(1) Develop cutting-edge technologies to lead the development of medicine.
Seizing the development trend of the frontier fields of science and technology, taking the development of frontier technologies such as biology, information, materials, engineering, nano and so on as the forerunner, strengthening the cross-fertilization of multi-disciplines, vigorously pushing forward the transformation of frontier technologies into medical applications, and endeavoring to take the place in the international frontier fields of medical science and technology and lead the development of medical science and technology.
Development focus:
1. "Histology" technology. Develop genome, transcriptome, proteome, metabolome, epigenome, structural genome and other types of genomics technology, accelerate the development of next-generation sequencing technology, high-throughput sample analysis technology, micro-sample extraction and amplification technology, massive data analysis technology, etc., and promote the application of genomics technology in the prevention and control of diseases and clinical diagnosis and treatment.
2. Systems biology technology. Develop medical informatics, bioinformatics and computational biology technologies, research and development of high-throughput biomedical data analysis and text mining technologies, and construction of large-scale biomedical data fusion and analysis platforms to support the analysis of genomic structural variation and disease pathogenicity correlation analysis, epigenome and molecular typing of major diseases and other research.
3. Nanomedicine technology. Research on nanomedical materials, nanocarriers for drug delivery, nanobio-devices, nano-diagnostic reagents and other core key technologies and products; carry out research on the mechanism of biological effects and safety evaluation of nanomedical products.
4. Stem Cells and Regenerative Medicine Technology. Research on embryonic stem cells, adult stem cells, induced pluripotent stem cells (iPS) and other stem cell differentiation and development technology, as well as separation and identification, expansion, identification, implantation in the human body, immune rejection and other key technologies of stem cell therapy; research on tissue engineering medical products and preservation of regenerative medicine and other key technologies.
5. Medical engineering technology. The development of new electromagnetic function detection and analysis technology, high-resolution medical imaging technology, molecular biomedical diagnostic technology, medical implant/intervention body technology, based on multi-modal fusion image-mediated individualized surgical planning, navigation, positioning technology, and the combination of modern science and traditional medical theory of Chinese medicine biomedical engineering technology.
(ii) Emphasize basic research to solve scientific problems.
With the goal of solving the key scientific problems of human health and disease prevention and treatment, we will study and clarify the nature of the life process, explore the laws of disease occurrence and development, and y reveal the theoretical basis and scientific connotation of the understanding of life and disease in traditional medicine, and strive to make breakthroughs in the physiological and pathological process of life activities, the mechanism of disease occurrence and development, and the basic theoretical study of its prevention and control, and provide theoretical and technological basis for the treatment and prevention of disease and health promotion. and health promotion, and to provide a theoretical and technical basis for disease prevention and treatment.
Development focus:
1. Basic research on chronic non-communicable diseases. To carry out basic research on the prevention, diagnosis and treatment of chronic diseases such as cardiovascular and cerebrovascular diseases, malignant tumors, metabolic diseases, psychiatric and neurological diseases as well as immune diseases, to elucidate the etiology of the disease and its regression, and to study the molecular and cellular mechanisms of the pathogenic process, etc.
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2. Basic research on infectious diseases. Research on the epidemiological characteristics of infectious diseases, pathogenesis, diagnosis and treatment, and the basic scientific issues of vaccine and drug research and development, and the development of new strategies for monitoring, early warning, prevention, diagnosis and treatment of infectious diseases.
3. Basic research on individual development. Research on the spatio-temporal specific regulatory mechanism of gene expression, the mechanism of cell division, migration, apoptosis and other life phenomena occurring in the process of individual development and regeneration, the temporal regulatory mechanism of development, the use of model organisms and animal models to reenact and verify the individual genetic development mechanism, the molecular mechanism of infant and child intellectual development and the development of physiological and physical function, and so on.
4. Basic research on aging and aging-related diseases. Research on the control mechanism of aging and molecular regulation mechanism; aging and metabolic abnormalities and the relationship between biological rhythms; reproductive aging and menopausal syndrome prevention and treatment of basic research; aging and heart disease, tumors, degenerative diseases and other major diseases occurring in the relationship.
