Relative Vapor Density (air=1): 2.20
Saturated Vapor Pressure (kPa): 53.32 (-3.9°C)
Heat of Combustion (kJ/mol): 1349.3
Critical Temperature (°C): 187.2
Critical Pressure ( MPa): 5.23
Logarithmic value of octanol/water partition coefficient: 1.54
Flash point (℃): -43 (O.C)
Ignition temperature (℃): 510
Explosive upper limit % (V/V): 14.8
Lower explosive limit % (V/V): 3.6
Solubility: slightly soluble in water, miscible in most organic solutions. Solubility: slightly soluble in water, miscible in most organic solvents.
Main uses
To be used as tetraethyl lead, ethyl cellulose and ethyl carbazole dyes and other raw materials. It is also used as a smoke agent, refrigerant, local anesthetic, insecticide, ethylating agent, olefin polymerization solvent, gasoline shock absorber, etc. It is also used as a catalyst for polypropylene. It is also used as catalyst for polypropylene and solvent for phosphorus, sulfur, oil, resin and wax. Synthesis of pesticides, dyes, pharmaceuticals and their intermediates.
Health Hazards
Stimulating and anesthetic effects. High concentrations damage the heart, liver and kidneys. Inhalation of 2% to 4% concentration can cause motor disorders, mild hyperalgesia, and quickly appear the loss of consciousness, but its stimulating effect is very mild; high concentrations of exposure to cause anesthesia, central inhibition, there can be circulatory and respiratory depression. Skin contact can be caused by rapid local cooling, resulting in frostbite.
Danger of ignition and explosion: This product is flammable and irritating.
II. Vinyl chloride
Summary: vinyl chloride is an important monomer used in polymer chemistry, can be produced by ethylene or acetylene. It is a colorless, easily liquefied gas with a boiling point of -13.9℃, a critical temperature of 142℃, and a critical pressure of 5.22MPa. Vinyl chloride is a toxic substance, and liver cancer is related to long-term inhalation and exposure to vinyl chloride. It forms explosive mixture with air, the explosion limit is 4%～22% (volume), it is more likely to explode under pressure, it is necessary to pay attention to the tightness of the container and nitrogen sealing when storing and transporting, and a small amount of polymerization inhibitor should be added.
Basic Information
Molecular Formula: C2H3Cl
Structural Formula: CHCl=CH2
Molecular Weight: 62.50
Hazardous Composition Contained CAS No.
Vinyl Chloride ≥99.99% 75-01-4
Main Ingredients: Contained: Purity ≥99.99 %.
Appearance and properties: colorless gas with ether-like odor.
pH: meaningless
Melting point (℃): -159.8
Boiling point (℃): -13.4
Relative density (water = 1): 0.91
Relative vapor density (air = 1): 2.15
Saturated vapor pressure (kPa): 346.53 (25 ℃)
Heat of combustion (kJ). Heat of combustion (kJ/mol): not available
Critical temperature (℃): 142
Critical pressure (MPa): 5.60
Logarithmic value of the partition coefficient of octanol/water: 1.38
Flash point (℃): meaningless
Ignition temperature (℃): 415
Upper explosive limit (V/V): 31.0
Upper explosive limit (V/V): 415
Upper explosive limit (V/V): 31.0
Upper explosive limit (UV): 31.0
UV : 31.0
Lower Explosive Limit %(V/V) : 3.6
Physical and Chemical Properties
Main Ingredients: Content: Purity ≥99.99%.
Appearance and properties: colorless gas with ether-like odor.
Melting point (℃): -160.0.
Boiling point (℃): -13.9.
Relative density (water=1): 0.91.
Relative vapor density (air=1): 2.15.
Vapor pressure (kPa): 346.53 (25℃).
Heat of combustion (kJ/mol):
Flash point (℃):
Stability and reactivity:
Prohibited compounds: strong oxidizing agents. Avoid heat.
Hazardous Characteristics: Flammable, can form explosive mixtures when mixed with air. There is a danger of combustion and explosion when it meets heat source and open flame. Burning or no inhibitor can occur when the violent polymerization. Its vapor is heavier than air, can be diffused in the lower place to a considerable distance, will catch fire when ignition source back to combustion.
Solubility: slightly soluble in water, soluble in most organic solvents such as ethanol, ether, acetone.
