of our healthy body fluids is usually kept between 7.35 and 7.45, which is weakly alkaline.
? Why is the pH value of normal body fluids weakly alkaline rather than acidic? From the perspective of biological evolution, it can be explained that all living things on the earth evolved from the ocean, and people are no exception. Seawater is weakly alkaline with a PH of 7.4. Human beings originated from a weakly alkaline environment, so human body fluids are also weakly alkaline, with a PH of 7.4. Our embryo in the womb looks like a fish, and then gradually becomes human. In this process, the fetus has been living in the amniotic fluid in the uterus, which is weakly alkaline, so we are born in the uterus, and the pH value of normal body fluids is weakly alkaline.
? From the medical and biochemical point of view, the acidity and alkalinity of human body is determined by an acid-base balance buffer system in the body. The acid-base balance buffer system of human body consists of carbonate buffer pair H2CO3-NaHCO3 (main buffer pair), phosphate buffer pair NaH2PO3-NaHPO4, hemoglobin buffer pair (hemoglobin-hemoglobin salt) and plasma protein buffer pair (plasma protein-plasma protein salt). Maintaining the acid-base balance of the human body mainly depends on the buffering system of the human body, the respiration of the lungs, the excretion and reabsorption of the kidneys.
? In the normal metabolism process, the human body constantly produces acidic substances and alkaline substances, and also ingests acidic substances and alkaline substances from the daily diet. Acidic substances and alkaline substances are constantly changing in the human body, and this change must rely on the body's regulatory function to maintain a relative balance. This balance is acid-base balance, and the range of balance is PH 7.35-7.45. This PH value is most suitable for cell metabolism and systemic survival. All physiological function changes and biochemical reactions of human body are carried out under the condition of stable PH value, such as cell protein synthesis, energy exchange, information processing, enzyme activity, etc., which all require a stable pH environment. The results of laboratory experiments show that if the PH value of human blood is higher than 7.45 or lower than 7.35, human diseases will occur. The variation range of blood PH value is very small, and the difference of 0.0 1 may be close to death. The PH value of body fluids remaining in the body varies widely, such as duodenal juice, gastric juice, urine and feces. When the PH value of human body fluid is lower than neutral 7, it will cause serious diseases, and when it drops to 6.9, it will become a vegetative state. If it is only 6.8-6.7, people will die. Of course, too high PH can also lead to alkalosis, so the human body needs acid-base balance to maintain the health of life.
Second, how is the acidic constitution formed?
? Those friends are thinking, since the human body is alkaline from the beginning, how can it become acidic?
? According to modern popular saying, we call hyperlipidemia, hypertension, diabetes, obesity, cardiovascular and cerebrovascular diseases and even cancer "rich diseases". Why is it called "the disease of wealth" mainly because of the economic development, the improvement of people's living standards, everything on the table and the great changes in diet structure? Where is the wealth? Just one word "eat". As the saying goes, food is the most important thing for people, and diet is the lifeblood of people. But we eat too well and eat too much in our daily life, which leads to "diseases from the mouth". Some people call these diseases "diseases of modern civilization". Professor Zhao Lin, the chief health education expert of the Ministry of Health, pointed out at the seminar on "Human Health and Acid-base Balance": "We modern people swallowed it unconsciously.
? Some people will say that I didn't eat anything special, just fish, meat, poultry, eggs, oil, rice, noodles and fruits and vegetables. Yes, it is these things you eat that have an impact on your health. We know that air and water are the basis of human existence. Protein, fat, carbohydrates (also known as sugar), vitamins, minerals and cellulose are the six nutrients that our human body needs. Among these six nutrients, protein, fat and carbohydrate provide energy and calories for human body, which mainly come from fish, meat, poultry, eggs, oil, rice and noodles. Vitamins and minerals regulate human physiological functions, mainly from vegetables and fruits. Cellulose is the only nutrient without nutrition, but it is a necessary substance for digestion and absorption. We call protein, fat and carbohydrate as high-nutrient substances, also called acidic substances (that is to say, fish, meat, poultry, eggs, oil, rice and noodles, on the one hand, provide us with nutrition, on the other hand, they produce acidic substances after metabolism in our bodies):
Sulfur-containing and phosphorus-containing amino acids produced by protein decomposition (generated nucleic acids are decomposed into uric acid).
Fatty acids produced by lipolysis, acetoacetic acid (also known as ketone body), b- hydroxybutyric acid.
Lactic acid, pyruvic acid and glyceric acid produced by sugar decomposition.
