Principles of ethanol-formaldehyde disinfection and sterilization

Principles of ethanol disinfection:

(1) Denaturation of proteins

Ethanol first dehydrates bacterial cells, and the ethanol molecules enter the peptides of the protein molecules. chain link, causing the protein to denature and precipitate; this effect is stronger at a content of 70%.

(2) Destroy the bacterial cell wall

Ethanol has a strong penetrating effect, and 60% to 85% ethanol can easily penetrate into the bacterial body, causing the bacterial cells to be destroyed and dissolved.

(3) Damage to the microbial enzyme system

Ethanol inhibits the bacterial enzyme system, especially dehydrogenase and oxidase, etc., hindering normal metabolism and inhibiting bacterial growth and reproduction.

Principle of formaldehyde sterilization:

Formalin acts on bacterial proteins (including enzymes) to alkylate them, causing protein denaturation and coagulation, causing the death of microorganisms.

p>