The maintenance of respiration mainly depends on the stimulation of peripheral chemoreceptors by hypoxia, which excites the respiratory center reflexively and maintains normal respiratory movement.
Inhalation of high-flow oxygen can increase the partial pressure of blood oxygen, reduce the stimulation to peripheral chemoreceptors, make breathing shallow and slow, reduce carbon dioxide discharge, aggravate carbon dioxide retention, and lead to respiratory acidosis and pulmonary encephalopathy. Therefore, it is necessary to continue low-flow oxygen inhalation and slowly correct hypoxia.