1. After surgery, chemotherapy, radiotherapy, interventional therapy, etc. The patient got better and was discharged. After leaving the hospital, his diet was normal, his weight was maintained at a normal level, he was free to urinate and defecate, and he was not tortured by the disease;
2, full of energy, no fatigue, can cope with light or even heavy physical labor;
3. With the passage of time, patients gradually accept their illness, regain their optimistic and open-minded mood, and have no obvious ideological burden.
4. Blood routine is normal after blood collection, and there is no bone marrow suppression reaction; Check that the liver function is normal and there is no obvious hypoproteinemia; Check whether the renal function is improved or normal; Check that the electrolyte has no electrolyte metabolism disorder; Monitor blood sugar, blood pressure, etc. Within the normal range; Tumor markers decreased or returned to normal after treatment;
5, check color ultrasound, CT, magnetic vibration, gastrointestinal endoscopy, etc. No obvious head, lung, liver and bone metastasis, no tumor recurrence in gastrointestinal tract; Or the primary tumor shrinks and does not spread before the lesion;
6. General situation: the vital signs are stable (body temperature, breathing, heartbeat, pulse and blood pressure are normal), the wound is healed well, the weight is maintained in the normal range without continuous reduction, and there is no local lymph node enlargement or metastasis.
The rehabilitation of cancer is a long process. After the treatment is improved, it will be reviewed once every three months in the first year, once every six months in the second year and once every year thereafter. If it does not recur within five years, it can be said that the possibility of cancer being cured is very high.
The rehabilitation of cancer is as long and complicated as the occurrence of cancer, which is why cancer is difficult to cure. Although cancer is difficult to cure, there are actually many cases of cancer cure. How can cancer get better and how can it be completely cured? Let's discuss it today.
1, the test result is normal.
Generally speaking, the process of cancer treatment is inseparable from blood tests, including blood routine, urine routine, thyroid and so on. If these test data are normal, the blood system is in a healthy state, and if the urine test results are normal and all the indicators remain in the normal range for a long time, it can be preliminarily judged that the cancer is under control.
There are also tumor markers and autoimmune disease detection. If these two items have no obvious changes for a long time and pass the test, it can be preliminarily judged that the cancer has been cured.
There are more than 100 kinds of cancer, and whether cancer is cured or not is also related to the type of cancer. If cancer cells are not detected at all during the treatment, it can be considered that cancer is cured. Under normal circumstances, the visceral function of cancer patients is normal after rehabilitation, and the indexes such as blood lipid and blood sugar are also normal for a long time.
2, affect the blood test stability or normal.
B-ultrasound, CT, MRI, PET-CT and ECT were all normal. At present, Mr. Hu has not found any new lesions, and the nodules are stable without enlargement or enlargement, which can indicate that his body has returned to normal.
Cancer patients can combine organic selenium. Studies have found that selenium has a wide range of effects on immune function. Appropriate selenium supplementation can not only enhance immunity, but also inhibit the proliferation and growth of cancer cells. Selenium also has the function of protecting cell membrane and preventing hepatocyte necrosis. With the deepening of research, more and more evidence shows that selenium has certain preventive and therapeutic effects on tumors. Selenium can change the metabolism of carcinogens. Animal experiments show that if selenium is contained in food, the chances of cancer cells reviving will be much lower after a part of uterus with cancer cells is removed. Selenium also has certain preventive and adjuvant therapeutic effects on tumors. Postoperative selenium supplementation can reduce the recurrence rate of cancer patients. Preoperative selenium supplementation tends to shrink tumor cells to varying degrees, and most patients have slow and stagnant tumor growth.
3. There are no related symptoms after reexamination.
Bleeding: Bleeding is one of the common symptoms of cancer patients. Tumor necrosis generally causes a small amount of local bleeding, but if the tumor erodes the surrounding blood vessels, it will cause serious bleeding, such as hematemesis, melena, vaginal bleeding, hematuria and blood in sputum.
Weight loss: One of the common symptoms of cancer patients is weight loss. If the patient loses weight for unknown reasons within a period of time, it is necessary to check whether the tumor has the possibility of recurrence.
