Project Declaration Guidelines for 2015
Important Supporting Directions
Agricultural Sciences
1. Molecular Mechanisms of Photosynthesis and Selection of Crops with High Light Efficiency Varieties
In response to the need to improve the efficiency of photosynthesis in crops, we will focus on the molecular mechanisms of efficient utilization of light energy by photosynthetic system, regulation mechanisms of photosynthetic product distribution and transport, carbon metabolism of C3 and C4 plants, and carbon metabolism of C4 plants. C4 plants as materials, focusing on the research of the molecular mechanism of photosynthesis system for the efficient use of light energy, the mechanism of photosynthetically active product distribution and transportation, the mechanism of carbon metabolism and photorespiration of C3 and C4 plants, the molecular basis of the formation of special anatomical structure of C4 plants, to obtain new materials and new lines of major food crops with significantly improved light energy utilization efficiency, and provide theoretical guidance and technical methods for the genetic improvement of crops with high light efficiency and the practice of breeding. This will provide theoretical guidance and technical methods for the genetic improvement and breeding practice of crops with high light efficiency.
2. Genetic Improvement of Important Economic Crops such as Oilseed Rape or Potato
Using oilseed rape or potato (potato and sweet potato) as the materials, carry out research on the breeding of high-yield and high-quality traits of important economic crops. Research on key genes and their regulatory networks affecting high oil content traits in oilseed rape, the relationship between photosynthesis products and oil accumulation, and the influence of environment and fertility period on oil accumulation, to provide theoretical guidance for breeding and production of high oil content in oilseed rape; research on key genes related to high-yield, disease-resistant, drought-resistant and other traits in potato and sweet potato, elucidating the regulatory mechanisms of tuber and root development, starch synthesis and accumulation, to provide guidance for the design and breeding of high-yield and high-quality varieties of potato and sweet potato. This will provide scientific guidance for the design and breeding of high-yield and high-quality potato and sweet potato varieties with multiple resistance.
3. Research on the expansion of breeding and healthy breeding of important agricultural animals
In response to the demand for the expansion of breeding and healthy breeding of domestic animals, we will systematically study the reproductive biological characteristics of sheep and goats from the perspective of their different breed resources, physiology and genetic regulation, and put forward the theories and measures to improve the fertility of sheep and goats; and we will also study the pathogenesis and transmission pathways of parasitic diseases that jeopardize the production of livestock and propose effective prevention and control measures. For parasitic diseases that jeopardize livestock production, we will study their pathogenesis and transmission pathways and put forward effective prevention and control measures.
4. Principles of matching the structure of high-yield crop groups with climate, soil and other ecological factors and regulatory mechanisms
For the formation of high-yield crop group structure and the efficient utilization of resources, the focus of the study: the structure of the crop group with the function of climate, soil and other ecological factors and the principle of matching the mechanism of regulation; high-yield and efficient crop production system of the aboveground groups and the underground root system, the root of microorganisms and soil nutrient water conditions, the mechanism of interaction between the aboveground groups and soil nutrient water conditions. The research focuses on the interactions between aboveground groups of high-yield and high-efficiency crop production systems and underground root systems, inter-root microorganisms and soil nutrient and water conditions; the characteristics and evolution of soil microbiota in high-yield farmland; and the constraints on high-yield and high-efficiency of the future large-scale production of China's main grain producing areas, so as to enhance the productivity of China's farmland and put forward feasible measures and policy recommendations.
5. Basic Research on New Agricultural Microbial Preparations
In response to the demand for optimization and upgrading of agricultural microbial preparations, we will carry out basic research on the sensing of agricultural microbial communities, elucidating the signal composition and conduction pathways of the new microbial communication system and designing highly efficient microbial formulations; and further elucidating the mechanism of microbial biocontrol preparation synthesis and ecological regulation. To provide scientific basis for the design of efficient, fast-acting, effective and multi-functional microbial preparations.
6. Biological basis for breeding fast-growing, high-quality and stress-resistant strains of important afforestation species or bamboo (Category C)
For the major afforestation species or bamboo, focusing on the study of the genetic basis of growth cycle regulation and fast-growing traits, as well as the molecular mechanism of adaptation to and resistance to adverse environments; the study of fixation of the excellent traits of afforestation species and the super strains of the varieties of the breeding pathway, and the establishment of the methods and techniques of large-scale breeding. The researchers will study the fixation of excellent traits of afforestation tree species and the way to breed super strains, and establish the methods and techniques of large-scale breeding.
