Peptides are bioactive substances that participate in various cell functions in organisms. There are hundreds of peptides in organisms, which are essential participants for the body to complete various complex physiological activities. All cells can synthesize peptides. It involves various fields of human body, and its importance lies in regulating the physiological functions of various systems and cells in the body and activating related enzyme systems in the body. It is an important physiological regulator, which is very important for human cell activity, functional activity and life existence.
2 1 century will be the century of peptides.
In the past, science thought that protein was absorbed by human body in the form of amino acids. In recent years, it is scientifically believed that protein is absorbed by human body mainly in the form of peptide. This is a major discovery of human absorption mechanism and a major breakthrough of protein's absorption theory.
It's been a whole century since the first polypeptide was artificially synthesized by DUCTIVS. With the rapid development of molecular biology and biochemical technology, amazing and epoch-making progress has been made in the study of peptides. It has been found that there are tens of thousands of polypeptides in organisms, and all cells can synthetic peptides. At the same time, almost all cells are also regulated by polypeptides, involving hormones, nerves, cell growth and reproduction. Polypeptides have strong activity and diversity, and are the focus of research and development in the fields of biology, medicine and pharmacy in the world. Bioactive peptides will attract worldwide attention, and 2 1 century will be the century of peptides.
First, the history of polypeptide research
All living things, from the simplest virus to human beings, have the same 20 amino acids in their complex protein structure, which constitutes the protein world. During the in-depth study of protein in biology, a class of intermediate substances composed of amino acids but different from protein was found. This substance with protein properties is called polypeptide. Peptide is a simpler and smaller molecular weight compound than protein, which is composed of amino acids linked by peptide bonds. Polypeptide has the dual functions of regulating physiological functions and providing nutrition for the body, which affects almost all metabolic synthesis of the human body. Peptides containing less than 10 amino acids are called oligopeptides, and the rest are called polypeptides; A polypeptide with more than 50 amino acids is called protein.
1902, Bayliss and Starling, two physiologists at the University of London School of Medicine, discovered a magical substance that can stimulate the secretion of pancreatic juice in the gastrointestinal tract of animals. They call it secretin. This is the first time that human beings have discovered peptides. Because this discovery initiated the functional study of peptides in endocrinology and had far-reaching influence, the Nobel Committee awarded them the Nobel Prize in Physiology.
193 1 year found a polypeptide called substance p, which can excite smooth muscle, relax blood vessels and lower blood pressure. Scientists began to pay attention to the effect of peptides on the nervous system, called neuropeptides.
1953, the biochemical team led by Vigneand completed the synthesis of the bioactive peptide oxytocin for the first time. Since then, the polypeptide research in the 1950s mainly focused on various polypeptide hormones secreted by pituitary gland.
1952, biochemist Stanley cohen implanted sarcoma into mouse embryos, and found that the growth of sympathetic nerve fibers in mice was accelerated and the ganglion was obviously enlarged. Eight years later, 1960, it was found that it was a polypeptide at work, and it was called nerve growth factor (NGF).
In the late 1950s, Merifield invented the solid-state synthesis of peptides and won the Nobel Prize in chemistry.
In the early 1960s, amazing progress was made in the study of peptides, and the structural analysis and biological functions of peptides were successively achieved.
1965, scientists in China completed the synthesis of bovine crystalline insulin, which is the first synthetic peptide-like bioactive substance in the world.
In 1970s, the research on neuropeptides reached its climax, and enkephalins and opioid peptides were discovered one after another, which entered the research on the effect of polypeptides on the development of biological embryos. 1975, Hughes and Kosterlitz isolated endogenous peptides from human and animal nerve tissues, which enriched the content of biopharmaceuticals and opened up a new field of biopharmaceuticals. At this time, as many as 100 cell growth regulators were found, which exceeded the sum of polypeptide hormones and other active peptides used in clinic.
1986 the nobel prize in physiology was awarded to StanleyCohen, who discovered polypeptide growth factor (NGF), in recognition of his pioneering a new field of broad importance to basic scientific research. Since 1980s, polypeptide research has gradually developed into an independent specialty, covering the latest disciplines in life science, such as molecular biology, biosynthesis, immunochemistry, neurophysiology, clinical medicine and so on. Especially with the introduction of genetic engineering, many peptides can be expressed on a large scale. 1987 the United States approved the first gene drug-human insulin.