Lymph node enlargement: Lymph is an important way of tumor metastasis. If the neck, mandible, clavicle fossa, armpit and groin are swollen, see a doctor in time.
Pain and fever: if metastasis occurs, the pain may be very obvious. The tumor directly infiltrates the nerve tissue or more tumors compress the lumen of the body, which may cause tissue necrosis or inflammation and show signs of pain. Tumor necrosis, tumor invading celiac plexus, tumor metabolites entering blood stream, tumor brain metastasis, etc. , can also cause a fever. Fever is a common symptom of patients.
4. There is no recurrence within five years.
Apart from radical cure, if there is still a tumor in the body after long-term treatment, but the tumor does not develop further, it can be maintained for a long time, as long as there is no recurrence or metastasis within 5 years after treatment until the death of the host or other reasons, which is also one of the criteria for cancer cure.
Whether cancer is getting better can be judged by the following indicators:
(1) Subjective symptoms of patients
Most early cancers have no symptoms, while middle and late cancers generally have obvious symptoms, such as pain, fever, loss of appetite, weight loss, abdominal pain, bloating and emaciation. After receiving treatment, the symptoms of patients can be obviously improved, such as pain relief or disappearance, mental and appetite increase, overeating, weight gain, abdominal pain, abdominal distension and so on.
(2) Physical examination
Some tumors can be found through physical examination, especially superficial tumors, such as breast cancer, thyroid cancer, rectal cancer, skin cancer and so on. Doctors can measure the size, texture and activity of tumors. Taking breast cancer as an example, if the treatment is effective, the tumor lump will become smaller or even disappear, the skin ulcer will heal, and the axillary lymph nodes will shrink or disappear. Physical examination can provide more objective results.
(3) Blood test
Some hematological indexes will change after cancer patients receive treatment. For example, there are anemia and hypoproteinemia before treatment, and anemia or hypoproteinemia will improve after effective treatment. If the tumor markers increase before treatment, if effective after treatment, the tumor markers will decrease or even return to normal.
(4) Image inspection
Imaging examination can provide more objective evidence, such as color Doppler ultrasound, CT, MRI, PET/CT and so on. These imaging examinations can measure the diameter, volume and number of tumors, whether there are new lesions, blood flow of lesions and so on. Cancer patients need regular review after receiving treatment.
(5) Pathological examination
Pathological examination is the gold standard. After receiving neoadjuvant radiotherapy and chemotherapy, if the treatment is effective, cancer patients will eventually need to be surgically removed, and the removed lesions will be sent to the pathology department. The doctor will observe how many cancer cells remain under the microscope. Some tumors can be completely killed after receiving radiotherapy and chemotherapy, which is called complete remission. If complete remission is achieved, the treatment effect is excellent, patients are sensitive to adjuvant therapy and the prognosis is good.
1 is the clinical symptoms of patients, such as headache, dizziness, nausea and vomiting. However, with the passage of time, the cancer condition has been effectively controlled, so these uncomfortable symptoms will gradually improve. It may even be in a state of disappearance. For example, it may be chest tightness, abdominal pain, abdominal distension and loss of appetite, so there is a trend of improvement after active treatment, so this may also be a sign that cancer is gradually improving.
The second point is to look at the overall state of the patient. Generally, cancer patients will have high internal friction, and appear listless, pale or emaciated, nervous, irritable, anxious and other symptoms. Then when the cancer is relatively controllable, the harm to the human body is relatively small, so in this case, the relevant state of the body will be significantly improved. For example, I am in good spirits, talkative, easy to talk with people, and my face is rosy and beautiful. Another is that my weight may gradually increase, my expression is relatively indifferent, and there is no obvious anxiety and depression. I also like to go out and talk to people and communicate with them. In many cases, such as these, it is also a sign of cancer improvement.
The third point is some imaging examination, which can be said to be a very necessary diagnostic method. Generally speaking, through certain imaging examination, we can see that many cancers will gradually shrink at least in the same volume, and no distant metastasis has been found. Some may even be in a state of disappearance, and no primary lesions can be found. So this is also very important. General examination methods include CT, nuclear magnetic resonance, gastrointestinal endoscopy, etc. This is the most common clinical examination method.