7. Research on sustainable breeding of poultry or important aquatic species (Class C)
In response to the demand for sustainable development of intensive poultry and aquaculture, systematic research on the principle of regulating the uptake and deposition of nitrogen and phosphorus in poultry will be conducted, and effective ways of efficiently utilizing feedstuffs for nitrogen and phosphorus will be proposed, so as to establish a new mode of efficient, food-saving and clean production of poultry breeding; taking 1-2 important aquatic species as the object, comprehensive research on the breeding methods in controllable waters will be conducted, and the research will be conducted in the form of a comprehensive study on the development of the new mode. In order to provide a basis for further expanding sustainable aquaculture in natural water bodies, we will conduct comprehensive research on key aspects of biological issues such as nutritional requirements, disease prevention and control, environmental effects and product safety of aquaculture in controlled water bodies, and put forward standardized modes of aquaculture for related species.
8. Artificial grassland function regulation research (Class C)
For the development of high-quality and high-efficiency artificial grassland, improve the comprehensive productivity of China's grassland animal husbandry needs, focusing on the study of the zonal distribution pattern of artificial grassland and the design of spatial configuration, the formation mechanism of artificial grassland productivity and regulation of the pathway, the association of pasture production and livestock rearing system integration and the production of coupled with the belt, for the country to develop It will provide important scientific basis for the national development strategy of artificial grassland.
Field of Energy Science
1. Seepage Theory and New Methods for Improving Recovery Rate in Low-Permeability and Tight Oil and Gas Development
To address the major needs of efficient development and recovery rate improvement in low-permeability and tight oil and gas, research on the fine characterization and prediction of low-permeability matrix - fracture systems and other complex reservoirs, develop non-linear seepage theory, establish the theoretical basis for efficient development of low-permeability and tight oil and gas reservoirs, and research on the improvement of low-permeability and tight oil and gas reservoirs, as well as develop the theory and methodology for the development of low-permeability oil and gas reservoirs.
2. Voltage source type high-voltage multi-terminal DC transmission equipment and systems
For voltage source type high-voltage multi-terminal DC transmission, research on the mathematical model of the system, simulation methods and control laws; research on new topology of high-voltage DC converter, multi-converter interaction mechanism and interaction with the system; research on the limitation and disconnection mechanism of the short-circuit current in the high-voltage DC circuit breaker with different topology.
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3. Research on new high-performance secondary batteries
The research focuses on the theory of multi-electron reaction system of lithium metal and other light element compounds and the research on new, high-efficiency battery energy storage, focusing on breakthroughs related to ion-conducting membrane materials and high-efficiency, safe electrolyte materials, high-performance catalytic materials, and controllable preparation of nanostructured electrode materials of carbon nanostructures, to build a new system of new, high-capacity secondary batteries, and to realize new battery safety and industrialized applications. Realize the safety of new batteries and industrial applications to provide scientific support.
4. Theory and Methods of Safe and Efficient Drilling and Completion of Deepwater Oil and Gas Wells
Aiming at the major engineering problems of safe and efficient drilling and completion of deepwater wells in the South China Sea, we will research on the mechanism of geologic hazards and prediction models of deepwater drilling, the dynamics and safety control principles of complex load coupling between submarine wellheads, watertubes, platforms and the marine environment, and the mechanisms for well wall stabilization and wellbore pressure control under low temperature and high pressure, and establish and perfect the mechanisms for safe and efficient drilling and completion of deepwater wells in the sea.
To establish and improve the theory of safe and efficient drilling and completion engineering for deepwater offshore wells and to develop related advanced methods.
5. Basic Research on Scale Energy Storage and Heat Storage Processes (Category C)
For compressed gas energy storage, research on the flow heat transfer characteristics of supercritical gas and process coupling of energy transfer and loss characteristics, research on the internal flow structure of high-load compressor and expander, as well as the system debugging and optimization algorithms; for high-efficiency heat storage materials, units and systems, research on the convection and fluid-solid coupling heat transfer mechanism of heat storage materials performance.
In order to solve the problem of high efficiency heat storage materials, we will study the convection and fluid-solid coupling heat transfer mechanism, solve the problem of high efficiency heat storage and release characteristics of medium and high temperature heat storage materials, as well as multi-scale multi-phase heat transfer mechanism.
