What is an argon-helium knife?

Argon-helium knife: Cryo-HITTM cryosurgery system is a minimally invasive medical device for cryoablation of tumors. It is the crystallization of space guidance technology, that is, argon cold isolation technology is applied to medical field. Cryo-HITTM cryosurgery system is a product produced by Galileo Company in Israel. Galileo Israel is a global leader in cryotherapy equipment market, and its R&D headquarters is located in Yorkshire, Israel. Cryo-HITTM cryosurgery system was registered and approved by Israeli Ministry of Health, Health Technology and Structure Administration and Medical Argon-Helium Equipment Department in 1997. 1999 passed the EU CE registration certification; Registered by FDA in 2000, it is the only one in the world approved by FDA to treat liver, lung, breast, uterus, kidney, prostate,

Indications of argon-helium cryotherapy for lung cancer

Surgical exploration (intraoperative combined treatment) of peripheral lung cancer that cannot tolerate surgical resection; central lung cancer involving lobar bronchus, central lung cancer near part of hilum, and more limited metastatic lung cancer.

To edit some research results of argon-helium knife cryoablation for lung cancer.

The one-year survival rate of argon-helium cryotherapy for advanced lung cancer (inoperable) is 865,438+0.67% (the survival rate of early lung cancer is 76%). The effective rate was 69.6%, the complete remission rate was 8.7%, the 1 year survival rate was 69.2%, and the 2-year survival rate was 53.7%. Conclusion: Argon-helium cryotherapy for lung cancer is similar to palliative surgical resection, with less trauma, light reaction, rapid recovery of mental and physical strength after operation and no obvious pain. Argon-helium cryoablation is feasible for locally advanced lung tumors. Argon-helium cryoablation combined with radiotherapy can completely treat locally advanced lung tumors, and the effect is safe and reliable. Compared with chemotherapy alone, argon-helium cryoablation combined with targeted therapy for lung cancer concluded that the complete remission rate and partial remission rate of argon-helium cryoablation combined with chemotherapy were 100%, while the complete remission rate and partial remission rate of chemotherapy alone were 53%. The incidence of liver cancer in China accounts for almost 50% of the world, and one of the key points of cancer prevention and treatment in China is liver cancer. There are 400,000 new cases of liver cancer every year, accounting for 25.0% of the total number of cancer patients in China. First, the treatment of liver cancer Liver cancer is the third largest malignant tumor in China, and the most effective treatment for early liver cancer is surgical resection. However, more than 80% patients lost the opportunity of surgical resection when they were diagnosed. Minimally invasive treatment is mainly used for these patients with advanced liver cancer who can not be surgically removed, and can still achieve exact results. Minimally invasive treatment of liver cancer can be divided into two categories: one is vascular minimally invasive treatment, also known as interventional therapy, including hepatic arterial infusion chemotherapy (TAI), hepatic arterial embolization (TAE) and hepatic arterial embolization chemotherapy (TACE); The other is non-vascular minimally invasive treatment, including percutaneous chemical ablation and percutaneous physical ablation. Percutaneous ethanol injection (PEI) and percutaneous acetic acid injection are commonly used in the former, while the latter includes argon-helium cryoablation, radiofrequency ablation (RFA), microwave coagulation (MCT), laser interstitial hyperthermia and high intensity focused ultrasound. Among them, argon-helium cryoablation, radiofrequency ablation (RFA) and microwave coagulation (MCT) are more and more widely used in clinic. Argon-helium cryosurgery can kill cancer cells by ultra-low temperature (about-140℃), which has the function of hyperthermia. Both radiofrequency ablation and microwave coagulation belong to the category of thermal ablation, and both kill cancer cells through high temperature. The research of Medical College of Keio University in Japan proves that the ablation rate of argon-helium cryoablation knife for liver cancer is 96.5%. The experimental results of the 14th World Cryotherapy Conference and the 3rd China Tumor Targeted Therapy Conference held in Beijing, China from June 5th to October 6th, 2007 show that argon-helium cryotherapy is superior to radiofrequency ablation and microwave coagulation in reducing tumor residue and metastasis and prolonging the survival time of experimental rabbits. Radio frequency ablation and microwave coagulation have the same effect. Especially in the process of radiofrequency ablation and microwave coagulation, abdominal implantation and metastasis via needle track are easy to occur due to "boiling effect". Interventional therapy is an effective treatment for huge or multiple advanced liver cancer. Argon-helium cryoablation combined with interventional therapy can significantly improve the survival time of patients with huge or multiple intermediate and advanced liver cancer and reduce the recurrence rate. It has developed into the first choice for the treatment of advanced liver cancer. Two. Recognition of Argon-Helium Cryotherapy for Liver Cancer by the International Interventional Community At the annual meeting of North American Radiotherapy RSNA 9 1 held in Chicago, USA in June 2005, the effectiveness of Argon-Helium Cryotherapy for liver cancer, lung cancer, prostate tumor, kidney tumor, bone tumor, pelvic tumor and other fields was recognized. The fact that 12 radiation and interventional authority from the world's top cancer center chose argon-helium knife for treatment and conducted in-depth research proves that argon-helium knife is widely accepted by cancer circles and patients, and it will become a new choice for cancer treatment.