Use
Mainly used in the production of polyvinyl chloride, and can be used with vinyl acetate, acrylonitrile, acrylic esters, vinylidene chloride (1,1-dichloro vinyl chloride) and other **** polymerization, the production of a variety of properties of the resin. In addition, it can also be used to synthesize 1,1,2-trichloroethane and 1,1-dichloroethene.
Hazards of vinyl chloride
Acute toxicity: short-term inhalation of a large amount of vinyl chloride, due to its anesthetic effect of central nervous system inhibition, can lead to acute poisoning.
Subacute and chronic toxicity: . It is a carcinogen and can cause hepatic hemangiosarcoma.
Metabolism: In production conditions, long-term inhalation of high concentrations of vinyl chloride air personnel, in their blood accumulation of considerable vinyl chloride and the formation of metabolites, thus creating a serious harm to the human body, this accumulation and metabolism in the blood, a long time, the consequences of serious.
Irritant: irritant, short-term exposure to low concentrations, can irritate the eyes and skin, and its liquid contact due to rapid evaporation can cause frostbite.
Carcinogenicity: IARC: Human carcinogen.
Teratogenicity: Rat inhalation TCL0: 500 ppm (7 h), 6-15 d of pregnancy, causing embryotoxicity. Mice inhaled TCL0: 500 ppm (7 h), 6-15 d of gestation, causing embryotoxicity and abnormal musculoskeletal development.
Mutagenicity: Microbial mutagenicity: Salmonella typhimurium 2000 ppm (48 h). Cytogenetic analysis: human Hela cells 10 mmol/L.
Hazard classification (GB 5044-85): Class I (extremely hazardous)
Environmental hazards: Vinyl chloride can participate in photochemical smog reaction in the environment.
Migration transformation and degradation: the process of industrial enterprises to make, produce and process polyvinyl chloride as well as the production of various polymers based on polyvinyl chloride is the main source of vinyl chloride precipitation and enter into the environment, due to the fact that the various polymerization materials based on polyvinyl chloride contain vinyl chloride monomer which does not take part in the polymerization reaction, and it can be escaped and enter into the environment during the exposure process. As a hydrocarbon, vinyl chloride can participate in photochemical smog reactions in the environment; vinyl chloride is moderately reactive compared to similar hydrocarbon molecules. Atmospheric oxidation products of vinyl chloride include formaldehyde, formic acid, and hydrogen chloride.
Other harmful effects: vinyl chloride can participate in the photochemical smog reaction in the environment; due to its high volatility, it is easily photolysed in the atmosphere, and it can also be biodegraded and chemically degraded
III. Polyvinyl Chloride
Summary
Polyvinyl Chloride abbreviated as PVC, polymerized from vinyl chloride under the action of the initiator of the thermoplastic resin, is a homopolymer of vinyl chloride. Polyvinyl chloride is one of the world's largest production of plastic products, cheap, widely used, polyvinyl chloride resin is white or light yellow powder. According to different uses can be added to different additives, polyvinyl chloride plastic can show different physical properties and mechanical properties. Adding the appropriate amount of plasticizer in the polyvinyl chloride resin, can be made into a variety of hard, soft and transparent products. Polyvinyl chloride can be made into various profiles and products through plastic processing. ① General soft products. The use of injection molding machine with a variety of molds, can be made of plastic sandals, soles, slippers, etc.. Film. The use of three-roller or four-roller calender made of transparent or colored film of a specified thickness. Film is very versatile, can be cut, heat-laminated into bags, raincoats, tablecloths, curtains, inflatable toys and so on. ③ Coated products. Such as artificial leather. Artificial leather can be used to make leather boxes, leather bags, book covers, sofas and car seat cushions. Foam products. Such as foam, can be used as foam slippers, sandals, insoles, cushions, and shockproof cushioning packaging materials. ⑤ Transparent sheet. The use of thermoforming can be made into thin-walled transparent containers or used for vacuum blister packaging, is an excellent packaging material and decorative materials. (6) Paste products. (7) Rigid tubes and plates. ⑨ hollow containers
Physical and chemical properties
Stable; not easily corroded by acids and alkalis; more resistant to heat
PVC has the advantages of flame retardant (flame retardant value of more than 40), high resistance to chemicals (resistant to concentrated hydrochloric acid, concentration of 90% of the sulfuric acid, concentration of 60% of nitric acid and concentration of 20% of the sodium hydroxide), mechanical strength and good electrical insulation. However, its heat resistance is poor, the softening point is 80 ℃, at 130 ℃ began to decompose and discoloration, and precipitation of HCI. has a stable physicochemical properties, insoluble in water, alcohol, gasoline, gas, water vapor leakage is low; at room temperature can be resistant to any concentration of hydrochloric acid, sulfuric acid of less than 90%, 50-60% of the nitric acid and caustic soda of less than 20% of the solution, a certain degree of chemical corrosion resistance; quite resistant to salts, good mechanical strength and electrical insulation. Chemical corrosion; quite stable to salts, but can be dissolved in ether, ketone, chlorinated aliphatic hydrocarbons and aromatic hydrocarbons and other organic solvents. In addition, POVC light, thermal stability is poor, above 100 ℃ or after a long period of sun exposure, it will decompose to produce hydrogen chloride, and further autocatalytic decomposition, discoloration, physical and mechanical properties decline rapidly, so in practical applications must be added to stabilizers in order to improve the stability of heat and light.
