Working principle of electrochemical biosensor

Electrochemical biosensors

Electrochemical biosensors, as the earliest type of biosensors, mainly use solid electrodes as the base electrode, and fix the bioactivity as the molecular identifier on the electrode surface, and then the target molecules are captured on the electrode surface through the specific recognition between the biomolecules. The base electrode converts the concentration signal into a measurable electrical signal such as potential, current, resistance or capacitance as a response signal, thus realizing quantitative or qualitative analysis of the target analyte. >Ion Selective Electrode: Ion Selective Electrode is a kind of electrode with selective response to specific cations or anions, which has the advantages of fast, sensitive, reliable and inexpensive, etc. It is often used directly in the field of biomedicine. In the field of biomedicine, it is often used to directly determine some components in body fluids (e.g. H+, K+, Na+, Ca2+, etc.).

Redox electrodes: Redox electrodes are another type of potentiometric electrode different from ion-selective electrodes. Here the reference is mainly to the zero type of electrodes.

Current electrode

Oxygen electrode: there are a number of enzymes, especially a variety of oxidative enzymes and oxygenases in the catalytic reaction of the substrate to be used as an auxiliary reagent of dissolved oxygen, the amount of oxygen consumed in the reaction to determine the oxygen electrode. In addition, in the microbial electrode, immuno-electrode and other biosensors are also commonly used oxygen electrode as a signal converter, so the oxygen electrode is widely used in biosensors.