Pharmaceutical plant to purify the workshop?

Pharmaceutical plant room air purification workshop system to provide air quality will directly affect the level of particulate and microbial contamination in the production of pharmaceutical products in this environment, and thus directly affect the quality of pharmaceutical production. Air purification system is a dynamic system, need to pay attention to the operational status of the system. There are two concepts of air purification system: one is positive pressure control to prevent the influence of outside air on the environment; the other is negative pressure control to prevent the spread of particulate contamination generated during the production process. Air conditioning design, installation and operation should meet different purposes, so the system needs to be rigorously tested, controlled and verified.

The main purpose of the air purification system in a pharmaceutical plant is to prevent microbial contamination of products and clean areas, to prevent the proliferation and contamination of viruses, pathogenic bacteria and bacilli used in pharmaceutical production, to prevent the proliferation and contamination of, for example, penicillin or other highly reactive pharmaceutical products, and to prevent proliferation of solid dust contamination. Therefore, in the validation of the air purification workshop system should focus on the following points: firstly, the flow of air must be from the critical area or cleaner area to the surrounding area or low-level area; secondly, in order to ensure the cleanliness of the regional air and air flow, air intake and exhaust air must be balanced to ensure that the number of air changes, airflow model, differential pressure; and then secondly, each room of the operation area should be the following Indicators for control: the location and number of air supply, the location and number of exhaust air, the number of air changes, the proportion of exhaust air, the airflow model of the product exposed area, the air velocity of the product exposed point, etc.; Finally, the cleanliness determination should include the determination of suspended particles and microorganisms. The pharmaceutical industry has quite strict requirements for air purification systems, including air intake, air treatment, air supply, air exhaust, etc. Therefore, air purification systems must be periodically tested for their quality characteristics.