The fourth point is some hematological tests, which are also very common means, such as liver cancer. It is possible that the index of alpha-fetoprotein will gradually decrease or even become normal. In fact, this index is very, very much in clinic. It depends on what your primary disease is. Have your abnormal indicators changed since the review?
The fifth point is the most accurate surgical treatment. Sometimes it takes two or three operations. Then it is a very good phenomenon to take out pathological examination at this time to confirm that there is indeed a trend of deterioration or improvement than before.
In fact, there are many indicators to judge. As an ordinary person, it is most common to observe the clinical symptoms and overall physical condition of patients, and the rest must be judged by professional doctors.
I wish you all good health!
With cancer, the most worrying thing is that the condition is getting worse step by step. If active treatment is taken, everyone is expecting the disease to develop in a good direction, but how can we know that cancer is improving? Let's look at this problem.
When I saw the subject's question, I first remembered an elderly lung cancer patient I dealt with some time ago. I want to share her experience first to expose the evil of cancer.
Speaking of this lung cancer patient, the tumor was not small at the time of discovery, but no distant metastasis was found after general examination. After aggressive chemotherapy and targeted drug treatment, the examination found that the tumor was also shrinking. Just when the family was happy that the treatment was effective, distant brain metastasis was found in the fourth chemotherapy review.
So, in fact, we are sometimes helpless about cancer. Although we see that cancer is getting better, it is hard to hide its evil nature.
The purpose of sharing the above true stories is mainly to tell you that doctors usually comprehensively evaluate the treatment effect according to the patient's signs, examinations and other aspects, and should not take it lightly because of the short-term improvement of some indicators. Whenever you have cancer, you should never relax your vigilance and be confused by appearances.
But I'm not saying that cancer can't get better, because some cancers found in the early stage can be cured, and even some cancers found in the middle and late stage can improve the quality of life of patients and effectively prolong their lives through active treatment.
First, the symptoms get better.
This is the basis of disease improvement. If the symptoms are obviously improved through active treatment, the body will feel comfortable, which is an indicator of the improvement of the condition.
For cancer, most of them will bring obvious discomfort symptoms to the body, such as pain, bleeding, fatigue, loss of appetite, listlessness and so on. If these symptoms can be improved by active treatment, it is also one of the manifestations of improvement for the disease.
In the late stage of many malignant diseases, palliative care is the only way to treat cancer if you lose your own radiotherapy and chemotherapy. If we can reduce physical discomfort and improve the quality of life, it is a kind of progress.
In addition, the tumor disappears or shrinks.
If the early tumor has no distant metastasis, aggressive surgical treatment can even achieve the purpose of clinical cure. This is definitely a sign of progress.
If there is no chance of surgery, or through radiotherapy and chemotherapy, targeted drug therapy, immunotherapy and other treatment methods, the tumor no longer grows or shrinks, then this is also an indicator of tumor improvement.
This index is usually based on imaging examination, and the tumor is small and has no distant metastasis, which is an important index for improvement.
For solid malignant tumor diseases, the tumor completely disappeared after ultrasound, CT and other imaging examinations, and the time exceeded 1 month, which was judged as complete remission; However, after treatment, the tumor radius (or the sum of all lesion radii) decreased by more than 30% for more than 1 month, which can be said to be a partial remission of the disease.
Furthermore, according to the blood auxiliary examination.
Many tumor diseases bring organ function damage, such as anemia, liver function, renal function, electrolyte damage, etc. In addition, the index of tumor markers increases. However, if active treatment is taken, the laboratory indicators will gradually develop in a good direction. Then it is also a manifestation of the improvement of malignant tumor diseases.
Therefore, the improvement of cancer condition means that the symptoms, signs, blood and imaging tests of patients will develop in a good direction, and it is generally difficult to determine the change of the condition simply by changing an index.
First of all, we must maintain a relatively stable psychological state.
Correctly understand the disease, actively cooperate with doctors, and believe that you can overcome cancer. Especially for many patients, their families choose not to tell them about their illness, mainly because they are worried that the psychological burden of patients will increase.
In addition, actively adjust the diet.
Do a reasonable diet, balanced nutrition, eat more fresh vegetables and fruits, chew slowly as much as possible, do not overeat, and avoid eating spicy, spicy, salty, smoked products, moldy and other foods. Excessive consumption of these foods can easily lead to aggravation of the disease.
