According to the test and evaluation of multi-equipment clinical samples, the sensitivity and specificity of the reagent used in clinical detection are 88.66% and 90.63%. The sensitivity of IgM-IgG binding antibody test is much higher than that of IgM or IgG monoclonal antibody test (94.83% vs 1.72% and 3.45%). In addition, the results of antibody detection reagents were compared with fingertip blood and venous blood, and it was found that the consistency of the two tests was basically the same. It is suggested that POCT use the rapid detection kit of sars-cov-2igm-igg binding antibody. You can take blood with your fingertips at the bedside for examination, which is the first convenient screening method.
The first unit of this paper is a research team composed of Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Nanjing Second Hospital, Hunan Provincial Center for Disease Control and Prevention, and Jiangsu Ke Mei Medical Technology Co., Ltd. Zhong Nanshan first introduced the basic characteristics of this new epidemic virus, including its gene sequence, the nature of human-to-human transmission and various transmission routes. Speaking of detecting novel coronavirus, Zhong Nanshan introduced the rapid IgM (immunoglobulin M) test paper developed by the team as an auxiliary means of nucleic acid detection.
He also introduced the application of isothermal amplification chip, which can help inspectors to distinguish novel coronavirus, influenza A virus and influenza B virus. According to the condition of some newly cured patients with coronary heart disease in Fuyang, Zhong Nanshan thinks that the IgG antibody content of the cured patients has greatly increased. In this case, the test results are unlikely to be attributed to the recurrence of Fuyang A virus. It is not clear whether the nucleic acid test of Fuyang patients is still contagious. Zhong Nanshan suggested that the medical staff should continue the isolation examination after discharge.