In 1990s, the Human Genome Project was launched. With the decoding of genes by scientists, the research and application of peptides are unprecedentedly prosperous. It is found that all life phenomena of gene expression are presented by protein, and genes are information instructions for synthesizing protein, but all physiological activities of human body need to be completed by protein in the end. So scientists turned their attention to another huge project of bioengineering, namely protein Group Project. Protein Project is based on protein's knowledge of structure-function relationship, and through careful molecular design, protein is transformed into a new mutant protein that meets human needs. People can redesign the gene encoding a certain protein according to their needs, so that the synthesized protein structure can meet people's requirements. Because the protein Project was developed on the basis of genetic engineering, it has many similarities with genetic engineering technology in technology, so the protein Project is also called the second generation genetic engineering. Peptide is a structural fragment of protein and an active gene part of protein. In fact, most of the functional proteins in animals are carriers, and their functions are accomplished by peptide fragments hanging on them. Peptides can not only deeply study the properties of protein, but also provide basic materials for the transformation and synthesis of new protein. Therefore, the protein Project is a study of peptides in a sense.
Polypeptide is a bioactive substance involved in many cell functions in organisms. With the rapid development of molecular biology and biochemical technology, since biochemists have used synthetic peptides artificially for more than 40 years, the research of peptides has made amazing and epoch-making progress. It has been found that there are tens of thousands of polypeptides in organisms, and all cells can synthetic peptides. At the same time, almost all cells are also regulated by polypeptides, involving hormones, nerves, cell growth and reproduction. Cell differentiation, neurohormone transmitter regulation, tumor lesions and immune regulation in life activities are closely related to active peptides. With the progress of modern biotechnology and the development of life science, more and more attention has been paid to the physiological functions of peptides in organisms, especially the elucidation of the physiological functions and structures of many active peptides, which has promoted the scientific research of active peptides.
Second, the prospect of polypeptide application
Polypeptide is a compound whose molecular structure is between amino acid and protein, and any protein has a peptide bond structure. The molecular structure of most protein is very complex, with a relative molecular weight of over 654.38+ million. The molecules are highly compressed and folded, forming a three-dimensional regular entity. It is these complex structures that seriously affect the digestion and absorption rate of the body. Human peptides come from protein's nutrition, mainly in two aspects. One is that protein produces peptides in the process of food digestion, which are absorbed by the body, and the other is that the cells in the body directly synthesize amino acids, which is the degradation product of protein. Polypeptide and protein have the same structure and are composed of amino acids. From the point of amino acid nutrition, they are the same. However, the molecular weight of polypeptide is much smaller than that of protein, and it has some physiological regulation functions that protein does not have.
Peptide is superior to high protein (macromolecular protein), and their functions are quite different. First of all, peptide is the messenger of information, which causes various positive or negative physiological activities and biochemical reaction regulation with different practical functions; Secondly, the activity is high, and the polypeptide can play its unique physiological role in trace and low concentration; Third, the molecular weight is small and it is easy to be modified. Compared with protein, it is easier to synthesize. However, high protein (macromolecular protein) does not have this characteristic. Fourthly, the properties of protein can be deeply studied through the polypeptide fragments, providing basic materials for the transformation and synthesis of new protein. If amino acid is the second deep development, then peptide is the product of the third deep development and high protein.
Peptides are superior to amino acids. First of all, they are absorbed faster than amino acids. Second, it is absorbed by the body in a complete form; The third is active absorption (amino acids are passive absorption); Fourth, consumption is low. Compared with amino acids, peptide absorption has the characteristics of low or no energy consumption. After being absorbed through the duodenum, peptides directly enter the blood circulation, delivering their own energy and nutrition to all parts of the human body. Fifth, peptides absorb many amino acids and are unsaturated; Sixth, there are only 20 kinds of amino acids, and their functions can be counted, while peptides can be synthesized into thousands of kinds with amino acids as substrates. Seventh, there is no competition and inhibition in the operation of various peptides.