6. Typical process industry optimization and energy saving (Class C)
Typical process industry as the object of research, to achieve simulation-based process optimization design, regulation, amplification and enhancement, the study of process coupling, the realization of multi-level utilization of energy to improve the efficiency of energy use and reduce the impact on the environment; for the energy saving of inorganic membrane high-efficiency separation technology for process industry, focusing on the study of the control of material microstructure, membrane formation mechanism and membrane separation technology. For inorganic membrane high-efficiency separation technology in energy-saving process industry, we focus on the research of material microstructure control method, membrane formation mechanism and membrane separation mechanism, and establish the theoretical basis for the design and integration of high-efficiency membrane materials and large-scale membrane modules.
7. Research on scientific problems of efficient and clean utilization of energy power system
Focusing on the energy conversion efficiency of coal-fired power generation system, the research on new theories and methods to improve energy efficiency of energy power system; the research on new ideas of efficient utilization at different levels of the process equipment, system flow, thermal cycle, etc.; the research on the key scientific problems of efficient thermodynamic conversion of high-parameter power generation system and the efficient combustion of fuel in the high-parameter power generation system and the efficient combustion of fuel in the high-parameter power generation system. The key scientific issues of high-efficiency thermodynamic conversion in high-parameter power generation systems and high-efficiency combustion of fuels and pollutant control mechanisms in high-parameter power generation systems are studied.
8. Scientific Scale Exploitation of Coal and Protection of Water Resources in Ecologically Fragile Areas in Western China (Category C)
Focusing on the significant impact of large-scale coal mining on the ecological environment, especially water resources, in arid and semi-arid areas in western China, the research will study the dynamic changes and coupling relationship between the structure of the coal bedrock and the earth's stress field and the groundwater system under large-scale mechanized mining of coal and establish the relationship between the structure of the coal bedrock and the groundwater system under large-scale mechanized mining, so as to establish a scientific scale exploitation of coal in western China. new theory of scientific scale mining of coal in western China.
Field of Information Science
1. Synergistic Theory and Methods of Network Communication and Computing
In the face of the contradiction between the application of mobile Internet, information-physical fusion system (Cyber-Physical System) and big data and the bottleneck of communication, we will study the synergistic mechanism between the communication ability and the computation ability, the fusion theory of physical and cognitive, heterogeneous We also study the mechanism of collaboration between communication capability and computing capability, the theory of physical and cognitive convergence, heterogeneous networking and routing algorithms, the method of adapting to the diversity of spatial and temporal distribution of services and the on-demand regulation of multiple resources based on virtualization, and propose the model of collaboration of computational communication and the upper limit of the network gain that can be obtained, as well as completing experimental verification.
2. Computational theory and experimental research on advanced human-computer interaction
Research on brain-computer computation and interaction, including visual, auditory, tactile and other perceptions of the computation and interaction, emotional computation and interaction, action computation and interaction, the measurement of the human body parameters and cognition, research on the relevant theoretical models, sensor devices, transmission methods, data processing algorithms and experimental verification.
3. Efficient Representation and Processing of Image and Video Data
To study the visual computing model based on the mechanism of human vision for the storage, management, and processing of networked image and video data; and to explore the new theories and methods for the efficient representation, coding, transmission, analysis, understanding, and processing of large-scale image and video data in the networked environment.030600.net. Oriented towards an important application area, research on the theory, methods and efficient algorithms for the hybrid presentation of real field and virtual landscape.
4. Original research on new information devices with important application prospects
Carry out research on nano resolution fast optical imaging devices and technologies, and research on scientific issues such as breaking through the diffraction limit, near-field vector beam modulation, fast signal conversion and detection, and dynamic information acquisition and characterization; and research on the design theory of scalable flexible inorganic electronic devices, the realization of the transfer and the interface mechanism; Carry out research on new memory devices and avalanche photodiode (APD) single-photon detector devices, study the physical mechanism of amnesia devices, new material systems and device structures, and research on new mechanisms to improve the optical storage density and lifetime.