? As mentioned earlier, the human body has a buffer system to adjust the acid-base balance, which is the alkali reserve in plasma and organs such as liver, kidney and lung. By adjusting the acid-base balance system of human body, the acid-base balance of human body under scientific and reasonable diet conditions can be ensured. However, if people eat improperly and eat too much acidic food, which exceeds the ability of the human body to regulate the acid-base balance, then the acid-base balance of the human body will be destroyed, making the acid-base balance in the body unbalanced, and even mild acidosis, which is what we call acidic physique; On the other hand, some people eat a lot of acidic substances, and may not have an acidic constitution for the time being, but this does not mean that everything is normal. Just because they have more alkali reserves in their bodies, they have adjusted the acid-base balance in time. But acidic substances are still in the body after all, only temporarily neutralized by the alkali in the body, but the pollution caused by body fluids cannot be eliminated. If it is accumulated for a long time, the internal environment of the human body will deteriorate seriously, and it will also form an acidic constitution.
? Some people may say that I am old now, and my gastrointestinal function is not very good. I usually eat lightly and basically don't eat big fish and meat. Can it still cause acidic constitution? First of all, acidic constitution is caused by unreasonable long-term diet structure. In addition, there is another link that everyone easily ignores, that is, the intake of oil. At present, the World Health Organization stipulates that the intake of oil is half an ounce (25 grams) per person per day, and a family of two should eat one or two ounces per day and three kilograms per month. People with diabetes have less oil, only10g a day. Why limit the amount of oil? Because oil is fat and fat is acidic. I used to eat animal oil when the conditions were bad. Why do people eat less now? Because animal oil is saturated fat, long-term consumption will increase blood lipid and easily cause arteriosclerosis. In the 1980s, our living conditions were not very good, but why many people got blood clots was actually related to eating animal fat. Now that the conditions are good, we begin to pay attention to the influence of edible oil on human health. For example, we eat vegetable oil such as sunflower oil and tea oil every day, or eat reasonable blended oil, most of which contains unsaturated fat. Why does it affect our health? Because vegetable oil will become saturated fat after being heated at high temperature, too much oil intake and unreasonable cooking methods are also one of the most important factors that cause acidic constitution in our daily diet.
? We are all concerned about the protection of the external environment now. In fact, our human body also has an internal environmental protection problem, which refers to the pH value of our human body. Let's use an example to illustrate that you may understand it better: fish farming in fish tanks. We know that if the water in the aquarium is clean, the fish will have a very high quality of life. If the water is polluted, the fish will get sick and die. If we keep goldfish at home, we have to change the water in two or three days, otherwise the goldfish will die. Why? Because the water in the fish tank has been polluted by the waste discharged by the fish. Similarly, our human body is like a goldfish bowl, and human body fluids are like water in a fish bowl (70% of human body weight is water, also called body fluids). All tissues and organs of human body and nearly 6 trillion cells live in 70% water. When the water in the goldfish bowl is polluted or deteriorated, the fish will get sick and die. After the body fluid is polluted by acidic substances, cells will deteriorate or even die, and tissues and organs will mutate, leading to pathological changes in organ function and various diseases.
? Compared with the 1960 s, the diet structure of our present era has undergone earth-shaking changes. There are four main factors to form acidic constitution: overnutrition, less exercise, excessive pressure and environmental pollution. Among them, we overeat, eat too much and eat too well, and the accumulation of acidic substances in the body is the key factor to form acidic constitution.
Third, the harmfulness of acidic constitution
? Human cells are born to run in alkaline environment, but they also produce and secrete acids. Cells produce acids during operation, but these are weak acids and organic acids. Unlike the acid produced by acidic food, it is decomposed into carbon dioxide and water and discharged from the lungs. But the acid produced by acidic food is strong acid (phosphoric acid, phosphoric acid), which will threaten human health. These large amounts of acidic substances must be neutralized by the buffer system in the body before being excreted by the kidneys. In the whole neutralization and discharge process, a lot of minerals will be consumed. If these acids are not neutralized, they will burn sensitive tissues when passing through the digestive tract or excretory system. For example, when you urinate, you will feel pain or burning sensation. The main substance used by the body to neutralize acid is mineral sodium (preferably sodium in vegetables and fruits, not salt). When you eat a lot of acidic food, your body will use a lot of sodium ions to neutralize it. When sodium ion is seriously insufficient, your body will mobilize minerals such as calcium in bones and potassium in cells to participate in hard work, which gives a good opportunity for disease development.
? The first is diabetes.