As a basic nutrient, peptide is more easily absorbed than amino acids and has high bioavailability. Some peptides with small molecular weight also have the functions of preventing and treating diseases and regulating human physiological functions, which protein and his amino acids do not have. Hydrolysates of protein not only meet the needs of human growth and development as nutritional products, but also have special physiological regulation functions, which cannot be explained by the amino acid composition of the original food. Functional peptides are made by cutting macromolecular protein by biotechnology. The cut small molecule protein fragment can produce physiological regulation function that the original protein does not have. For example, insulin, the most successful application of polypeptide in modern medicine, almost saved the lives of diabetic patients all over the world; Growth hormone (hGH) is the most popular functional health care product in Europe and America, and it is a polypeptide that can promote growth and resist aging. Soybean peptides prepared from soybean protein have the functions of reducing blood fat, losing weight and improving exercise ability. Albumin polypeptide made from egg white has the functions of improving immunity and promoting digestion. Aspartame, the most widely used polypeptide in food industry, is a low-calorie edible flavoring agent; It mainly comes from corn. CPP casein phosphopeptide (also known as-calcium absorption promoting peptide) is the most added peptide for children, women and the elderly, which has the functions of promoting calcium absorption and anti-osteoporosis. It comes from dairy products. Collagen polypeptide and EGF, the two most fashionable polypeptides in cosmetics, are the first choice for skin anti-wrinkle and moisturizing, and EGF is the regeneration factor of skin. Is an excellent representative of peptide products; The most remarkable sign of the development and progress of cosmetics industry characterized by traditional fine chemicals to modern biotechnology is the application of polypeptide technology.
Because polypeptide itself is a small molecular substance, the nutritional characteristics of undigested and directly absorbed polypeptide can improve the curative effect and reduce the digestive burden of gastrointestinal tract, which has obvious advantages for people with poor digestive function. Studies have proved that peptides with a relative molecular weight below 3400 will not cause allergic reactions. Bioactive peptides obtained from natural food proteins by modern biotechnology are called functional peptides. Scientific experiments have proved that functional peptides can not only provide nutrients needed for human growth and development, but also have special physiological functions; It can reduce blood fat, delay aging, beautify the body, resist oxidation, depression, fatigue, improve sleep, enhance memory and inhibit tumors. Can promote the absorption of protein, vitamins and various beneficial trace elements.
The development and application of bioactive peptides is a hot spot in the field of bioengineering, which is widely used in medicine, health care, food, cosmetics and other industries, and is forming a promising new industry. In the 1980s, Japan, South Korea, the United States, Europe and other countries in the world already had professional polypeptide enterprises for industrialization. Communication and research topics involve biology, chemistry, pharmacy, food and many other industries related to peptides.
In Europe, America and Japan, a broad polypeptide market has been formed. There are two main products: one is polypeptide drugs and reagents, which have been listed in the world 100, which are very pure and expensive; The other is low antigen health food with active polypeptide as functional factor and common food containing polypeptide. The application of polypeptide in food (health food, nutritious food and common food) began in Japan in 1980s, and then polypeptide food was in the ascendant in developed countries such as the United States and Western Europe. At present, polypeptide food has formed an industry, and many famous companies have developed polypeptide food, polypeptide food additives and polypeptide factor series catering. As a high-tech product, functional peptides have been widely used in various foods. In Japan, the United States and Western Europe, healthy foods containing peptides emerge in an endless stream, including polypeptide drinks, polypeptide children's lunches, polypeptide old-age packages, polypeptide sports foods, foods for promoting calcium absorption, and antihypertensive foods.
Third, the development of peptides in China.
1September, 965 17, synthetic insulin was first discovered in China, which is also the first total synthesis in protein in the world. This achievement promoted the development of life science and opened the era of synthetic protein. The completion of this work is considered to be the most important achievement in the field of peptide and protein synthesis in 1960s, which greatly improved China's scientific reputation and played a positive role in promoting the research of protein and peptide synthesis in China. The synthesis of artificial bovine insulin marks a key step in the journey of understanding life and exploring the mystery of life, which has great significance and influence.