Polyvinyl chloride-application range
It is because of its fire-resistant and heat-resistant role, polyvinyl chloride is widely used in wire sheathing and fiber optic sheathing. It is also often used to make gloves, and as a wrapping paper for certain foods.
PVC can be made from ethylene, chlorine and a catalyst.
Recycling and Recycling
Resource Recovery and Recycling: International Plastics Recycling Code: PVC is 3 (3 in the center of the three recycling arrows)
PVC - Hazards
PVC is also a frequently used plastic, which is made up of a polyvinyl chloride resin, plasticizers, and antioxidants, which is non-toxic in itself. However, the added plasticizer, antioxidant and other major auxiliary materials have toxicity, daily use of polyvinyl chloride plastic in the plasticizer, the main use of dibutyl terephthalate, dioctyl phthalate, etc., these chemicals have toxicity, polyvinyl chloride antioxidant lead salts of stearic acid is also toxic. Polyvinyl chloride (PVC) products containing lead salt antioxidants will precipitate lead when in contact with ethanol, ether and other solvents. Lead-containing salts of polyvinyl chloride used as food packaging and doughnuts, fried cakes, fried fish, cooked meat products, cakes and snack foods meet, it will make the lead molecules diffuse into the grease, so you can not use polyvinyl chloride plastic bags containing food, especially can not be loaded with oil-containing food.
In addition, PVC plastic products at higher temperatures, such as about 50 ℃ will slowly decompose hydrogen chloride gas, this gas is harmful to the human body, so PVC products should not be used as food packaging. Bakelite (phenol-formaldehyde plastic) contains free phenol and formaldehyde, which is toxic to the human body, and is not suitable for storing food and food packaging. Bakelite (urea-formaldehyde plastic), although odorless and tasteless, but in 100 ℃ boiling water or used as a vinegar food, there will be free formaldehyde precipitation, harmful to human health, so it is also not suitable for food utensils or food packaging. Renewal of waste plastics (some may add a little new material), because of its complex composition, it is difficult to ensure that there is no toxicity, so generally can not be used as food containers and packaging. [1]
Trichloromethane
Trichloromethane is the scientific name of chloroform, also known as "Glofen", "trichloromethane" and "carbon trichloride". Chloroform for the English Chloroform half-meaning half-sound translation; Glofen for sound translation. At room temperature is colorless transparent heavy liquid, very volatile, taste sweet and have a special aromatic odor.
Properties
Melting and boiling point (℃) Melting point: -63.7 ,Boiling point: 61.2
Density
Relative density (water=1): 1.48g/cm3; (liquid)
Relative vapor density (air=1): 4.12
Solubility
Solubility in water: 0.8 g Solubility in water: 0.8 g /100 ml, 20 °C
Others
Saturated vapor pressure (kPa): 13.33 (10.4 °C)
Critical temperature (°C): 263.4
Critical pressure (MPa): 5.47
Logarithmic value of the partition coefficient of octanol/water: 1.97
Triclocarbomethane is also known as chloroform. It is also known as chloroform. Three hydrogen atoms in the methane molecule are replaced by chlorine and generated compounds, molecular formula CHCl3. colorless volatile liquid; slightly sweet odor; melting point -63.5 ℃, boiling point 61.7 ℃, relative density 1.4832 (20/4 ℃); slightly soluble in water, soluble in ether, ethanol, benzene, etc.; difficult to burn.