5. Basic research on brain science and cognitive science. Research on the cellular and molecular mechanism of brain function, the occurrence and development mechanism of major brain diseases, brain development, plasticity and the relationship between human intelligence, learning, memory and thinking and other advanced cognitive functions of the brain and its neural basis, brain information expression and brain information processing system, the human brain and computer dialog.
6. Basic research on human-environment interaction. Research on the effects of biological, chemical and physical factors and other harmful factors in the natural environment on the human organism and their mechanisms of action, clarification of the early biological effects of the relevant factors and the relationship with the development of diseases, research on biomarkers of environment-related diseases, etc., and the development of an early warning system for environment-related diseases.
7. Basic research on family planning and reproductive health. Research on reproduction and its regulation law; basic research on contraceptive pills, guiding drugs, biodegradable drug release system, anti-early and early pregnancy drugs and anti-pregnancy drugs; basic research on immuno-contraception; basic research on birth defects.
8. Basic research on disaster medicine. In response to natural disasters such as earthquakes, typhoons and floods, and man-made injuries such as transportation accidents, radioactive contamination and armed conflicts, it carries out research on the mechanism of trauma on the body and the body's pathophysiological response to trauma and the mechanism of adaptation; basic research on the mechanism of disaster-induced mental stress and its prevention and treatment; and basic research on the skills and equipments of emergency medicine.
9. Basic research on Chinese medicine. Carry out research on the basic theories of Chinese medicine, such as Tibetan phenomena, qi, blood, fluid and qi, etc.; carry out research on the scientific connotations of the authenticity of traditional Chinese medicine and the medicinal properties of traditional Chinese medicine; carry out in-depth research on the composition of formulas, components, ingredients, compounding and ratios, and reveal the scientific connotations of the theory of compounding of formulas; deepen the basic research on the traditional meridian prescriptions in conjunction with the clinic; carry out the basic theories of meridians and collaterals, meridian and collaterals function-related theories and the research on the mechanisms of the effect of acupuncture; carry out the basic research on the evidence of diseases and the rationale and method of prescriptions and medicines of Chinese medicine. The basic research on the disease evidence and the rationale and method of prescription and medicine.
10. Others. Basic research related to the creation of new drugs; research on the mechanism and prevention of diseases caused by nutrition, obesity, lifestyle, etc.; basic research on new methods, technologies and concepts related to medicine and health.
(3) Strengthening preventive research to reduce the risk of disease.
Implementing the strategic policy of "prevention first", comprehensively analyzing the impact of biological, environmental, psychological, social and behavioral factors on health, focusing on the development of risk assessment, early screening, prediction and early warning of diseases and comprehensive intervention techniques, accelerating the promotion of technical research on health measurement and health management, and moving forward the window of prevention and control of disease risk factors to achieve the goal of reducing the risk of diseases from the current level to the current level. It will move the window of prevention and control forward, realize the transformation from "treating the already sick" to "treating the not yet sick", and effectively reduce the risk and incidence of diseases.
Development focus:
1. Epidemiological research on diseases. To establish large-scale cohorts of key diseases such as cardiovascular and cerebrovascular diseases, malignant tumors, metabolic diseases, and psychiatric and neurological diseases, and large-scale cohorts based on the community population, to systematically monitor the incidence of key diseases in China and the changes in the spectrum of diseases, to explore the etiology of the diseases and their epidemiological patterns, and to provide a basis for the prevention and control of the diseases.
2. Research on health-related risk factors and risk assessment. It focuses on the research of health hazard monitoring and on-site detection technology of environmental chemical pollutants; air and water pollution evaluation technology; the impact of climate change on health hazards; on-site detection and high-throughput detection methods of food and drug safety; detection technology of occupational disease hazards, such as dust, radioactive substances, toxins and physical factors; and the risk factors related to local highly prevalent diseases.
3. Disease screening and prediction and early warning research. Focusing on strengthening the monitoring and early warning of chronic diseases and management, genetic susceptibility biomarker screening and identification research, accelerating the development of high-throughput, rapid, sensitive, specific and economical disease screening and prediction and early warning technologies, and improving the early detection of major diseases.