Although the research on peptides in China began in the 1950s, due to institutional reasons, the market-oriented application has been unable to be carried out, and the contradiction between scientific research and market has become a chronic disease. With the spring breeze of reform and opening up, it has become the dream and action of many people of insight to dissolve the barriers of ideological imprisonment and revitalize China through science and technology. 1996, the establishment of Wuhan Polypeptide Research Institute, founded by returning scientist Dr. Chen, became an important milestone in the development of polypeptide industry in China. Its establishment means that the world's leading experience in science, technology and service is linked to domestic scientific research achievements for many years. At the same time, it has opened up a new field of combining scientific research with the market and built a platform for communication with the world, which is an important symbol of full confidence in the future market and the maturity of the polypeptide industry. On the basis of high-starting point and high-level scientific research, it has made beneficial contributions to the development of high-tech polypeptide biology research in China, and laid a good foundation for China to create high-level biological development and participate in international competition in the field of biomedicine in the 2 1 century. Wuhan Institute of Peptide Substances is committed to the research, development and application of peptide substances; The concepts of "functional peptide" and "polypeptide nutrition" were popularized and introduced for the first time. In practice, the modern biological polypeptide technology is combined with the traditional pharmacology of China, and a unique technical platform for the research and application of "functional peptides" integrating eastern and western technologies with eastern culture is established. Relying on famous peptide research experts in the industry, establish extensive academic exchanges with famous scientific research institutions at home and abroad; Keep abreast of the latest trends and achievements of peptide research in the world today, so that your project topics, research methods and product development are always in the leading position in the world. Under the guidance of scientific innovation, the road of product innovation is getting wider and wider. At present, the Polypeptide Research Institute has completed the development of dozens of finished products and raw material powder products, such as Chinese medicine protein polypeptide series, plant protein polypeptide series, marine protein polypeptide series, food additive polypeptide series, seasoning additive polypeptide series and plant growth regulator polypeptide series. In the initial promotion of the market, gratifying achievements have been made, laying a solid foundation for healthy and sustainable development.
1998, under the leadership of Dr. Chen, Wuhan Polypeptide Research Institute developed the first bioprotein product in China-albumin polypeptide. Albumin polypeptide is a high-tech product developed by bioengineering technology according to the latest biological theory, which comprehensively adjusts the human immune system with a brand-new concept; Albumin polypeptide is a small molecule polypeptide made from ovalbumin by directional enzyme digestion technology, which is very similar to the amino acid sequence and composition of human serum protein. Its function is to supplement basic nutrition, improve blood quality, maintain cell vitality, regulate immune function, improve physical fitness and promote disease rehabilitation. It has wide applicability and good health care application prospect for people with weak constitution, low immunity and malnutrition. As the first excellent biological protein product in China, albumin polypeptide capsule passed the import license of the United States Federal Food and Drug Administration, becoming the first China biological product to enter the American market. Albumin polypeptide capsule 1999 was listed as the national spark project, the national torch project in 2000 and the top ten key high-tech industrialization projects in Wuhan in 2000. It is the first polypeptide health care product in China that has been approved to be named after the word "peptide" and industrialized, and it has been a great success in the market.
Market is the lifeline of enterprises and products. In the process of seeking market recognition, the scientists of Wuhan Peptide Research Institute have deeply realized that there are contradictions in the process of commercialization and marketization of products. One party is the inventor, producer and supplier of new products; They are brave in innovation, always standing at the forefront of science and technology, keenly aware of the potential needs of human beings, and firmly believe in the unique value and broad market prospects of new products; On the other hand, market demand and buyers generally know little about the relevant scientific knowledge, principle, utility, performance and characteristics of products, so it is difficult to generate demand for products. At the same time, due to the constraints of ideas, the limitation of funds and the inertia of using the original products, consumers lack sufficient motivation to explore the technical mysteries of products and their special functions on human life. Due to the continuous development and innovation of high technology to promote the advent of new products, there will be a situation that supply triggers demand instead of demand determines supply in today's market, which is completely different from the mode that traditional marketing theory emphasizes that supply is determined after studying market demand. The marketization process of new products depends more on the innovation of marketing model, which attaches great importance to knowledge, information and intelligence, and wins by knowledge and intelligence rather than experience and art in the increasingly fierce market competition.
In the era of biotechnology, health care products reflect their efficacy with bioactive components; The most important thing is extraction and synthesis technology. The transformation and release of polypeptide technology to the production field, the wide application of polypeptide in the market and the continuous expansion of polypeptide industry market put forward urgent requirements for the application of new technology and industrial production. Wuhan Tiantianhao Biological Products Co., Ltd. is an enterprise established under the guidance of the new marketing concept. Wuhan Tiantianhao Biological Products Co., Ltd., as the vanguard of polypeptide industry, undertakes the heavy responsibility of industrialization of scientific and technological projects. The operating characteristics of Tiantianhao Company are to develop production-driven mode and improve "service marketing" and "cooperative marketing". Take projects, brands, information and other resources as the link; Grasp product research and development, commissioned processing, franchising and other links; In marketing practice, adhere to customer-centered, let customers become participants in product development and production process, and jointly discuss the complete market solution of marketing projects; Focusing on scientific research, development, production and communication, we should flexibly grasp the application of cooperation, service, adaptation and innovation in marketing methods, devote ourselves to the promotion and service of the concept of "functional peptide", cultivate the extension of product chain and the maintenance of marketing network with science and technology, form an interest alliance system with customers, give full play to their respective advantages, seek common development and form a win-win situation.