Trichloromethane can be oxidized to hydrogen chloride and highly toxic phosgene by oxygen in the air under light:
Main Uses
Chloroform is a raw material for organic synthesis and is mainly used to produce Freon (F-21, F-22, F-23). In addition, it is also used as a solvent for organic synthesis and anesthetics; fat, rubber, resin, oil, wax, phosphorus, iodine and adhesive acrylic; extractant for penicillin, essential oils, alkaloids and so on; determination of inorganic phosphorus in serum; cleaning agent; preservative for liver function test and so on. It is a necessary cleaning agent for cell phone repairers.
Chloroform mixed with carbon tetrachloride can be made into a non-freezing fireproof liquid. It is also used as a launching agent for smoke agents, a fumigant for grains, and a standard liquid for calibrating temperature. Industrial products are usually added with a small amount of ethanol, so that the resulting phosgene acts with ethanol to produce non-toxic diethyl carbonate
Hazards
Trichloromethane mainly acts on the central nervous system, has anesthetic effects, and is damaging to the heart, liver and kidney.
Environmental hazards: Hazardous to the environment, can cause pollution of water bodies.
Danger of ignition and explosion: This product is non-flammable, toxic, suspected carcinogen, irritating.
Hazardous Characteristics: When in contact with open fire or hot objects, it can produce highly toxic phosgene.
Difficult to burn. Trichloromethane can be oxidized to hydrogen chloride and highly toxic phosgene by oxygen in the air under light
IV. HCFC
is a class of organic compounds, mainly chlorine atoms to replace the hydrogen in methane, and then pass into the hydrofluoric acid.
HCFCs are widely found in a variety of older refrigerants as a heat exchange medium. HCFCs exothermize when compressed and absorb large amounts of heat when the pressure is reduced.
HCFCs can produce chlorine atoms under ultraviolet light as a catalyst for ozone decomposition. Therefore, it is very harmful to the ozone layer. Some studies have blamed the abuse of HCFCs as a major cause of the hole in the ozone layer. Therefore, our government has completely banned the use of HCFCs in domestic refrigeration appliances.
Dichlorodifluoromethane is a classical HCFC with the chemical formula CF2Cl2, which is obtained by substituting dichloromethane with hydrogen fluoride gas.
HCFCs are chemically stable, low-toxicity, and some have a slight flavor
V. Tetrafluoroethylene
Tetrafluoroethylene is mainly produced by chloroform, can also be produced by tetrafluorodichloroethane catalyzed dechlorination in the presence of aluminum trifluoride. It is a colorless and odorless gas at room temperature, with a boiling point of -76.3℃; it can be liquefied under pressure, with a critical temperature of 33.3℃ and a critical pressure of 3.92MPa. Unlike many other fluorinated hydrocarbons, tetrafluoroethylene is toxic. Mainly used in the production of a wide range of temperatures, high chemical stability of polytetrafluoroethylene; can also be used with ethylene or hexafluoropropylene **** poly preparation of fluorine-containing insulating materials, or with vinylidene fluoride **** poly production of fluorine-containing fibers.
Properties: colorless and odorless gas. Melting point -142.5℃, boiling point -76.3℃, insoluble in water. Heavier than air. Relative density 1.519, critical temperature 33.3℃, critical pressure 3.92MPa, ignition point 620℃. Soluble in acetone, ethanol. Self-ignition limit is 11%-60% (volume), ignition temperature is only 180℃. In the presence of oxygen, it is easy to form unstable and explosive peroxide. Preparation method: difluoromethylene chloride by gasification, preheating, through the cracking furnace, thermal cracking production of cracked gas containing tetrafluoroethylene monomer, by water washing, alkali washing, compression, freezing dehydration, drying, fractionation and other processes, and finally distillation of finished products.
Use: Manufacture of PTFE and other fluoroplastics, fluorine rubber and perfluoropropylene monomer. It can be used as raw material for manufacturing new thermoplastics, engineering plastics, oil and low temperature resistant rubber, new fire extinguishing agent and fog suppressant
Hazard Overview
Hazard Category: Disproportionation reaction triggered by local overheating
Health Hazard: Acute Poisoning: Coughing, tightness in the chest, dizziness, weakness, nausea in the less severe cases.
Environmental hazards: the atmosphere can cause pollution.
Explosion Hazard: This product is flammable.