4. Research on early intervention techniques for diseases. Strengthen research on comprehensive intervention and new prevention and treatment measures for high-risk factors such as nutrition, environment, psychology, lifestyle and behavior, formulate and optimize three-level prevention programs for key diseases on the basis of scientific evaluation, and promote the promotion and application of effective prevention and treatment measures in different regions.
5. Research on key technologies for family planning and eugenics. It will strengthen research on the prevention and treatment of birth defects, comprehensively carry out research on key technologies for the identification of risk factors, risk assessment, monitoring and early warning as well as early intervention in the pre-pregnancy, pregnancy and childbirth periods as well as in infancy and childhood, and optimize and improve the overall technological plan for the three-level prevention of birth defects that is suitable for the Chinese population; it will also strengthen research on new contraceptive and birth control technologies that are safe, efficient and easy to use and on new technologies for preventing and treating infertility, and will set up a platform for the evaluation of family planning technologies to improve the level of reproductive health. reproductive health.
6. Health measurement and health management technologies. Focusing on the development of technologies for health data collection, individual health assessment, and monitoring of acute and chronic patients, it will carry out research on health indicators and commonly used test indicators of the Chinese population, overall multi-dimensional health measurement and assessment, low load/dynamic continuous human body parameter measurement, and technologies for recognizing and regulating the state of health; it will accelerate the construction of a management information system based on personal health records, and set up a nationwide health data management system and personal health service platform based on information technology and network technology. management system and personal health service platform based on information technology and network technology.
7. Research on subhealth evaluation and intervention. To carry out research on the comprehensive evaluation index system of China's subhealthy people, establish reference diagnostic standards for subhealth status, and carry out subhealth typing and categorization; to study the pattern of subhealth occurrence and development; and to comprehensively utilize drug therapies and non-drug therapies to carry out research on subhealth intervention strategies, so as to prevent the development of subhealth status into a disease state.
(4) Highlighting clinical transformation and improving diagnosis and treatment level.
Targeting malignant tumors, cardiovascular and cerebrovascular diseases, respiratory diseases, injuries and poisoning, digestive diseases, endocrine and metabolic diseases, genitourinary diseases, neuropsychiatric disorders, degenerative diseases of the elderly, autoimmune diseases, hematological disorders, infectious diseases, and diseases of the oral cavity, otorhinolaryngology, ophthalmology, and skin, as well as rare diseases, we will emphasize the characteristics of clinical medicine and give full play to the special diagnostic and therapeutic advantages of traditional Chinese medicine (TCM). (ethnomedicine), optimize the clinical research model, vigorously promote the development of translational medicine, develop a number of urgently needed breakthroughs in key clinical diagnostic and treatment technologies, form a number of diagnostic and treatment technology specifications based on scientific evaluation, and actively promote digital healthcare and the establishment of a regional healthcare service synergy model, so as to effectively solve practical clinical problems and optimize the healthcare service model.
Development focus:
1. Research on new diagnostic and treatment technologies. Focus on molecular diagnosis, immune diagnosis, diagnostic imaging, biological therapy, minimally invasive therapy, interventional therapy, physical therapy and other new diagnostic and therapeutic technology research, innovation in clinical diagnostic and therapeutic technology, improve the level of clinical diagnostic and therapeutic technology.
2. Appropriate technology research. Facing the rural areas and communities, research and screening of a number of safe, effective, economical and applicable health, traditional Chinese medicine, family planning and digital medical technology suitable for grass-roots application, and the establishment of an effective mode of popularization and application, so as to improve the technical level and service capacity of primary health care institutions.
3. Research on standardized diagnosis and treatment programs. Based on the results of evidence-based medical research, establish a system and method for scientific evaluation of medical technology, study standardized diagnosis and treatment programs and diagnosis and treatment paths, provide a scientific basis for disease classification and treatment, standardize medical behavior and improve the level of diagnosis and treatment services.
