Type 2 diabetes mellitus, also known as non-insulin-dependent diabetes mellitus, as its name implies, does not depend on insulin injection, but it needs to be treated with insulin for a certain period of time. Many patients have concerns about insulin therapy, fearing that once used, it will become? Dependence? Yes, whether the types of dependence are different in pathogenesis has nothing to do with the use of insulin.
Insulin is a hormone secreted by human body under normal circumstances, so it has no side effects such as damage to liver and kidney function, and is a very safe hypoglycemic drug.
Patients with type 2 diabetes mainly switch to insulin treatment under the following circumstances:
1, when oral hypoglycemic agents cannot effectively control blood sugar.
The premise of oral hypoglycemic drugs to control blood sugar is that there is a certain amount of insulin secretion in the body. It has been found that 50% patients with type 2 diabetes have been ill for more than 15 years. Due to the significant decline of islet function, insulin will eventually be chosen to effectively control blood sugar. Because many patients with type 2 diabetes have no obvious symptoms at the initial stage of onset, it takes many years to be diagnosed as diabetes, so many people have to switch to insulin after several years of diagnosis of diabetes.
2. There are serious complications. At this time, switching to insulin can better control blood sugar.
We know that one of the main causes of diabetic complications is poor long-term control of blood sugar, and insulin is the most physiological drug, which can lower blood sugar in a short time. In addition, a large number of studies also show that insulin itself can also delay the progress of vascular complications.
3. Patients with liver and kidney diseases
No matter what kind of oral hypoglycemic drugs, they are more or less metabolized by liver and kidney and can be excreted. If the liver and kidney function is not good, the drugs taken can not be excreted in time, resulting in continuous accumulation in the body, and serious side effects such as hypoglycemia will occur.
4. When a woman is pregnant
Most oral hypoglycemic drugs will enter the fetus through the placenta, which will have adverse effects on the baby, so it is the best choice to switch to insulin at this time.
5. Severe infection before and after operation.
When infected, the human body secretes a lot of substances? Eliminate pathogens and protect yourself? However, these substances may lead to an increase in blood sugar, making it difficult to control the originally stable blood sugar. At this time, insulin is needed to control blood sugar.
Antibiotics used for infection may have hepatorenal toxicity, such as streptomycin and rifampicin used for tuberculosis patients, and oral hypoglycemic drugs will be metabolized by liver and kidney. Switching to insulin at this time can avoid increasing the burden on liver and kidney and protect the function of liver and kidney.
Good blood sugar control is also needed during the operation to avoid postoperative infection, and insulin can also promote wound healing.
In short, patients with type 2 diabetes should not be afraid to turn to insulin therapy. Whether the condition of diabetes is serious is not whether insulin is used for treatment, but whether there are serious complications. Insulin therapy can control blood sugar safely and effectively, avoid or delay the occurrence and development of complications and improve the quality of life.