What are the well-known foreign manufacturers of mass spectrometers? What about domestic ones?

How come no one answered this question? What are the well-known mass spectrometer manufacturers at home and abroad?

In recent years, the rapid development of science and technology, mass spectrometry in the instrument is the most favored up, yesterday, "mass spectrometry is what the ghost," has said the mass spectrometry is widely used in chemistry, chemical engineering, medical clinical testing, pharmaceutical research, environmental monitoring, etc., and its demand is very large in China, alone in the field of medical clinical testing, the mass spectrometry service end of the market is estimated to be as high as 12.5 billion blue ocean market. Newborn genetic screening, vitamin D testing, microbial diagnostics, pharmaceutical testing and other testing areas, corresponding to the market space of 2.2 billion yuan, 7.6 billion yuan, 2.1 billion yuan, 600 million yuan, however, nowadays there are many manufacturers of mass spectrometers, and the middle and low-end mass spectrometry homogenization is very serious is a big problem, will be classified by mass spectrometry instrument, which mainly includes tandem mass spectrometry (LC-MS/GC-MS), time-of-flight mass spectrometry ( MALDI-TOF), coupled mass spectrometry (ICP-MS), ion trap (QTOF MS), etc. Among them, triple quadrupole tandem mass spectrometry and time-of-flight mass spectrometry are the more widely used and demanded types of all types of mass spectrometry, and at the same time, the competition in the market is also the most intense.

The main brands in the mass spectrometry market currently include international brands such as Agilent, Danaher (AB SCIEX), PerkinElmer, Thermo Fisher, Bruker (BD cooperative agent), Waters, Mérieux (Shimadzu), etc., and domestic brands such as Shandong Insignia, Guangzhou Fenghua, Tianrui Instruments, Guangzhou Dare, Antu, Yi Xin Bochuang, Yi Cheng Mody, Rongzhi, Wo Xin, something analysis and so on. Below Ran recommends popular mass spectrometer manufacturers brands and products in the Chinese market.

Mérieux

BioMérieux was founded in 1963, and its diagnostic system consists of reagents, instruments and software designed around four strategic areas: infectious diseases, industrial microbiology control, cardiovascular disease and oncology.

Mérieux developed the VITEK MS, a fully automated microbial mass spectrometry (MS) system that utilizes MALDI-TOF technology to enable accurate species-level identification of bacteria in minutes, a database of 15,000 strains, and advanced classification algorithms that provide accurate diagnostic-level reporting.

The MALDI-TOF MS market has been dominated by both bioMérieux and Bruker, with shipments of the two approximating 1:1.Time is moving into 2018 and the biggest change in the market is that bioMérieux has dropped its price!

Last year's VITEK MS, which was generally priced at 2.7-2.9 million dollars per unit, has repeatedly been sold at 1.5 million dollars in 2018 bids, and the price cuts have been staggeringly hard and fast.

For Méliès price cuts, some industry insiders believe that "the price war has begun, microbial mass spectrometry may fall to within a million dollars within the year, do not sell this price is no business."

And I predict that the price cut is intended to occupy the Chinese microbiology mass spectrometry procurement market has increased dramatically, these purchasing units to the first-tier cities of the tertiary hospitals and CDCs around the main.

Bruker

Bruker, one of the world's leading analytical instrumentation companies, launched its first commercial MALDI-TOF mass spectrometer in 1992.

Bruker's latest MALDI-TOF and TOF/TOF MS mass spectrometer, a powerful tandem mass spectrometer built as a method for in-depth analysis of proteins, is renowned for its ultra-high performance, stability, and innovative design.

Shimadzu

Shimadzu, a renowned manufacturer of testing instruments, medical devices and industrial equipment, has been increasing its investment in the mass spectrometry market in recent years, and has successively launched a number of new products in the UFMS series, such as the quadrupole time-of-flight mass spectrometry LCMS-9030, the high-sensitivity triple quadrupole type GCMS-TQ8050, and the inductively coupled plasma mass spectrometry ICPMS-2030. Mass Spectrometry new products, according to statistics, Shimadzu's China mass spectrometer reached a thousand units sold in 2017.

Waters

Waters liquid chromatography and mass spectrometry products are favored by scientists around the world, and has been in the industry for more than 50 years, and has become one of the largest companies in the analytical instrument industry.

Waters' newest products, the Gas Chromatography-Mass Spectrometry/Mass Spectrometry (GC-MS/MS) system for food safety analysis and the Direct Analytical Mass Spectrometry (DAMS) system for rapid molecular fingerprinting of finished food products, raw materials, and semiprocessed products, have been developed to meet the diverse analytical needs of laboratories in food testing organizations, universities, and biomedical research institutions.

SCIEX

SCIEX is a leader in tandem mass spectrometry with 40 years of innovation in cutting-edge instrumentation, workflow solutions and support. The company has developed the 4500MD Series of mass spectrometers, a flexible LC-MS/MS platform that is a triple quadruple quadrupole mass spectrometer that outperforms the 3200MD system with superior sensitivity and faster data acquisition for high-confidence quantitative analysis.

