lga nephropathy is a glomerulonephritis characterized by the deposition of lga in the glomerular mesangial area, which is divided into two major categories: primary and secondary. lga nephropathy is a progressive disease, and only a small number of urinalysis abnormalities can be completely remitted. Most patients show chronic progressive progression and eventually develop end-stage renal disease. lga nephropathy is the leading cause of end-stage renal disease in China, and the risk factors for progression are mainly interstitial glomerulosclerosis, interstitial fibrosis, hypertension, massive proteinuria, and renal hypoplasia.
The clinical manifestations of nephropathy are mainly isolated hematuria, repeated episodes of hematochezia, asymptomatic hematuria and proteinuria, which can also be combined with edema, hypertension, and renal hypoplasia, which manifests as nephritic syndrome or nephrotic syndrome. Renal puncture is needed for a definitive diagnosis.