1963, the former Shanghai First Medical College purchased the first transmission electron microscope (Hitachi HU- 1 1A) of medical colleges in East China, and in the same year, the center laboratory of electron microscope of basic medical college was established. Since its establishment, the Electron Microscope Room has provided an open platform for ultrastructural research and observation for medical treatment, teaching and scientific research in schools and surrounding areas for 50 years. 198 1 was awarded the title of "model collective" by the Shanghai Municipal People's Government.
In the past 50 years, schools and local governments have continuously increased their investment in electron microscope rooms in basic medical colleges. 1977 bought Hitachi H-500 transmission electron microscope, 1985 bought JEOL 1200EX transmission electron microscope and Hitachi S-520 scanning electron microscope, 1999 bought Hitachi S-520 scanning electron microscope. In 2000, leaders of Fudan University, Ministry of Science and Technology, Equipment Department, Shanghai Medical College and Basic Medical College were all very concerned about the construction of electron microscope room. In 20 12, through the third phase of the "2 1 1" project, the latest transmission electron microscope of Feitenan AI G2 Spirit and field emission scanning electron microscope of Hitachi SU80 10 were purchased. At present, the resolution of transmission electron microscope electronic image reaches 4K&; Times4K, leading in China.
Long-term electron microscope practice has trained a group of teachers with rich experience in ultrastructural observation and technicians with experience in handling various complex biological samples. The current establishment is 4 teachers and 4 technicians. The Electron Microscope Room is also the only research and technical team in China that designs special sample preparation and observation strategies and methods for more than 200 kinds of cells in human or experimental animals. In addition to normal or pathological human ultrastructural specimens, the ultrastructural characteristics of the whole body organs and tissues of various experimental animals, such as rats, mice, guinea pigs, MICROTUS fortis, Mongolian gerbils, rabbits, beagles, cynomolgus monkeys and rhesus monkeys, were comparatively observed in the electron microscope room. In recent years, we have made a lot of knowledge and technical reserves in the electron microscopic observation of zebrafish, fruit flies, dragonflies, bees, birds, coronaviruses, influenza viruses, vaccines, stem cells, apoptosis and autophagy.
With the deepening of scientific research system reform, it is expected that the investment in large-scale equipment such as electron microscope will increase. The electron microscope room of basic medical college is determined and confident to provide the best platform for medical, educational and scientific research workers who are struggling at the forefront of scientific and technological innovation.
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