Understand the method of lowering serum creatinine, and what foods can't be eaten?

Various primary and secondary causes of damage continue to act on the glomerulus for a long time, prompting local microcirculation disturbance of the glomerulus, causing damage to glomerular capillary endothelial cells, attracting inflammatory cells in blood circulation to infiltrate, releasing pathogenic inflammatory mediators, starting the process of renal fibrosis, prompting epithelial cells to be damaged, and mesangial cells to begin phenotypic transformation. When mesangial cells are damaged and contracted, the filtration area of glomerulus can be reduced and the filtration fraction can be reduced. At the same time, the damaged and transformed intrinsic cells will secrete and synthesize a series of ECM, which is not easily degraded by matrix metalloproteinases, and promote glomerulosclerosis and tubulointerstitial fibrosis, so that a large amount of creatinine can not leak into the blood circulation normally, which is one of the reasons for the high creatinine. Grading treatment of early nephropathy and reducing serum creatinine and urea nitrogen are the most important means to treat and prevent renal insufficiency.