1. Right-click My Computer → Manage → Device Manager → Check whether the mouse is normal. If it does not work properly, install the driver.
2. Either it is a system problem, reinstall the system.
3. Whether any third-party software has been installed recently may also cause compatibility issues. You can boot in safe mode to see if the mouse works well. If it works, then the fault is caused by recently installed software. Just uninstall this software.
4. Try another USB interface.