Hemodialyzer assembled by polysulfone hollow fiber membrane, sterilized by ethylene oxide gas or r-ray, this product is non-pyrogenic. It can be used as disposable medical supplies for patients with acute and chronic renal failure due to various causes, and can also be used for rescuing severely traumatized casualties and poisoned patients.
Main technical indexes
1. The technical indexes of various models and specifications of the product are as follows:
Model specifications
REGI 80
REGI 120
REGI 130
REGI 140
Membrane material
Polysulfone class
Dialysis area (m2)
0.8
1.2
1.3
1.4
Membrane inner diameter (μm)
210
Blood compartment volume (ml)
≤70
≤90
≤95
≤100<
Clearance
(ml/min)
Test conditions
QB=200mL/min QD=500mL/min TMP=100mmHg
Urea
155
170
180
187
Creatinine
150
160
170
175
Ultrafiltration coefficient (ml/kPa.h)
25
37
41
45
Maximum use pressure KPa/ mmHg
66.5 / 500
Maximum flow rate (ml/min)
Blood 300 Dialysate 500
Sterilization method and expiration date
EO or r-radiation sterilized, expiration date 2 years
Usage method
1. Connection of the hemodialyzer to the catheter: Take out the hemodialyzer from the complete bag and put the arterial line and the venous line in the bag. Connect the arterial line, venous line and filtrate line to the corresponding tubing of the dialyzer. Attach the dialyzer to the dialyzer fixture with the tubing connected.
2. Fill the device with saline (1000mL or more) to remove residual ethylene oxide gas from the dialyzer and air bubbles from the device and catheter.
3. Heparinize the dialyzer and blood catheter with saline containing heparin (1000 IU/ML).
4. Turn on the dialysate system (bottom in, top out) and circulate for several minutes; turn on the arteries and veins (blood flow from top to bottom) for dialysis.
5. Monitor the dialysis process at all times and add heparin at the appropriate time, both to ensure that no clotting occurs and to avoid excessive heparin that could cause bleeding.
6. At the end of dialysis, access saline (500 mL) to the blood inlet and gradually return the residual blood in the dialyzer to the body.
Precautions for use and storage
1. Strictly check whether the bag is broken or not before using the product, and prohibit use if it is broken. Check whether the sterilization date is within the safe use period.
2. Strictly perform aseptic operation when connecting blood tubes and use it as soon as possible.
3. Care must be taken to ensure that air is not allowed to enter the dialyzer and blood tubing during pre-rinse and rinsing, and that liquid may be discharged from the dialysate port during rinsing.
4. The transmembrane pressure should be kept strictly below 66.5 kPa (500 mmHg), and no unnecessary pressure should be applied to the dialyzer and blood tubing to prevent leakage and dislodgement of the connections.
5. The product is for single use and destroyed after use.
6. WARNING: Please use it in strict accordance with the instructions, and the manufacturer will not be responsible for any consequences caused by violating the operation.
7. Storage requirements: stored in a dry environment at 0-400C. Direct sunlight, intense vibration and intrusion of harmful gases should be avoided.
Complications and treatments
Hemodialysis (HD) treatment has developed over a certain period of time, with dialysis technology becoming more and more mature and equipment becoming more and more perfect, so possible complications during dialysis are relatively rare.
1. Hypotension: Hypotension is the more frequent of the very few complications of dialysis, and is generally characterized by dizziness, blurred vision, sweating, and yawning. The cause of hypotension is generally insufficient effective blood volume, the prevention and treatment method is to prevent excessive ultrafiltration, water and sodium intake should be appropriate, regularly adjust the dry weight.
2. Arrhythmia: maintenance dialysis patients during dialysis, there may be arrhythmia, common causes of hyperkalemia, hypokalemia, cardiomyopathy, coronary artery disease, etc., the treatment should be based on different etiologies and types of arrhythmia were dealt with; dialysis fluid potassium concentration should be selected appropriately, there is a serious anemia in patients with appropriate transfusion or use of EPO, cardiac monitoring during dialysis, and timely delivery of anti-arrhythmic drugs. The patients with severe anemia should be given blood transfusion or EPO.
3. Nausea and vomiting: Nausea and vomiting may occur occasionally during dialysis. Common causes include osmotic imbalance between plasma and dialysate at the beginning of dialysis, hypotension, and certain drugs. In treatment, the cause should be treated, and if the dialysis is too fast, it can be slowed down appropriately. Treatment of hypotension, often check the water quality, prevent hard water configuration dialysis fluid, give antiemetic and sedative symptomatic treatment.