After years of efforts, Tiantianhao Company has developed and built the first fully computer-controlled and multi-variety compatible polypeptide raw material production line in China, with an annual output of thousands of tons of various polypeptide raw materials. More than 80 sets of high-precision and precision equipment in the whole production line can be integrated through automatic control technology, which can complete continuous series production from raw materials to finished products; Meet the technical requirements of mass production, high speed and high quality. Polypeptide production line fully embodies the original design concept of Tiantianhao Company, with leading technology and stable product quality, which greatly enriches the connotation of polypeptide production technology. We can make full use of the leading polypeptide production technology of Wuhan Peptide Research Institute, such as enzyme digestion preparation, solid phase synthesis, membrane separation, purification and identification. It has the characteristics of high product purity, large preparation amount and controllable quality of synthesis steps. The success of automatic polypeptide production line further consolidated the leading position of Tiantianhao Company in the industry. The products produced have also become synonymous with high quality and become the technical standards reflecting the performance of polypeptide products in China. At the same time, Tiantianhao Company has built various production lines of capsules, tablets and powders that meet GMP standards, with an annual output of 2000 tons of various powders such as polypeptide protein powder and bovine colostrum powder. Various polypeptide raw materials can be widely used in medicines, common foods, health foods, special nutritious foods, chemical reagents, animal feed and food additives, functional additives, plant growth regulators, antioxidants and preservatives. And successfully formed a large-scale sales and influence in the domestic market and overseas markets.
Wuhan Tiantianhao Biological Products Co., Ltd. is a high-tech enterprise recognized by Hubei Province and Wuhan Municipal Government, and several projects have been approved by the national "Torch Plan" and "Spark Plan". Wuhan Tiantianhao Biological Products Co., Ltd. was accepted as the governing unit by china health care association because of its special contribution in polypeptide research and application, and the company was designated as the china health care association Polypeptide Research Base and the location of china health care association Polypeptide Branch. Dr. Chen, the chairman of the company, was elected as the deputy secretary-general of china health care association as the first representative of the business community, and also served as the president of china health care association Polypeptide Branch.
Fourth, the development prospect of polypeptide industry
The research and development of protein and polypeptide drugs and polypeptide health care products is the most active and fastest-growing part in the fields of biomedicine and medical care, and will also be one of the most promising industries in 2 1 century. However, the research and development of biotechnology drugs in China started late. At present, there are some phenomena, such as weak research and development power, high-tech genetic engineering drugs are mostly imitation and low-level repetition. In the national high-tech development plan, biotechnology products have always been one of the priority areas. In the process of product industrialization, protein polypeptide drugs are restricted by many factors, among which the study of pharmacokinetics is facing higher requirements. The main reasons are the special structure and small dosage of protein polypeptide drugs and the interference of a large number of similar substances in organisms. All these make the analysis method of this kind of drugs different from traditional drugs, which greatly increases the difficulty of detection. Due to the huge investment and long research and development cycle of polypeptide drugs, there is no polypeptide drug product with independent intellectual property rights in China at present, and the production of polypeptide reagents is also small-scale.
Polypeptide compounds exist widely in nature, and the research on peptides with certain biological activity has always been a main direction to develop new health care products. These peptides can improve human immunity, enhance disease resistance and maintain human health. With the rapid development of modern science and technology, the means of obtaining peptides from natural products are constantly improving. With the application of some new methods and new concepts, new peptides have been found for the prevention and treatment of diseases. At present, the application of polypeptide health care products and polypeptide foods in China is more and more extensive. Many enterprises set foot in the polypeptide industry and launched dozens of products, and the production has begun to take shape. Generally speaking, China's polypeptide industry is still in the initial stage of dispersion, small scale, chaotic product system and far from forming an industrial chain. It should be said that the domestic polypeptide product market is gradually forming, and there is a broad market prospect. Bioactive peptides will create a new world of healthy food with its unique health concept, brand-new scientific and technological connotation and good technical performance.