4. Individualized diagnosis and treatment technology research. Development of individualized diagnosis and treatment technology, the establishment of molecular typing standards for key diseases, according to individual differences in the study and formulation of individualized diagnosis and treatment programs; give full play to the traditional advantages of individualized diagnosis and treatment of traditional Chinese medicine, and strengthen the methodological research and clinical evaluation, improve the ability and level of traditional Chinese medicine diagnosis and treatment.
5. Digital medical technology research. Based on the standardization of medical information, it focuses on the development of medical information integration and fusion, electronic medical records, clinical information and decision-making support, personal health information management and monitoring and other technologies, strengthens the integration of data, information, knowledge and services, and promotes the integration of services and regional synergy among hospitals at different levels, optimizes the allocation of medical resources and improves the level of technical services, and boosts the implementation of medical reform.
6. Research on diagnosis and treatment technology of Chinese medicine (ethnic medicine). Strengthening the academic inheritance of famous and old Chinese medicine practitioners and ethnomedicine practitioners, organizing their experiences, as well as digitizing and preserving Chinese medicine (ethnomedicine) ancient literature; strengthening the construction of Chinese medicine's clinical evaluation system, strengthening the clinical research of Chinese medicine (ethnomedicine) and Chinese and Western medicine combined diagnostic and therapeutic techniques, and improving diagnostic and therapeutic effects; strengthening the research and screening of clinically appropriate techniques in Chinese medicine (ethnomedicine), and promoting the popularization of their application.
(5) Strengthening health care and rehabilitation, and serving the health of the entire population.
Centering on the demand for health care and rehabilitation, the program focuses on breaking through the health, conservation and psychological aspects of health care for the aging population, improving the health of women and children, improving the quality of life of people with disabilities and patients recovering from chronic illnesses, and carrying out research on popularization of public health technologies for the public's concern for health, so as to serve the improvement of the health of the entire population.
Development focus:
1. Health care for the elderly. Strengthen the assessment of the health status and self-care ability of the elderly population, the maintenance of vital organ function methods and techniques, elderly health monitoring and management, elderly life care nursing, the elderly hospice care technical support, the elderly applicable rehabilitation aids and other research and promotion; give full play to the strengths of traditional Chinese medicine, to carry out research on traditional Chinese medicine geriatrics.
2. Women's and children's health care. It carries out research on women's reproductive health care monitoring and promotion of technologies for preventing and treating diseases that seriously jeopardize women's health, such as breast cancer, cervical cancer, and infections of the reproductive system, so as to prevent and reduce the occurrence of common diseases among women; strengthens research on and promotion of technologies for preventing and treating serious diseases in infants and children, such as neonatal asphyxiation, children's pneumonia, diarrhea, and so on; strengthens research on children's mental health; and strengthens research on the monitoring of nutritional deficiencies in children and on intervention technologies.
3. Rehabilitation for the disabled and the chronically ill. Adoption of compensatory techniques for motor, visual, communication and other functions to enhance the rehabilitation level of the disabled; on the basis of strengthening acute treatment and control period rehabilitation, focusing on strengthening the capacity of rehabilitation treatment during the recovery period of chronic diseases, the mechanism of rehabilitation of traditional Chinese medicine and the promotion of appropriate technology.
4. Public health popularization technology. Systematic screening and collation of health knowledge and disease prevention technology, focusing on the development of disease prevention and treatment popularization technology, healthy life digital dissemination and popularization technology, scientific and rational use of medication popularization technology, etc., the establishment of a national health website, improve the health literacy of the whole population, and realize the transformation from passive medical treatment to active health.
(VI) Paying attention to public **** health and constructing safety barriers.
Strengthening the prevention and control of major infectious diseases and new outbreaks of mass unexplained diseases, improving the level of trauma care, perfecting the scientific and technological emergency response mechanism, upgrading the medical rescue capacity for natural disasters and other sudden public **** events, effectively responding to public **** health and safety issues such as major food safety, occupational health and biosafety, and improving the ability of prevention, control and emergency response to construct a barrier to protect the health and life safety of the people. The development of the health care system is a major step forward in the development of the health care system in China.