VI. Perchloroethylene
Brief description: also known as perchloroethylene. It is a compound produced by substituting chlorine for all hydrogen atoms in ethylene, molecular formula Cl2C noise CCl2, colorless liquid, melting point -19℃, boiling point 121℃, relative density 1.6227(20/4℃), insoluble in water, soluble in ethanol, ether and benzene, etc., smells like ether, not combustible.
Properties: tetrachloroethylene is more stable, not easy to occur addition reaction. When it acts with sodium ethanol, the chlorine atom can be replaced by ethoxy, generating dichloro vinyl ketone ethyl acetal, and then add with ethanol, hydrolyzed to get ethyl dichloroacetate:
Role: tetrachloroethylene is mainly used as organic solvents, dry cleaning agents and metal degreasing agents; it has been used to expel hookworms and ginger bugs in the body; it has anesthesia in high concentration, and it can degrease and cause dermatitis on the skin.
Hazards: A new study shows that women who are exposed to too much perchloroethylene during pregnancy increase the risk of newborns developing cleft lip and palate and neurological birth defects.
VII. Heptafluoropropane
-Heptafluoropropane is a colorless, odorless, gaseous fluorinated hydrocarbon that is a common material for fire extinguishing agents. Heptafluoropropane is a common material for fire extinguishing agent. The fire extinguishing agent counting with Heptafluoropropane as raw material are: HFC-227 HFC-227ea MH-227 (Shanghai Waysmos) FE-227, and FM-200
Heptafluoropropane-Chemical Properties
Heptafluoropropane has the chemical formula of CF3-CHF-CF3, or C3HF7, and the melting point is ?131 °C. The boiling point is ?166 °C. The chemical formula of Heptafluoropropane is CF3-CHF-CF3, or C3HF7, The boiling point is ?16.4 °C. It is slightly soluble in water (260 mg/L).
Parameters of Heptafluoropropane:
Ozone Depletion Potential (ODP) = 0
Greenhouse Potential (GWP) = 0.6
Atmospheric Lifespan (ALT) = 31 years
Non-toxic Reaction Concentration (NTRC) of the extinguishing agent NOAEL = 9.0%
Toxic Reaction Concentration (TRC) of the extinguishing agent LOAEL = 10.5%
Toxic reaction concentration of the extinguishing agent LOAEL = 10.5%
Extinguishing design basic concentration C = 8%
Lower than NOAEL and LOAEL, relatively safe.
Heptafluoropropane-Application of Heptafluoropropane
Since Heptafluoropropane does not contain chlorine or bromine, and does not destroy the ozone layer of the atmosphere, it has been adopted as the raw material for fire extinguishing agent to replace Halon 1301 and Halon 1211, which are harmful to the environment. Heptafluoropropane has an atmospheric life cycle of about 31 to 42 years and is suitable for use as an extinguishing agent in data centers or server storage centers because it does not leave residues or oil stains after it is released, and it can also be vented through normal exhaust channels. Usually, these places will install a tank containing compressed Heptafluoropropane on the top of the floor. When a fire occurs, the Heptafluoropropane will be discharged from the tank's air outlet, rapidly removing oxygen from the place where the fire occurs and cooling the place where the fire occurs, so as to achieve the purpose of extinguishing the fire.
While Heptafluoropropane is stable at room temperature, it decomposes at high temperatures and produces Hydrogen Fluoride (HF), which produces a pungent odor. Other combustion products include carbon monoxide and carbon dioxide.
Contact with liquid Heptafluoropropane can cause frostbite.
Heptafluoropropane can also be used as a propellant for launching rockets.
Sevoflurane is used in dosage inhalers for dispensing measurements, such as those used in asthma regimens.
VIII. Carbon tetrachloride
Carbon tetrachloride (carbon tetrachloride, CCl4), chemical formula CCl4. CAS No.: 56-23-5, also known as tetrachloromethane (tetrachloromethane), colorless, volatile, non-flammable liquid. It has the slightly sweet odor of chloroform. And has a pleasant odor. Molecular weight 153.84, density 1.595g/cm3(20/4℃), boiling point 76.8℃, vapor pressure 15.26kPa(25℃), vapor density 5.3g/L. Slightly soluble in water, miscible with ethanol, ether, chloroform and petroleum ether. It can be decomposed into carbon dioxide, hydrogen chloride, phosgene and chlorine gas when it meets fire or incandescent material.