In 2000, Wuhan Tiantianhao Biological Products Co., Ltd. introduced Ziqing Jiangzhi Peptide Soft Capsule to the health care product market. Ziqing soft capsule is a perfect combination of soybean polypeptide and α -linolenic acid. Soybean polypeptide is a small molecule polypeptide separated and extracted by advanced complex enzyme engineering technology. It can promote the secretion of thyroid hormone, reduce the synthesis of liver cholesterol, and effectively prevent the intestinal tract from repeatedly absorbing lipid metabolites, thus achieving the effect of reducing blood lipid; α -linolenic acid is separated and purified from perilla frutescens, a traditional Chinese medicine, and is called a vascular scavenger. Has the functions of reducing the contents of cholesterol and triglyceride in blood and reducing blood viscosity. Soybean peptides combined with perilla oil have complementary functions and can effectively reduce blood lipid. The appearance of Ziqing soft capsule not only provides a brand-new lipid-lowering product with remarkable curative effect, but also provides an innovative way for modern science and technology to develop and apply traditional Chinese medicine resources. Ziqing Jiangzhi Peptide Soft Capsule is the second polypeptide health care product with polypeptide as raw material approved for industrialization in China.
In the 2 1 century, more and more polypeptide products have been put into the health care products market, such as: Leneng peptide wine, vitality peptide beverage, soybean peptide produced by Riyuexing and Du Qing, power source peptide, weight-reducing peptide, liver-protecting peptide and so on. Accompanied by various concepts with China characteristics, such as multifunctional peptide, vitality peptide, growth peptide and so on.
The popularity of a new health care product is successful or not, and it is impossible to rely solely on the momentum and loud voice; Only visible and tangible effects can be deeply rooted in people's hearts. Bioactive peptide is the product of the development of modern biotechnology, which embodies the hard work of scientific workers. The research and development of polypeptide health care products has very high scientific and technological requirements, and its application in health care products is only mastered by a few enterprises in China at present.
Looking forward to the future, we firmly believe that bioactive peptides will create a new world of health industry with its unique health concept, brand-new scientific and technological connotation and good technical performance.
Fifth, strengthen international cooperation and promote the development of polypeptide industry.
Cooperation promotes civilization progress and social development. The development of polypeptide industry is inseparable from a good international cooperation environment. Its sustainable development ability depends on its concept and system to a great extent, and its scientific goal can only be achieved through international cooperation and exchange. By participating in and hosting the Asia-Pacific Polypeptide Society and launching the Asia-Pacific Polypeptide Anti-tumor International Forum, Tiantianhao Company provided consumers and business decision makers with opportunities for understanding, exchange and technical cooperation, which also marked a great step forward in our international cooperation.
With the development of domestic and international markets and the deepening of people's understanding, the research of polypeptide technology is developing in a more macro, micro, comprehensive and extensive direction. In the new century, cross-border, regional and global technical exchanges and cooperation will greatly affect the development direction and process of polypeptide industry. We must face the challenges brought by the internationalization of investment and development, project evaluation and project coordination. With the expansion of research field and the development of information network, the scale, investment intensity and research methods of modern polypeptide biotechnology are gradually entering a new era in which only international cooperation can achieve all-round development, whether from the depth and breadth of research or from the organization and scale of production.
Tiantianhao Company is a pioneer in the polypeptide industry, with a big career and a wide range of services. We should undertake more obligations and responsibilities, promote the popularization and application of polypeptide technology, and build the economic development platform of related enterprises and the public service platform of industry associations. Through international cooperation, we can effectively expand our research capabilities, share the research results and development experience of the international scientific community, share a broad market, further master core technologies, and participate in the formulation of industry standards and norms, thus enhancing our ability to participate in international cooperation and competition and achieving leap-forward development. Through international cooperation, we can not only benefit from the international community, but also contribute to the scientific cause of mankind. Through international cooperation and exchange, more products and research projects will have the opportunity to enter the world stage, and our years of efforts will be known to more countries and people and benefit human society.
Extensive participation in international exchanges and cooperation will surely accelerate the development of polypeptide industry and achieve the goal of leap-forward development. Our domestic research institutions and enterprises should actively adapt to the new situation, strengthen their study, improve their own quality, and go all out to develop and grow together with the polypeptide cause!