Congenital stupidity or Down syndrome is an autosomal aberration and is the most common of the pediatric chromosomal disorders, which is also known as Down syndrome.
The child with the disease has wide eye spacing (along with upward slanting of the outside of the eyes), tongue-stretching-like, mental retardation, and through hand (only one horizontal line in the palm of the hand). The appearance of this particular face is still relatively good to judge, and doing the chromosomes will be more clear.
This kind of child is often accompanied by congenital heart disease (varying degrees of severity), as well as limb deformities and disabilities and other complications, because it is a chromosomal disease, at present, there is no cure possible.
Extended information:
Down syndrome is trisomy 21, also known as congenital stupidity or Down syndrome.
In 1866, Dr. John Langdon Down first described and published a complete description of the typical signs of Down syndrome, including the fact that such children have similar facial features, and in 1959 it was confirmed that Down syndrome is caused by a chromosomal abnormality.
Modern medicine has confirmed that the incidence of Down syndrome correlates with the age of the mother at conception, and that it is an abnormality of chromosome 21, with trisomy, translocation, and chimerism. Advanced maternal age and egg aging are important reasons for the occurrence of non-separation.
Often presenting with lethargy and feeding difficulties, their mental retardation manifests itself progressively with age, with an IQ of 25 to 50 and delayed motor and sexual development. Male Down's babies grow up to puberty and are not fertile. Female Down's babies grow up to have menstruation and are likely to have children.
Chromosomal karyotyping and the FISH technique are the primary laboratory testing techniques for Down syndrome. These two tests also have a positive impact on prognostic estimation of Down syndrome chimerism, as the phenotype of children with chimeric malformations is highly variable and can range from normal or near-normal to typical clinical presentations, and their prognosis is largely dependent on the percentage rate of normal cell lines in the child's somatic cells.
There is no effective treatment. The best means is to terminate the pregnancy before the expectant mother gives birth.
Baidu Encyclopedia - Pediatric Down Syndrome