5. New biochemical microsensor system research
For the detection of persistent organic pollutants and certain heavy metals trace pollutants major needs, research on new biochemical microsensors integrated autonomy system, the main study of difficult to degrade biochemical pollutants of the new sensitive mechanism, trace biochemical enrichment mechanism and pre-treatment methods, low-dimensional nano-catalytic reaction mechanism and methods, sensitive materials, self-transmission, and the mechanism and methods of the new sensitive materials, and the new mechanism and methods of multi-transmission. The mechanism and method of low-dimensional nanocatalytic reaction, the mechanism and method of sensitive material self-renewal and the integration of multi-sensing unit autonomy and other scientific issues, to realize the rapid, online, automatic monitoring of trace biochemical pollutants.
6. Principles and Methods of Software Development Based on Open Source Code (C)
Focusing on the national needs of developing software service industry, the research will study the principles and methods of software development based on open source code; explore the model and methods of software development and maintenance based on group intelligence; analyze the law of formation and development of open source community; explore the mechanism of discovering and repairing software security defects based on open source code; study the model and methods of software development and maintenance based on open source code; and analyze the mechanism of discovering and repairing software security defects based on open source code. It also analyzes the formation and development of open source community; explores the mechanism of discovering and repairing the security defects of software based on open source code; researches the perception mechanism of the running state of software based on open source code and the method of guaranteeing the quality of service; and builds the experimental platform of software development and operation based on open source code.
7. Computational Theory and Methods of Urban Big Data (Category C)
Focusing on the field of public **** security and the actual needs of smart cities, research on the collaborative representation of spatial information data, social network data, etc., research on the theory of collaborative perception and group intelligence cognition for the three-dimensional space of the information space, the physical world, and the human society, put forward the visual computation model, establish the depth computation model, research on the virtual interaction and intelligent interaction in the three-dimensional space, and establish the depth computation model. Research on the new mode of virtual interaction and intelligent control of the three-dimensional space, to adapt to the needs of social management, smart city and industrialized production and other aspects of the application.
8. Theory of Information Transmission in Deep Space Environment (Category C)
Facing the needs of future deep space communication and exploration, research on coding theory of deep space network, exploring the dynamic boundary of the information transmission capability under the strong constraints of space-time and space-time on the interplanetary scale, researching on the joint and optimal utilization of multi-dimensional sparse resources in space, proposing the interplanetary communication technological system and architecture, analyzing the key problems, and setting up the experimental model. modeling.
Resource and Environmental Sciences
1. Compound Mineralization System and its Deep Driving Mechanism in Some Typical Areas (Belts) of China's Tertiary Tectonics-Mineralization Domain
We will select some typical areas (belts) of China's Tertiary Tectonics-Mineralization Domain, focus on the formation and evolution of the compound mineralization system, as well as its control of the formation of the country's urgent metal minerals, and study the evolution process of the compound mineralization system and the metal supernormalization mechanism in some representative areas. The evolutionary process of the composite mineralization system and the mechanism of metal supernormal enrichment, study the tectonic superposition and conversion process of the formation of the composite mineralization system, and explore the possible deep driving mechanism, so as to theoretically improve the foreseeability and purposefulness of the search for and exploration of the national urgently needed minerals, especially the large-sized -super-large deposits.
2. Spatial and temporal coupling process of water and soil elements in mountainous areas, their effects and regulation
To study the spatial and temporal coupling process of water and soil elements in typical mountainous areas in China and their resource and ecological effects; to analyze the thresholds of carrying capacity of spatial and temporal matches of water and soil resources at multi-scales; to elucidate the pattern of spatial development of land space in mountainous areas for sustainable production, living, and ecology, and its intensity and principle of regulation; to assess the vulnerability and regional disaster risk of the imbalance between the role of water and soil in the mountainous areas under changing environment. In addition, we will assess the vulnerability and regional disaster risk of mountainous areas under the changing environment, and explain the coordinated development mechanism of human-land system in mountainous areas of China.
3. Tropical Cyclone Refined Measuring and Reporting Theory and Technology and Disaster Risk Assessment Research
Carry out field observation experiments on the refined structure of landfalling tropical cyclones, study the theory and method of analyzing multi-source data on the refined structure of landfalling tropical cyclones, explore the influence of the environmental field on the development and evolution of mesoscale systems within the landfalling tropical cyclones, and study key techniques of high-resolution numerical forecasting for the distribution of wind and rain in the landfalling tropical cyclones. It will study the key technology of high-resolution numerical forecasting for the distribution of wind and rain in landfalling tropical cyclones, and carry out research on the pre-assessment of the impact of landfalling tropical cyclones on disasters, impact assessment and risk management.