Development focus:
1. Prevention and control of infectious diseases. Focusing on major infectious diseases such as AIDS, viral hepatitis, tuberculosis, etc., carry out research on key technologies such as detection and diagnosis, monitoring and early warning, vaccine research and development, and clinical treatment, so as to effectively reduce the rates of new infections and deaths of AIDS, viral hepatitis, and tuberculosis, and to significantly enhance the capacity of emergency response, comprehensive prevention and control of major infectious diseases; at the same time, carry out research on prevention and control of other important infectious diseases such as new and sudden-onset infectious diseases, tropical diseases, parasites, and hand-foot-and-mouth diseases. Other important infectious diseases prevention and control research.
2. Medical emergency rescue. Improve the medical emergency rescue chain, strengthen the technical reserve, establish the system of medical emergency treatment of emergencies, pay attention to the psychological assessment of the survivors of the disaster and intervention research, and improve the level of medical emergency treatment of emergencies and trauma treatment.
3. Battle trauma treatment. Carry out research on the prevention and treatment of weapon injuries and battle wounds characterized by military medicine, field blood transfusion, and prevention and treatment of training injuries; carry out research on countermeasures for the treatment of injuries caused by traffic accidents; and develop new types of emergency treatment equipment.
4. Public **** health security. Carry out research on food safety and nutritional hygiene, environmental hazards and occupational health, biological safety, drug safety and other issues to effectively improve food safety, reduce occupational hazards, reduce the incidence of drug safety incidents, and safeguard biological safety.
(VII) Promoting health industry and economic development.
Taking major new drugs, medical devices, and modernization of traditional Chinese medicine as the core, developing strategic emerging industries in biomedicine, accelerating the cultivation of large health industries, improving the localization capacity of medium- and high-end medical products, upgrading the scale of the industry and its technological competitiveness, and providing industrial support for the improvement of the capacity of medical services while promoting economic development.
Development focus:
1. New drug research and development. In order to meet the basic needs of the people for medicines and to cultivate and develop the pharmaceutical industry, we will break through a number of key technologies and production processes for the creation of medicines, develop 30 innovative medicines, reform about 200 large varieties of medicines, improve the technology platform for the creation of new medicines and modernization of traditional Chinese medicine, build a number of strategic alliances for technological innovation in the pharmaceutical industry, basically form the national drug innovation system with Chinese characteristics, and enhance the independent research and development capability and industrial competitiveness of pharmaceutical enterprises. At the same time, it will strengthen the research on clinical trials of drugs, enhance the monitoring of adverse drug reactions, emphasize the development of orphan drugs and drugs for infants and young children, and satisfy the public's demand for drugs and ensure drug safety.
2. R&D of medical devices. Research on clinical application of large demand, wide application of China's urgent shortage of high-end diagnostic, therapeutic medical devices; vigorously promote the application of cost-effective medical equipment for primary health care institutions to develop, improve the degree of intelligence, technical stability and product reliability; research and development of easy to operate and use for family or personal self-care, functional rehabilitation and replacement of medical equipment products; combined with natural disasters, public **** health emergency and other scene of the incident. Public **** health incidents and other on-site rescue needs, research and development of emergency rescue equipment.
3. Modernization of traditional Chinese medicine. Focusing on Chinese medicine resources, quality control, efficacy evaluation, safety evaluation and adverse reaction monitoring, new formulations, clinical efficacy evaluation, production process control and other aspects of the key technology research; GAP planting base technology optimization and upgrading and large-scale promotion, to carry out research on the cultivation of rare and endangered traditional Chinese medicine resources and research on alternatives to strengthen the research on new types of traditional Chinese medicine tablets, as well as traditional Chinese medicine new dosage forms and new processes, to ensure the sustainable development of traditional Chinese medicine; to carry out the research on the development of the modernization of traditional Chinese medicine. To ensure the sustainable development of traditional Chinese medicine; to carry out the "secondary development" of traditional and famous Chinese medicines with precise efficacy, and to focus on strengthening the research and development of modern Chinese medicines with precise efficacy and relatively clear mechanism of action.
4. New health product development. Strengthen the research of functional food, health care products and new health products based on the theory of Chinese medicine and health care and diagnostic and treatment technology, to provide a number of health products for the improvement of public health.
