Nitric oxide acts as a messenger molecule. When the endothelium wants to send relaxation commands to the muscles to promote blood flow, it produces a number of nitric oxide molecules, which are small enough to cross the cell membrane easily. Smooth muscle cells around blood vessels receive the signal and diastole, causing the blood vessels to dilate. Nitric oxide also works in the cells of the nervous system. The role it plays on peripheral nerve endings. The brain sends a message through the peripheral nerves to deliver the appropriate amount of nitric oxide to the blood vessels in the perineum, causing dilation of the blood vessels and increased blood flow, which enhances erectile function. In some cases, weak erections are due to low production of nitric oxide by the nerve endings. "Viagra amplifies the effectiveness of nitric oxide to enhance erectile function. Nitric oxide molecules produced by the immune system not only fight microorganisms that invade the body, but also prevent cancer cells from multiplying and stop tumor cells from spreading to some extent.
Nitric oxide gas produced in the endothelial cells of blood vessels, because it is fat-soluble, quickly permeates out of the cell membrane to diffuse downward into the smooth muscle cells, thus acting on the smooth muscle cells to relax and dilate the blood vessels, which ultimately leads to a decrease in blood pressure! It will also quickly permeate out of the cell membrane and diffuse upward into the bloodstream and into the platelet cells, reducing platelet activity and inhibiting their agglutination and adhesion to the endothelium of blood vessels, thus preventing the formation of blood clots and the occurrence of atherosclerosis. From the biochemical point of view, nitric oxide is a free radical gas, carrying an unpaired electron, extremely unstable in vivo, this characteristic is exactly the same as other free radicals. This makes it very easy for the two to combine and react. As a result, the number of free radicals in the body is greatly reduced. Since the synthesis of nitric oxide itself requires the participation of nitric oxide synthase (NOS), the activity of NOS is very low under normal conditions, and needs to be activated by nitro drugs or saponin-type active substances. Therefore nitric oxide is best produced in synergy with ginsenosides.