4. Impact of human activities on the Gulf ecological environment
Research on the evolution of the Gulf ecological environment under the influence of high-intensity human activities and the mechanism, the impact of the structure of the Gulf ecosystem and the service function, to explore the scientific basis for the restoration of the Gulf ecological environment and the feasibility of the implementation of the ecological compensation mechanism, for the ecosystem level of the comprehensive management of the Bay to provide a scientific basis.
5. Formation Mechanism and Potential Evaluation of Sandstone Uranium Ore in Northern China
We will determine the regional tectonic and dynamical background of the uranium-forming basins of sandstone uranium ore in northern China; make full use of the data from deep drilling holes in various industries to study the tectonic and sedimentary phases of different types of uranium-forming basins, and the paleo-sedimentary and paleo-climatic environments in which the ore-conferring sands were formed; study the uranium-rich zones in the basins, and compare the differences between ore-containing and non-ore-containing geologic bodies. We will study the uranium-rich areas in the basin, compare the differences between ore-bearing and non-ore-bearing geologic bodies, and recover the formation and evolution process of ore-bearing fluid source, transportation and storage; we will also establish the mineralization model and mineral search model for sandstone-type uranium mines, predict the prospecting and exploration areas and new mine sites, and evaluate the resource potentials of sandstone-type uranium mines in northern China.
6. Regional Characterization, Health Risks and Control of New Persistent Organic Pollutants (POPs) (Category C)
To recognize the transport and evolution of new POPs through the study of long-distance transport and fate of POPs at the regional scale, to identify and recognize the pollutants that have a potential impact on our country's environment and the global environment, and to promote the over-the-horizon study of China's international convention on POPs; Explore the molecular toxicological effects and health impact mechanisms of new POPs, and scientifically assess the exposure level and risk of POPs in China; study the generation and release mechanisms of POPs in major industrial production processes, and develop and propose prevention and control countermeasures and technologies.
7. Research on theories and methods of extended-period weather forecasting (Category C)
Develop statistical models applicable to extended-period weather forecasting in China, establish an advanced extended-period dynamical statistical forecasting system, analyze the physical processes that affect the intra-seasonal oscillation of precipitation in China, study the multi-scale interactions between El Ni?o and the Southern Oscillation (ENSO), the intra-seasonal oscillations, and the weather-scale motion, and analyze the The key pre-signals and predictability of convective activities triggering the tropical Madden-Julian Oscillation (MJO) are analyzed, and the impacts of the tropical-mid-high latitude interaction process and the sea-air and land-air interactions on the intra-seasonal oscillations are studied.
8. Impacts of Offshore Environmental Changes on Marine Organisms and Their Resource Effects (Category C)
To study the characteristics of the changes in the early life history habitats of China's important fishery resources under the pressure of offshore environmental changes, the impacts and mechanisms of the replenishment process, and the adaptive responses of fishery populations to these changes, and to provide scientific basis for the protection and restoration of the critical early life history habitats of fishery populations.
Health Sciences
1. Pathophysiological Mechanisms and Intervention of Respiratory Tract Injury Caused by Environmental Factors
We will study the pathophysiological mechanisms of respiratory tract injury caused by environmental factors, such as atmospheric fine particles (PM2.5), and systematically analyze the molecular mechanisms through the integrated analysis of cellular and animal models, patient phenotypes, and genome changes, so that the molecular mechanisms can be selected as candidate drug targets for important modulation of the respiratory tract. We will systematically analyze the molecular mechanism of respiratory injury through the integrated analysis of cellular models, animal models, patient phenotypes and genomic changes, and select important regulatory molecules as candidate drug targets to provide the basis for new intervention strategies.
2. Formation and elimination of addiction memory of psychoactive substances
To conduct research on neurons and neural circuits related to addiction memory of psychoactive substances, to reveal the molecular basis and signaling pathways of addiction memory formation, retention, extraction and reinforcement, and to study new drug targets and precursor compounds targeting addiction memory, to explore the strategies and means of selective elimination of addiction memory, and to increase the effective rate of intervention on drug relapse. The research will explore the strategies and means to selectively eliminate addiction memory, and improve the effective rate of intervention in relapse.
