I (48 years old) was diagnosed with adenocarcinoma of the lower end of the bile duct in April this year in Henan Provincial People's Hospital, and underwent pancreaticoduodenectomy, and liver metastas

I (48 years old) was diagnosed with adenocarcinoma of the lower end of the bile duct in April this year in Henan Provincial People's Hospital, and underwent pancreaticoduodenectomy, and liver metastasis was found in the review in September, and I did a... Based on your description, I deduce that the pathology at that time should be middle and low differentiated adenocarcinoma, with higher degree of malignancy, so the metastasis occurred faster. According to the international guidelines, you can have about 6 cycles of chemotherapy with Kenzei + cisplatin or oxaliplatin or S1 after recovery from surgery, which you also did not have. Now with liver metastases, the opportunity for surgery has theoretically been lost, and even if the liver metastases were treated, there would be no benefit to your overall disease-free survival time or overall survival time.

These chemotherapeutic regimens I just mentioned can still be performed now, but the efficiency is not fully guaranteed, and internationally only 20-30% of patients are effective, but the prolonged survival time is not ideal. No matter what kind of hospital, don't believe in one doctor's words, or understand that the tumor is a systemic disease, not the people think that if you cut it cleanly, you can cure it, you can prolong your life, and it won't recur. For cholangiocarcinoma, duodenal carcinoma, pancreatic head carcinoma, these diseases need pancreaticoduodenectomy, and the malignant degree is very high. Once liver metastasis occurs, it should never be operated, it should be treated conservatively (chemotherapy, targeted), and you can read the international NCCN guidelines. So, instead of continuing to stare at the lesions on the liver and simply seeking treatment for the liver, you should now understand that the tumor is already advanced and should be treated aggressively and conservatively (chemotherapy, radiotherapy) and so on.

If you really want to see it, you should go to Peking University Cancer Hospital (West Tumor) and Academy of Medical Sciences Cancer Hospital (East Tumor), and I believe it is similar to what I said. It should be chemotherapy + observation, plus radiotherapy if you are aggressive.