During the production and storage of water for injection, measures should be taken in terms of equipment, pipelines and use management:
1. Early management
The early management of equipment refers to a series of management work before the equipment is put into production and operation. When selecting and purchasing equipment, full communication, investigation, comparison, bidding and selection should be carried out, technical and economic argumentation should be strengthened, and after-sales technical support and operation and maintenance should be fully considered.
2. Use management
The service life management of equipment is divided into initial management, intermediate management and post-management of equipment.
the initial management of equipment generally refers to the management of equipment adjustment, use, maintenance, condition monitoring, fault diagnosis, training and education of operation and maintenance personnel, collection and processing of maintenance technical information from the date of acceptance, and the establishment of equipment fixed assets files, technical files and original records of operation and maintenance.
considerations
the preparation, storage and distribution of water for injection should be able to prevent the breeding and pollution of microorganisms. Materials used for storage tanks and pipelines shall be non-toxic and corrosion-resistant. The design and installation of pipelines should avoid dead corners and blind pipes. Cleaning and sterilization cycles shall be specified for storage tanks and pipelines. The vent of the water storage tank for injection should be equipped with a hydrophobic sterilization filter that does not shed fibers. Water for injection can be stored at 8℃ or above, at 7℃ or below 4℃.
above content reference: Baidu Encyclopedia-Water for Injection