3. Molecular nutritional mechanism of metabolic syndrome
To study the relationship between nutrition, metabolic homeostasis imbalance and the development of metabolic syndrome, to reveal the mechanism of metabolic homeostasis imbalance promoted by changes in specific nutrition, genes and metabolic pathways, to elucidate the roles of nutritional sensing and cellular stress regulation network in metabolic homeostasis abnormality, and to put forward the early prevention and treatment measures of metabolic syndrome.
4. Basic research on the pathogenesis and diagnosis and treatment of age-related bone diseases (Category C)
Combining clinical and epidemiological work, we will study the pathogenesis of age-related bone diseases such as osteoporosis and degenerative osteoarthropathies, and elucidate the molecular mechanisms of bone development, aging, and homeostasis, in order to lay the theoretical foundation for a new strategy for the prevention and treatment of age-related bone diseases.
5. Research on the role of inflammation-cancer biosignals in tumor development and tumor therapy
The research focuses on the study of inflammation-cancer interaction signals, elucidating the impact of tumor cell death on the cancer inhibition or promotion of natural immune cells, and exploring the methods and mechanisms of remodeling of the anti-cancer function of immune-inflammatory cells; and investigating the relationship between inflammatory response and drug sensitivity and resistance, in order to provide new ideas for tumor therapy. The study of the relationship between inflammatory response and drug sensitivity and resistance will provide new ideas for tumor treatment.
6. Research on early molecular events in precancerous lesions and invasion of malignant tumors
Taking one or two malignant tumors as the target, research on early molecular events in precancerous lesions and invasion of tumors will be carried out to discover new markers for tumor diagnosis and treatment, and to put forward effective means of curbing precancerous lesions and invasive tumors, so as to improve the level of tumor diagnosis and treatment.
7. Basic research on the regulation and pathogenesis of immune cell subpopulations in chronic inflammatory diseases and targeted therapies (Category C)
Combined with the foundation of the production and maintenance of immune cell subpopulations, the research will study the regulation of cell subpopulations (e.g., T-cells, B-cells, or dendritic cell subpopulations) in inflammatory and immune diseases as well as their pathogenesis, and will put forward new ideas and strategies for targeted therapies.
8. Organ transplantation immune tolerance research (Category C)
Taking the transplantation of one important organ as the target, research on the cellular and molecular mechanism of immune tolerance, search for immune tolerance markers, explore new solutions for the induction of immune tolerance in organ transplantation, reduce chronic immune rejection of the implanted organ, opportunistic infections or tumorigenesis of the patients, and improve the long-term survival rate.
Topics on Chinese medicine theories
1. Clinical research on theories related to qi and blood
Based on the organs and signs, we will study the theoretical basis of qi as the commander of blood and blood as the mother of qi, elucidate the formation process and mechanism of qi deficiency and blood stasis, qi stagnation and blood stasis and qi failure to take in blood, and reveal the efficacy mechanism of qi and blood treatment for clinically effective illnesses.
2. Research on the mechanism of moxibustion based on clinical evidence
Using the evidence of the clinical efficacy of moxibustion as a carrier, we will systematically reveal the characteristics and biological basis of moxibustion, elucidate the key factors affecting moxibustion efficacy, and comparatively study the similarities and differences between the effects of moxibustion and needling.
Utilizing modern imaging technology and other means to explore new methods of meridian research, laying the foundation for the study of the scientific connotation of meridians in Chinese medicine.
Basic research on important infectious diseases
1. Evolutionary mechanisms of key biological characteristics of important pathogenic bacteria
To take Enterobacteriaceae, Mycobacteriaceae, and Fusobacteriaceae as the object of research, and to study the evolutionary mechanisms of their key biological characteristics, such as pathogenicity, natural survival and dissemination, and resistance to drugs, in order to lay the foundation for the prevention and treatment of diseases caused by these pathogenic bacteria. The basis for the prevention and treatment of diseases caused by these pathogenic bacteria is laid.
2. Immune escape and immunopathology of chronic viral hepatitis C
We study the virological characteristics of infection and replication of the main endemic strains of hepatitis C virus (HCV) in China and the regulation of host cells, and describe the similarities and differences in the response to antiviral therapy of different endemic strains of HCV; we also analyze the characteristics of the immune response to self-limited and persistent infections, and describe the signaling mechanisms of recognition and response of natural immunity, as well as the establishment of the antiviral response to HCV. We will analyze the characteristics of immune responses to self-limited and persistent infections, explain the signaling mechanism of natural immune recognition and response, the immune escape pattern of HCV in the establishment of persistent infections, as well as the major extrahepatic disease mechanisms such as the pathological progression of hepatitis C and the disorders of glucose and lipid metabolism, so as to lay a theoretical foundation for the development of antiviral drugs and vaccines against the major prevalent HCV strains.