Main Properties
Carbon tetrachloride is a colorless, clear, easy-to-flow liquid, sometimes slightly yellow due to impurities in industry, with an aromatic odor, volatile. Density (20 ℃) 1.595 g / cm3, melting point -22.8 ℃, boiling point 76 ~ 77 ℃. The vapor of carbon tetrachloride is about 5 times heavier than air and will not burn. The vapor of carbon tetrachloride is toxic, its anesthesia is lower than chloroform, but the toxicity is higher. Inhalation of 2 to 4 milliliters can cause death. The solubility of carbon tetrachloride in water is very small, and it is gradually decomposed into hydrochloric acid when it meets moisture and light. It is easily soluble in various organic solvents and can be mixed with alcohol, ether, chloroform, benzene and so on. For fats, oils and a variety of organic compounds for a very good solvent.
When carbon tetrachloride is used as a fire extinguishing agent, it cannot extinguish the fire of active metals, because active metals can react with it
Toxic hazards
CCl4 is a typical liver poison, but the concentration and frequency of exposure can affect its site of action and toxicity. At high concentrations, the central nervous system is involved first, followed by the liver and kidney; while low concentrations and long-term exposure mainly show liver and kidney involvement. Ethanol can promote the absorption of carbon tetrachloride and aggravate the symptoms of poisoning. In addition, carbon tetrachloride can increase the sensitivity of the heart muscle to adrenaline, causing serious arrhythmia. Individual susceptibility to carbon tetrachloride varies greatly, and it has been reported that 3-5 ml of carbon tetrachloride can be poisoned by oral intake, and 29.5 ml of carbon tetrachloride can be fatal. Poisoning can occur at a concentration of 160-2OOmg/m3. However, there are also cases of mild poisoning in 1-2g/m3 concentration after 3Omin exposure. At present, it is believed that carbon tetrachloride is not teratogenic or mutagenic, but it is embryotoxic. According to IARCl972 and 1979 data, carbon tetrachloride long-term effect can cause liver cancer in rodents, is classified as "carcinogenic to humans" a class of chemicals.
Studies have shown that CCl4 reacts with water at high temperatures to produce the toxic substance phosgene
Uses: Carbon tetrachloride is mainly used as a solvent and fire extinguishing agent, but also used in the production of Freon, can be used as an anesthetic in medicine.
9. DDT
DDDT is also known as DDT, two or two or three, the chemical name of the double p-chlorophenyltrichloroethane (Dichlorodiphenyltrichloroethane), the chemical formula (ClC6H4)2CH (CCl3). The Chinese name comes from the English abbreviation DDT, white crystal, insoluble in water, soluble in kerosene, can be made into emulsion, is an effective insecticide. For the first half of the 20th century to prevent agricultural pests and diseases, reduce malaria typhoid fever and other mosquito and fly-borne disease hazards played a small role.
Physical and chemical constants of the substance
Molecular Formula C14H9Cl5 Appearance and properties All isomers of DDT compounds are white crystalline solids or yellowish powder, odorless, almost tasteless
Molecular Weight 354.5 Vapor Pressure 2.53×10-8kPa/20°C Flash Point: 72-77°C
Melting Point 108～109 ℃ Boiling point: 260 ℃ Solubility DDT is extremely difficult to dissolve in water, in the organic solvents are as follows (g/100ml): benzene 106, cyclohexanone 100, chloroform 96, petroleum solvents 4-10, ethanol 1.5
Density 1.55 (25 ℃ ) Stability DDT is chemically stable and does not decompose at room temperature. It is stable to acid, strong alkali and iron containing solution can easily promote its decomposition. When the temperature is higher than the melting point, especially in the presence of a catalyst or light, p,p'-DDT can form DDE by dechlorinating hydrogen
Hazardous Labeling 14 (with drugs), Main Uses: Used as an agricultural pesticide
Health Hazards Routes of Invasion
Inhalation, ingestion, and percutaneous absorption.
Health hazards
Mild poisoning can be headache, dizziness, weakness, sweating, insomnia, nausea, vomiting, and occasional twitching and tremor of hand and finger muscles. Severe poisoning is often accompanied by high fever, excessive sweating, vomiting, diarrhea; nervous system excitement, upper and lower limbs and facial muscles were tonic convulsions, and epileptic convulsions, convulsive seizures, on the person, whether intentional or negligence caused by a large amount of consumption, that can cause poisoning