Besides, take part in exercise as much as possible.
If physical conditions permit, proper exercise is necessary, which can effectively improve the patient's weak constitution and increase the patient's immunity, so as to have more strength to compete with cancer.
Furthermore, create a good environmental atmosphere.
To live in a suitable environment, keep indoor air circulation and indoor humidity suitable, and don't stay in a closed room without sunshine for a long time. Family members should actively communicate with patients and take care of them. Sometimes the company and encouragement of family members give patients the courage and confidence to overcome the disease.
Furthermore, face the treatment positively.
The treatment of diseases is influenced by medical conditions, family conditions and subjective wishes, so it is necessary to cooperate with doctors as much as possible. And if there are some side effects due to treatment, don't be too careful, actively consult a doctor and actively overcome them.
Therefore, whether cancer patients get better or not depends on many aspects, and a comprehensive evaluation is often needed. If you unfortunately get a malignant tumor, you should face it with a positive attitude and actively cooperate with the treatment to maximize the therapeutic effect of the disease.
From what aspects can we see that cancer is slowly improving? It is generally evaluated by clinical examination, blood examination and imaging examination.
Some people will say that it costs a lot of money to check this and that. The doctor looked at it. Can you give me a result? There are two ways to treat tumors: symptomatic treatment and anti-tumor. After symptomatic treatment, the symptoms are relieved, but the tumor situation may not necessarily improve. In some respects, the doctor's physical examination is far less accurate than machine exploration.
① The examination of clinical symptoms and signs is mainly about asking symptoms and physical examination. In addition to symptomatic treatment and traditional Chinese medicine treatment, the relief of certain symptoms of patients should be the performance of improvement. For example, lung cancer cough is generally stubborn, dry cough, no phlegm, no cough and other drug intervention, only when the tumor becomes smaller will this result appear. There are also some symptoms, such as increased appetite, weight gain, improved physical condition, reduced nausea and vomiting, which may also be the improvement of the condition.
Some typical and obvious signs can be detected, such as some swollen lymph nodes and masses on the body surface, breathing sounds related to tumors in the lungs, masses touched in the abdomen, and tumors diagnosed by digital rectal examination. If these signs become smaller or alleviated, the condition will get better.
② Blood tumor markers are the most commonly used, convenient and need to be checked repeatedly in clinic. Their diagnostic function is only auxiliary, but their significance for disease monitoring is much greater, provided that tumor markers are related to tumors, one or more. Significantly reducing or maintaining within the reference value range is an indicator of disease improvement. For example, the preoperative CEA of colorectal cancer was above 35ng/ml, and there were hundreds of CEA, which decreased rapidly after operation, and some CEA was below 5ng/ml, indicating that surgery is very effective for cancer treatment. The faster the decrease, the greater the surgical effect.
The blood test of circulating tumor cells and circulating tumor DNA is called "liquid biopsy", which is a very objective index. At present, it is not perfect, and it is mostly used for the diagnosis and monitoring of advanced tumors, and will be widely used in clinic in the future.
③ Imaging ultrasound, CT and MRI are the three most commonly used methods for tumor reexamination. It is clear that the tumor is getting bigger and smaller, and the index is objective, which is also clinical evidence.
General symptoms, signs, blood and imaging examination will develop in a good direction. It is generally difficult to determine the change of the disease simply by the change of a certain index, such as symptoms, such as tumor markers, and comprehensive judgment is needed. I'm Dr. @ Liu Yongyi, thank you for reading! 628
Cancer patients should be evaluated after treatment! For example, non-small cell lung cancer, advanced chemotherapy with platinum! Generally, when we come to the hospital in the third cycle of chemotherapy, we must first evaluate the curative effect of the patients and then do the treatment. How to evaluate? Imaging evaluation is the most important method! It is usually necessary to review the chest CT and then compare it with the CT images before chemotherapy. For example, it used to be 4*4cm, but now it is only 2*2cm, and the maximum diameter of the tumor has been reduced by half! According to the RECIST evaluation standard, partial remission (PR) can be achieved, and the effect is good! Of course, you have to do superficial lymph nodes, head MR, abdominal ultrasound, adrenal ultrasound, urinary ultrasound, bone scan and so on. In fact, this review is similar to the first-time phased examination!
