Within 3 months before the expiration of the validity period, the applicant shall make an application for re-registration in accordance with the original application for dispensing procedures and submit relevant information. Provinces, autonomous regions, municipalities directly under the Central (food) Drug Administration shall, within 30 days after accepting the re-registration application to make a decision on whether to approve the re-registration. This ensures that the quality and safety of the preparations of medical institutions are continuously regulated and controlled.