Sismin's instructions
Drug name
Common name: loratadine tablets.
Product name: loratadine tablets (Xi Simin)
English name: loratadine tablets.
Main ingredients Each tablet of this product contains 10 mg loratadine. The auxiliary materials are sodium dodecyl sulfate, starch, microcrystalline cellulose, povidone K30, sodium carboxymethyl starch, talcum powder and magnesium stearate.
Powdering
Chemical name: 4-(8- chloro-5,6-dihydro-1 1H- benzocycloheptane [1, 2-b] pyridine-1 1- alkenyl)-/kloc.
Molecular formula: C22H23ClN2O2
Molecular weight: 382
This product is a white or white-like tablet.
Indications/Functions: Mainly used to relieve symptoms related to allergic rhinitis, such as sneezing, runny nose, itchy nose, stuffy nose, itchy eyes and burning sensation. Symptoms and signs of nose and eyes can be quickly relieved after oral administration of drugs. It is also suitable for relieving the symptoms and signs of chronic urticaria, pruritic dermatosis and other allergic dermatoses.
Specification and model 10mg*6s (Sismin)
Administration and dosage by oral administration. 1./kloc-adults and children over 0/2 years old: 1 time daily, each time1tablet (10 mg). 2.2 ~ 12 years old children: weight >; 30 kg: one day 1 time, once 1 tablet (10 mg). Weight ≤30 kg: 1 time, one and a half tablets a day (10 mg).
The adverse reaction was 1. At the recommended dose of 10mg per day, this product has no obvious sedative effect. 2. Common adverse reactions include fatigue, headache, drowsiness, dry mouth and gastrointestinal discomfort, including nausea, gastritis and rash. Rare adverse reactions include alopecia, allergic reaction, abnormal liver function, tachycardia and palpitation. (Please refer to the instruction manual for details).
Contraindications: it is forbidden for those who are allergic to the ingredients of this product.
Precautions 1. Please use it under the guidance of a doctor for patients with severe liver function deficiency. 2. Pregnant women and lactating women should use it with caution. 3. Stop using this product about 48 hours before skin test, because antihistamines can prevent or reduce the positive reaction of skin test. 4. It is forbidden for those who are allergic to this product, and should be used with caution for those who are allergic. 5. It is forbidden to use this product when its characteristics change. 6. Please keep this product out of the reach of children. 7. Children must use it under the supervision of adults. 8. If you are using other drugs, please consult a doctor or pharmacist before using this product. The safety and effectiveness of this product for children under 9.6 years old have not been determined. Please consult a doctor or pharmacist. 10. Patients with hepatic and renal insufficiency should reduce the dose. It is recommended to take 10 mg every two days under the guidance of a doctor, for a total of 1 time. 1 1. Because the plasma concentration of elderly patients is higher than that of healthy people, elderly patients should pay close attention to the occurrence of adverse reactions when using this product for a long time. 12. Excessive use of this product (40- 180 mg) in adults may cause drowsiness, arrhythmia and headache. Once the above symptoms appear, symptomatic support treatment should be given immediately. Treatment measures include inducing vomiting, and then using activated carbon to absorb the absorbed drugs. If vomiting is unsuccessful, gastric lavage, catharsis and dilution of intestinal drug concentration with normal saline are needed. Hemodialysis can not remove loratadine, and peritoneal dialysis can remove this product has not yet been determined.
Children use drugs according to the doctor's advice.
Elderly patients use drugs according to doctor's advice.
Pregnant women and lactating women use drugs according to the doctor's advice.
Drug interaction 1. Taking ketoconazole, macrolide antibiotics and cimetidine at the same time will increase the blood concentration of loratadine, so it should be used with caution. Before the interaction with loratadine is clear, other drugs known to inhibit liver metabolism should be used with caution. 2. If it is used together with other drugs, drug interaction may occur. Please consult a doctor or pharmacist for details.
The drug overdose is not clear.
Pharmacology and Toxicology This product is an effective and persistent tricyclic antihistamine, and it is a selective peripheral H 1 receptor antagonist. It can relieve various symptoms caused by allergic reaction.
Pharmacokinetics is unclear.
Storage and shading, sealed preservation.
Aluminum-plastic packaging, 6 pieces/plate/box.
The validity period is 48 months.
Implement the standard YBH 16022004.
Approval number: National Medicine Zhunzi H20070030
Xi anrangsang pharmaceutical co., ltd.
What about Xi Simin?
Loratadine is a white crystalline powder, odorless and tasteless, soluble in methanol, ethanol and acetone, and soluble in ether. It is the zwitterionic characteristics in the molecular structure of the second generation antihistamines that make them have no obvious central inhibitory effect. It is mainly used for preventing and treating allergic rhinitis, chronic idiopathic urticaria, allergic asthma and atopic dermatitis, seasonal or perennial allergic rhinitis, urticaria and skin itching caused by allergens.
Taking loratadine tablets together with ketoconazole, macrolide antibiotics, cimetidine, theophylline and other drugs will increase the blood concentration of loratadine, so it should be used with caution. Before the interaction with loratadine is clear, other drugs known to inhibit liver metabolism should be used with caution. If used together with other drugs, drug interactions may occur. Please consult a doctor or pharmacist for details.
Loratadine tablets is an effective and long-lasting tricyclic antihistamine and a selective peripheral H 1 receptor antagonist, which can relieve various symptoms caused by allergic reactions. Therefore, loratadine tablets has a good therapeutic effect on allergic reaction symptoms.
What about skin allergy?
Do not use alkaline washing for skin allergy.
Using alkaline soap, washing powder or detergent can easily lead to dry skin and aggravate chapped and itchy skin. Allergy can be relieved by topical allergy repair cream. Bathing with soap can inhibit sebum secretion and make skin drier, thus aggravating itching. Therefore, such patients can try soap rich in oil.
Don't abuse drugs to treat skin allergies.
Drug abuse leads to the aggravation of skin-skin diseases everywhere, such as facial seborrheic dermatitis, intractable hormone-dependent dermatitis, acute erosive exudative eczema and so on.
How to judge whether you are allergic to mites?
1, the skin gradually becomes rough, dull, yellow, greasy and peeling.
2, get up in the morning with soft paper, gently wipe the sides of the nose or forehead where there is oil seepage.
3, the pores gradually become thicker and bigger, and the pores around the nose have blackheads and are increasing.
4, face acne, acne, acne, papules repeated attacks, sensitive skin.
5. Red pimples and itching appeared on the chest and back.
6, chicken skin, folliculitis, hair follicle keratinization, dermatitis and other skin diseases.
7, peeling, broken hair, split, dandruff increased phenomenon.
8. There is itching on the face at night, and various discomfort symptoms such as itching appear all over the body before and after going to bed.
If your symptoms are very consistent with the above two points, then you are most likely allergic to mites. However, in order to ensure the accuracy of judgment, we still have to go to the hospital for allergen testing, and its results are the most accurate.
When confirming mite allergy, first of all, we should do a good job of sanitation and cleaning, such as washing and drying quilts frequently, dust removal, etc., so as to effectively prevent mites.