(VIII) Improvement of the conditions of the platform to support the development of medicine.
In accordance with the needs of medical science and technology development, the construction of the medical science and technology innovation system will be systematically strengthened, scientific and technological resources in the field of medicine will be optimized and integrated, and a scientific and technological support system will be built up which is reasonably laid out and of international first-class standard, including key laboratories, engineering technology research centers, clinical/translational medicine research centers, medical cross-scientific research centers, and clinical collaborative research networks. It has established a perfect medical science and technology innovation system covering the whole process of basic research, applied research and development research, promoted the openness of medical science and technology resources, realized the large-scale integration of China's medical research resources, promoted the rapid development of medical science and technology, and laid the foundation for the generation of major research results in the field of medical science and technology.
Development focus:
1. New medical research centers. Relying on advantageous hospitals to build a number of clinical/translational medicine research centers, strengthen clinical medical research, promote two-way exchanges and interactions between basic medicine and clinical research, accelerate the transformation of cutting-edge technologies and basic medical research results into clinical applications, and improve the level of diagnostic and treatment technologies; relying on scientific research institutions and universities to build a number of medical cross-science research centers, including systematic biomedical research centers, biomedical engineering research centers, environmental health research centers, etc., and to build a new medical research center. Center for Systematic Biomedical Research, Biomedical Engineering Research Center, Environmental Health Research Center, etc., to promote the development of cross-disciplines, and provide support for the long-term development of China's medical science and technology industry and key breakthroughs.
2. Clinical collaborative research network. Further increase the integration of China's medical research resources, relying on clinical research bases, to create a number of interdisciplinary, cross-regional specialty clinical collaborative research network system, focusing on advantageous strengths, strengthen the top-level design, optimize the research process, the establishment of a new type of collaborative research and sustained promotion of research on the prevention and treatment of major diseases; through the clinical collaborative research network system, systematic construction of the clinical sample resource base, the disease registration Through the clinical collaborative research network system, systematically build a clinical sample resource database, a disease registration ****sharing platform, and a clinical research data resource and knowledge management center, strengthen the integration, consolidation, ****sharing, excavation and analysis of medical resources and diagnosis and treatment information, and set up a group of disease prevention and treatment research databanks with our country's characteristics from the occurrence, development, diagnosis and treatment of diseases to their prognosis, so as to realize the large-scale consolidation of medical research resources; and pay attention to the enhancement of the research platforms and capacity of medical ethics and evidence-based medical research. The construction of the platform and capacity of medical ethics and evidence-based medical research will be emphasized.
3. Large-scale cohort research bases. Focusing on strengthening the construction of preventive medicine research bases based on community populations, we will do a good job of overall layout and systematic design, build national large-scale cohorts with sustainable research features such as resourcefulness, refinement, histology, standardization, systematization, informatization, and integration, and construct supporting information databases and ****-enjoyment platforms, as well as form a long-term operation mechanism.
4. Medical science and technology information and strategic research platform. Integrate information resources in the fields of medical science and technology and life sciences, strengthen the construction of the medical science and technology data *** enjoyment platform, strengthen the processing of medical science and technology information, in-depth analysis and information product delivery capabilities, and provide information support for the promotion of the innovative development of medical science and technology; strengthen the strategic research in medical science and technology and health policy and management research, encourage the strategic research in the field of medical science and technology and the establishment of research institutes, and establish a strategic research in the field of medical science and technology, and the establishment of research institutes. It encourages the development of strategic research and health policy and management research in the field of medical science and technology, encourages the establishment of research institutes, establishes a pool of experts in strategic research and health policy research, grasps the direction and focus of medical science and technology in a forward-looking manner, and improves the capacity of macro-strategic planning and systematic design in the field of medical science and technology, as well as the capacity of scientific decision-making and efficient management.
5. Medical Laboratory Animal Platform. To systematically establish rich experimental animal strain resources and experimental animal gene mutant libraries; to accelerate the development of experimental mammal models of major diseases, to meet the needs of disease mechanisms, drug screening, clinical treatment research; to establish a domestic model animal breeding base, and to realize the preservation and large-scale supply of experimental animals and model animals.