The other 3200MD mass spectrometer system is an affordable benchtop platform where high sensitivity, low detection limits and high specificity result in better quality data (compared to conventional technologies), enabling a significant reduction in the time and cost required for routine clinical diagnostic testing.

Agilent

Agilent is a global leader in analytical laboratory technology with more than 40 years of expertise in mass spectrometry, with a focus on gas chromatography (GC/MS) and liquid chromatography (LC/MS) systems.

Agilent 6495B Triple Quadrupole Liquid Mass Spectrometry System

Yingsheng Bio

Yingsheng Bio was founded in 2009, and has built a one-stop mass spectrometry testing platform in the industry, including an artificial intelligence pre-processing platform, mass spectrometry high-throughput detection, cloud processing data analysis and so on. In 2013, we developed a newborn genetic metabolic disease screening kit based on tandem mass spectrometry platform, which is the first one in China; and in 2015, we developed a full-spectrum vitamin detection kit, which is exclusive in China.

On July 10, 2018, Insun Bio signed a strategic cooperation agreement with Thermo Fisher to establish a mass spectrometry medical equipment production base in Jinan, driving the localization of mass spectrometry equipment through complementary advantages.

Yixin Botron

Yixin Botron's in-flight mass spectrometry is the earliest instrument in China to get the registration certificate for Class II instruments, which has now been promoted to genetic testing, glucose-based testing and so on.

As the first clinical time-of-flight mass spectrometry company in China to obtain the CFDA registration certificate, YiXin is the first in the world to create and realize the multi-platform of a single machine, and has developed the world's only one-machine multi-purpose platform - Clin-TOF Time-of-Flight Mass Spectrometry System, which is the only one-machine multi-purpose platform in the world, and can satisfy the clinical applications of microorganisms, proteins, genes, and glycolysis in four major fields. One machine can fulfill the clinical applications in four major fields: microbiology, protein, gene, and glycosyl.

Currently, the system has built the world's first microbial mass spectrometry cloud center through a microbial mass spectrometry database of over 370 genera, 2,200 species, and 8,100 strains based on the Chinese flora, which has been clinically validated for over 200,000 strains.

AntoBio

Microbial testing is AntoBio's traditional second main business, the company relies mainly on the sales channels of existing products, the new entry into the microbial diagnostic market more quickly and effectively.

Anto's Autof MS 1000 is expected to become the domestic microbial database and clinical sample testing qualification at the same time microbial MALDI TOF clinical mass spectrometry, and in the original channel to rapidly release the volume.

In addition to these manufacturers, there are Wo Xin Mass Spectrometry, Tianrui Instruments and East West Analytical are specializing in mass spectrometry, not limited to flight mass spectrometry, as well as liquid phase, gas phase mass spectrometry, etc., the medical attributes are not very obvious.

Rongzhi biological is specialized in microbial detection to do flight mass spectrometry, but the three types of device registration certificate application is difficult and time-consuming, into the hospital's journey is still early, expect to start from the food microorganisms such as a low-threshold industry.

In the field of mass spectrometry, in addition to the above manufacturers, there are a number of agents and service providers, such as ODI Innovation exclusive agent of the U.S. JWT liquid chromatography mass spectrometry instrumentation and reagents, the company's Lin always has more than 20 years of experience in the old test people, I have asked him a lot of professional issues in the field of mass spectrometry.

Oudi Innovation

Jewack was founded in 2005, the United States, has a production base in Europe, the products are mainly involved in the LC-MS / MS and HPLC diagnostic test kits and the development of liquid chromatography system, but also includes mass spectrometry sample pre-treatment system and analytical software.

The Jetwak Multitasker mass spectrometry pre-processor is the world's first fully automated mass spectrometry processing instrument, which can be directly connected to mainstream liquid tandem mass spectrometers in the market, reducing the number of manual steps and realizing the automation of the whole process of mass spectrometry detection.

Dian Diagnostics

Dian Diagnostics signed a cooperation agreement with SCIEX, a mass spectrometry producer under Danaher, in 2017 and announced*** the establishment of a joint venture company, DISAIS Diagnostics, to collaborate on mass spectrometry technology in China's clinical promotion, among other aspects.

Diesel Diagnostics' first phase will focus on the development, registration, and marketing of in vitro diagnostic reagents/kits for use with Class I, II, and III instruments, as well as with the 4500MD or other Sciex instruments.

Golden Reach Medical

Golden Reach Medical is an early service provider in the field of mass spectrometry testing in China. The company gradually laid out the clinical testing of mass spectrometry in 2008, and about half of its laboratories can now provide mass spectrometry testing including newborn screening, vitamin D, and drug concentration testing.

The future of mass spectrometer manufacturers in brief?

Although the Chinese mass spectrometry market is a late starter compared to the North American and European markets, it has much more potential for growth. Unlike some domestic instruments that can be used to compete with imported instruments, mass spectrometry is still the weak link of domestic instruments. However, we are pleased to see that more and more domestic manufacturers are turning their attention to mass spectrometry and that the country is focusing more on mass spectrometry. We have reason to believe that domestic mass spectrometry will "break" foreign brands and take its place in the market. In the next ten years, China's mass spectrometry market will be "a fierce battle". In the end, who is the biggest winner, let's wait and see!

Reference: In Vitro Diagnostics