Materials Science
1. Key Issues of Inorganic Dielectric Materials for High Energy Density
To address the demand for inorganic dielectric materials and capacitors for energy storage devices used in major national engineering projects, we are studying the effects of dielectric material components, micro and nanostructures, and heterogeneous interfaces on electrode polarization, charge storage and transfer, and researching the dielectric materials of capacitors with ultra-high energy density. In the high field of dielectric properties of capacitors under the change and regulation of the principle of exploring new mechanisms to improve the energy density and capacity of the dielectric, research on large-capacity ultra-high energy storage density capacitor preparation science, integration technology and service characteristics.
2. High-performance rubber materials research
Around the high performance of rubber materials for automobile tires, focusing on small cars, research on its molecular design and controlled synthesis, as well as its chain structure, aggregation structure, rubber compound system of multi-level multi-scale structure on the material performance of the law, to improve tire abrasion resistance, reduce abrasion and particulate emissions, and improve the rolling resistance, wet slip and other service performance. The tire will be able to improve rolling resistance, anti-slip and other service performance.
3. High-speed and heavy-duty rail transit wheel and rail system metal materials research
Research high-speed and heavy-duty rail transit in the operating environment of the wheel and rail system rim metal materials constraints to brittle, high strain, fatigue damage, dynamic recession and other security deterioration and impact on the life cycle of the scientific issues, the development of a new generation of wheel and rail material prototypes, the establishment of the wheel and rail metal material service evaluation system.
4. Atomic Scale Observation and Characterization of Microstructure and Properties of New Functional Materials (Class C)
Developing advanced characterization methods such as sub-Ermian resolution imaging, pico-precision displacement measurement, and elemental resolution of atoms, to study the crystallographic properties of microstructure of new multiferroic materials in the form of polarized microstructures, domains and domain walls, grain boundaries, and phase boundaries, as well as the characteristics and coupling between them and their properties, including the atomic configurations, electronic structures and magnetic structures. properties, atomic configurations, electronic structures, magnetic structures, etc., and the coupling between them and their evolution under the action of external fields, to elucidate the relationship between them and the material properties.
5. High-efficiency, low-cost organic polymer light-emitting materials research
For large-size, flexible and low-cost processing of organic display devices, characterized by solution processing process, the study of solution processing process-oriented blue, green, red and other high-efficiency organic polymer light-emitting materials and related materials to match the molecular design of the material, energy level regulation and control of the preparation of a new generation of low-cost organic light-emitting materials to explore new theories and new structures, proposed a new generation of low-cost organic light-emitting material The new theory and structure of the new generation of low-cost organic light-emitting materials, proposed low-cost fully printed displays and high-performance flexible display production of new processes and new ways.
6. Research on the performance of concrete materials and structures under severe environmental conditions
Research on the degradation mechanism of concrete materials and structures under the severe environment in the ocean and the west, and the microstructure of long-life concrete materials and optimization of their performance, to provide a scientific basis for the design of major infrastructure projects for safe service and durability.
7. Structure and Performance Evolution of Lightweight Thermal Protection Materials (Class C)
In response to the development needs of the new aircraft in the future, research on the design and realization of reusable lightweight thermal protection materials, reveal the relationship between the microstructure and performance of the materials, elucidate the evolutionary law of the materials in the process of service, and establish a performance evaluation system for the reusability of lightweight thermal protection materials.
8. Application-oriented high-performance water treatment membrane design and preparation (Class C)
Water desalination and other water treatment membrane high performance and batch preparation uniformity as the research goal, the study of the resin molecular structure and aggregation structure of the formation of nanoscale holes and the regulatory mechanism, the formation of defects in the membrane and its control principle, the membrane of the uniformity of the batch preparation and the stability of the impact of the law of the service, to lay a scientific foundation for the comprehensive enhancement of the level of China's water treatment membrane. To enhance the level of water treatment membranes in China to lay a scientific foundation.
Manufacturing and engineering science field