? What is the relationship between this hyperglycemia and acidic constitution? Diabetes mellitus is a disorder of lipid and sugar metabolism and a typical acidic constitution. 95% of diabetes is type II diabetes. In fact, type II diabetes is not necessarily due to insulin deficiency, but to insufficient insulin activity or decreased sensitivity. For example, there are ten sugar molecules in blood, and our islet cells secrete ten insulin to bind to the sugar molecules, but only five of them really work (just like ten of us go to work, only five are really dry, and the rest are sleeping), resulting in more and more sugar molecules without insulin binding, and blood sugar is of course high. According to the research of the World Health Organization, the activity of insulin will decrease by 30% every time the pH value of human body fluids decreases by 0. 1, thus aggravating the condition of diabetes. However, the disorder of lipid and sugar metabolism in diabetes leads to the continuous production of acidic substances. First, glucose is oxidized by oxygen to carbon dioxide, water and 38 ATP needed by human body. However, in acidic environment, the oxygen carrying capacity of red blood cells decreases by 30% every time the PH value decreases by 0. 1, so acidic constitution is generally anoxic. At this time, one glucose will be anaerobically fermented into two lactic acids and two ATP. Not only will there be less energy, but people will always feel tired, and insufficient energy will consume body fat. At this time, ketone bodies will also be produced, and ketone bodies are also acidic. Lactic acid and ketone bodies will make the blood more sour, and also reduce insulin activity, resulting in a vicious circle. We know that diabetes is not terrible, but a complication, because hyperglycemia is suitable for the reproduction of bacteria and viruses. Diabetes is bound to have complications. If the blood sugar is well controlled, the complications will be lighter and come later. If the blood sugar is not well controlled, the complications will come earlier and heavier. CCTV's Road to Health has a program called Acidity and Diabetes Complications. Experts suggest that to prevent diabetes, we should first prevent acidity and prevent complications of diabetes, and first improve your acidity.
? Second, cancer.
? Cancer is also a typical acidic constitution and is called the third killer. Cancer is caused by cell mutation caused by pathogenic factors. At present, there are more than100000 cancer patients in the world, and there are about1600000 new cancer patients in China every year. Cancer is closely related to acidic constitution. 100% of cancer patients' body fluids are acidic, and the more advanced, the stronger the acidity. Acidic constitution is a hotbed of malignant tumors. The living conditions of cancer cells and normal cells are just the opposite. Normal cells in the human body need neutral and weakly alkaline body fluids and an adequate living environment with oxygen. In acidic body fluids, the activity of red blood cells is also low, and the ability to transport oxygen is reduced. The PH value of blood drops by 0. 1 unit, and the amount of oxygen delivered drops by 30%. The human body produces about 10000 cancer cells every day. However, because the human immune function is normal, cancer cells can be swallowed up in time, so ordinary people are not easy to get cancer. When the PH value of human body fluid is 6.85-6.95, the activity of immune cells decreases, but the activity of cancer cells is greatly enhanced, and the ability of immune cells to recognize and resist cancer cells decreases. At this time, the number of cancer cells has greatly increased. When the number of cancer cells in the body reaches 1 100 million, the tumor is one centimeter in size. At that time, people will feel uncomfortable, eat less, anemia and fatigue. In addition, the toxin L50 produced by cancer cells is also acidic, which will destroy the human immune system and cause severe pain. The metastasis of cancer cells has an important premise, that is, cancer cells must first combine with blood vessel walls, and then molecules, and this combination can only be carried out under acidic conditions. The crazy growth of cancer cells will rob and absorb a lot of nutrients, which will lead to the lack of nutrients in good cells and make the human body thinner.
? Three, cardiovascular and cerebrovascular diseases (hypertension, hyperlipidemia, high blood viscosity)
? When human blood is in an acidic environment, the ability of red blood cells to transport oxygen, nutrients and metabolites (especially CO2) will decrease. On the one hand, the oxygen and nutrients needed by various parts of the human body can not be supplied, on the other hand, the metabolites that should be excreted can not be excreted in time and remain in the blood. These two factors will lead to the variation or death of vascular endothelial cells and smooth muscle cells due to ischemia and hypoxia;
? The normal defense function of white blood cells is reduced, so that harmful substances such as viruses, bacteria and endotoxin in human organs and tissues cannot be removed, and immune complexes will also be deposited or retained in various organs and tissue fluids. On the other hand, the phagocytic function will also be reduced, resulting in the inability to swallow harmful substances and endotoxin in the blood, thus destroying the normal metabolism of various cells in the blood vessel wall;
? Acidic environment will stimulate the hypercoagulability mechanism of platelets, which is characterized by excessive adhesion, excessive accumulation and excessive release. Endless platelet aggregation and endless stimulus release lead to thrombosis, vascular occlusion, infarction and so on.
? Acidification of blood metabolic environment leads to the decrease of protein production in plasma, which in turn leads to the decrease of plasma colloid osmotic pressure. Therefore, the water in the tissue fluid can not be attracted to the blood vessels, resulting in a significant reduction in the water in the blood. Blood viscosity increases, causing atherosclerosis.
Green algae (Chlorella pyrenoidosa) can transform acidic constitution into healthy weak alkaline constitution. For more information about green algae (Chlorella pyrenoidosa), please refer to Green Xianyou Green Algae/Chlorella.