The other is to look at the changes of blood tumor markers. For non-small cell lung cancer, carcinoembryonic antigen CEA, CA 125, CA 153, Cyfra2 1 and NSE may decrease after chemotherapy. Among them, it is reported that the decreased expression level of these markers after chemotherapy is positively correlated with the curative effect! For example, in patients with adenocarcinoma, CEA can be greatly reduced or even normal after 2 cycles of chemotherapy.
The last one is the patient's clinical symptoms. For example, patients with lung cancer have chest pain, chest tightness and cough. If the treatment is effective and the tumor in the lung shrinks, then these symptoms will also be improved.
In short, doctors must consider comprehensiveness and comprehensiveness when evaluating the patient's condition! The specific indicators have also been mentioned above, so it's good that you know! Again, professional things are given to professional doctors! What you have to do is to check regularly according to the doctor's advice!
Draw blood before each chemotherapy, do B-ultrasound, and draw blood to see if the tumor markers are normal.
B-ultrasound can compare the size of each metastatic lesion. I have neck and clavicle metastases and left axillary lymph nodes, and the results of B-ultrasound are getting smaller every time.
Every two cycles, including CT and MRI, the results can be compared with their previous examination results.
When I first checked, CT showed that there was no metastasis in the right hilum, no pleural effusion and a small amount of pericardial effusion.
On the second review, the mediastinal lymph node enlargement was also reduced by about one centimeter, and both lungs were scattered in small nodules.
Cervical CT showed lymphatic metastasis in the first review and lymphadenopathy in the second review.
These things are getting better gradually, and you will feel something yourself, such as your appetite getting better, your physical strength recovering and you are full of energy.
Before, I couldn't eat. I eat very little every day. I feel full after eating a little. Later, I can eat. It's getting better.
Weak body, the most obvious performance is that you can't walk for a long time, and you will be particularly tired. Later, you can walk and even run. It's getting better.
My energy is getting stronger and stronger Reading books or mobile phones for a while will be a little tired. Many times, I will listen to books to kill boredom.
Not at all now. I can read, exercise, walk and run. I don't breathe, I don't feel tired, I don't feel tired. This is progress.
There are many methods to evaluate the curative effect of tumor after treatment, the most important of which is imaging evidence. For example, the criterion of RECIST for evaluating the curative effect of solid tumor is to measure the change of lesion size before and after treatment.
Common objective evaluation index: 1. Imaging examination, commonly used to enhance the vibration of CT or MRI: By comparing the CT or MRI films before and after treatment, the changes of cancer focus in the same place (primary focus or metastatic focus or lymph nodes) are measured, which are generally divided into complete remission (CR), partial remission (PR), focus stability (SD) and disease progression according to the changes.
2. Changes of tumor markers: such as tumor markers (CEA, CA 199, CA 125, etc. There were obvious abnormalities before treatment, and the tumor markers would gradually decrease after treatment, which indicated that the tumor treatment had a certain effect and the tumor load was reduced.
3. Changes in metabolic degree of functional imaging (PET/CT examination): Studies have shown that changes in SUV value can also reflect the therapeutic effect through functional imaging of PET/CT. If the SUV value after treatment is significantly lower than that before treatment, the treatment is effective.
4. objective symptoms are alleviated: if the original palpable mass becomes smaller or disappears; The hydrothorax and ascites decreased or even disappeared.
Changes in subjective feelings:
Taking preoperative radiotherapy and chemotherapy for rectal cancer as an example, many patients' symptoms improved significantly during or after treatment, such as stopping bloody stool, reducing defecation difficulties, reducing defecation times, reducing anal distension, and a few patients with good results can completely disappear;
Some patients with gastric cancer can basically return to normal eating after chemotherapy, and the feeling of fullness in the upper abdomen is obviously reduced.
With effective treatment, the patient's physical strength will gradually recover, and his sensory activity ability will be enhanced and his physical strength will recover.
After treatment, the patient will gradually gain weight as long as his appetite returns to normal. The prognosis is generally good.