Dendritic cells, also known as DC cells, are a type of immune cells that do not directly attack cancer cells, but convey the specificity of cancer cells to T lymphocytes (specificity: normal cells If not, it allows aggressive immune cells to recognize the antigens of cancer cells) and play the role of issuing instructions, just like a "command tower". When specifically implementing treatment, cancer antigens must be added to dendritic cells in vitro (induction) and then reinfused back into the patient's body. Dendritic cells send instructions to T cells, and the T cells recognize cancer cells and attack them based on the antigen instructions they received.
αβ T cell therapy is a treatment method that comprehensively activates and proliferates T cells, one of the cells with the strongest attack ability against cancer, and then infuses them back into the patient's body. Because about 95% of T lymphocytes are αβ T cells, this treatment is called αβ T cell therapy. αβ T cell therapy does not have specificity for cancer antigens. When the patient's cancer antigen cannot be determined, or the cancer cells themselves hide the cancer antigen in the cell membrane, αβ T cell therapy can play a role. It is widely used from early to late stage cancers. Medical research shows that the immune function of most cancer patients is suppressed by tumors, and αβ T cell therapy can help relieve the patient’s immune suppression state. If combined with radiotherapy and chemotherapy at the same time, you can expect to increase the efficacy.
γδT cells can quickly sense and attack cells infected by bacteria and viruses, or cells that have undergone initial canceration. But at the same time, the content of γδ T cells in T lymphocytes is very small, only a few percent. It is generally difficult to culture them in vitro for treatment, and only a few medical institutions in Japan have the ability to culture them. If you are currently using antibody drugs for treatment, or are using zoledronic acid for the treatment of myeloma, bone metastasis, etc., you can expect better therapeutic effects if combined with γδ T cell therapy.
NK cells (natural killer cells) account for about 10 to 20% of the peripheral blood. They are cells with powerful cell killing capabilities. Usually NK cells "patrol" in the human body and launch attacks when they find cancer cells or abnormal cells infected by viruses, which is equivalent to the early attack force in the battle. NK cell therapy is a therapy that collects NK cells from the patient's body, activates and proliferates them in vitro, and then infuses them back into the patient's body.
Divided into 4 types of treatments
The effects vary from person to person