Chen Hongyuan's main deeds

1937 65438+February, born in Sanmen County, Zhejiang Province. 196 1 year, graduated from the chemistry department of Nanjing University, and stayed as a teacher. 198 1 ~ 1984, studying at the university of Mainz, Federal Republic of Germany, 1988, as a professor, was elected as an academician of China Academy of Sciences in 2006. Academician Chen Hongyuan has made great contributions to the research in many frontier fields, such as the basis of electroanalytical chemistry and its application in life science and material science. Several theoretical models of ultra-micro electrodes and their arrays are proposed, and the steady-state current solution of a series of complex systems coupled with multi-electrode processes in chemical reactions is solved. The influence of the overlap of diffusion layers of ultramicro electrodes on the total current of the array and its calculation formula are expounded. The relevant results have been written into the official technical report of the International Union of Pure and Applied Chemistry (IUPAC) officially adopted by its electroanalytical chemistry committee. A new method of functionalizing various electrode surfaces and forming various types of catalytic films is proposed. New materials for promoting electron transfer in protein were discovered, and a series of three-dimensional ordered bionic catalytic interfaces were constructed. Based on this, dozens of highly sensitive and selective detection methods for nucleic acids, protein (enzymes), coenzymes and bioactive small molecules, as well as related biosensor devices with stable and long life, have been established, which are widely used in biological substance detection and medical diagnosis. A series of new microfluidic chips and capillary electrophoresis electrochemical detection methods are proposed, which have strong anti-interference ability and high sensitivity, and broaden the application scope of electrochemical methods in chip laboratories. The established analytical methods and sensing devices have been widely cited and recommended by domestic and foreign counterparts.

Chen Hongyuan later served as deputy director of the Teaching Committee of Nanjing University, director of the Academic Committee of the School of Chemistry and Chemical Engineering, director of the Key Laboratory of Life Analytical Chemistry of the Ministry of Education, and director of the Institute of Analytical Science and the Institute of Chemical Biology of Nanjing University; He is currently a member of the Standing Committee of the Chemistry Department of China Academy of Sciences; Member of the Science and Technology Committee of the Ministry of Education and Director of the Department of Chemistry and Chemical Engineering; Member and judge of the National Supreme Science and Technology Awards Committee; Member and judge of the National Natural Science Award Committee; Vice Chairman of China Testing Association; Executive Director of chinese chemical society, Deputy Director of Analytical Chemistry Professional Committee; Chairman of Jiangsu Chemical and Chemical Society; Review leader of the Chemistry Department of the National Natural Science Foundation; Deputy Editor-in-Chief of Chemistry Journal of China University. in China. Editorial board or consultant editorial board of universities, China Science (in Chinese and English), Progress in Chemistry, Analytical Chemistry and Chromatography. He is the national representative of the Electrochemical Committee of the International Union of Pure and Applied Chemistry (IUPAC).

Adjunct or honorary professor of Peking University, Tsinghua University, China University of Science and Technology, Qingdao University of Science and Technology, East China University of Science and Technology, Northwest University, professor of Nankai University in Yang Shixian, director of Beijing National Laboratory of Molecular Science; Director of Academic Committee of State Key Laboratory of Electroanalytical Chemistry, Changchun Huaying Institute, China Academy of Sciences; Director of Academic Committee of State Key Laboratory of Biosensor and Chemometrics, Hunan University; Director of Academic Committee of Shaanxi Key Laboratory of Electroanalytical Chemistry.

Chen Hongyuan has successively won the second prize of the National Natural Science (2007) and the third prize (1982) 1, the first prize of the Ministry of Education (2006, 2006) and the National Science Conference Award 1. He has published more than 520 papers at home and abroad, compiled and translated 6 works and patented 5 items. Instructed and trained a group of doctoral students, doctoral students and master students. In 2004, he was rated as an excellent graduate tutor in Jiangsu Province and a national model teacher. In 2005, he was rated as a national advanced worker and won the national "May 1st" labor medal.

Chen Hongyuan's personality is very easy-going, and he often speaks with a faint smile. 1956, 18-year-old Chen Hongyuan was admitted to Nanjing University and then studied radiochemistry. As a student, Chen Hongyuan had a wide range of interests and broad vision. In addition to studying the knowledge of this major, he also dabbled in mechanics, mathematics, radio science and other disciplines, cultivated strong practical ability and scientific literacy, and laid a solid knowledge foundation for future scientific research work. In the fourth year of college, Chen Hongyuan entered the teaching and research section of analytical chemistry as a preparatory teacher, and embarked on a new professional road that later made him struggle all his life.

"When human beings have science and technology, there must be chemistry, and chemistry begins with analytical chemistry". Analytical chemistry is an important branch of chemistry, and it is a science that people obtain the composition, structure and information of substances through analysis. In modern science and technology, with the crossing of disciplines, analytical chemistry is more and more closely related to physics, life science, materials science, environmental science and energy science. It has become the foundation of modern science and technology and economic construction, and it is one of the main signs to measure the development of science and technology and the strength of national strength. Because of the development of capillary electrophoresis technology in analytical chemistry, the sequencing plan of human genome map was completed ahead of schedule.

Before 1990s, the main academic leader of analytical chemistry major in Nanjing University was Academician Gao Hong. Under the leadership of Mr. Gao and other predecessors, the doctoral program of this major ranks in the top three in China, and 1987 is rated as a national key discipline. In 1990s, the trend of sustainable development of this major was challenged due to the catch-up of brother colleges and the fact that Mr. Gao and other seniors left school or retired one after another. In the past ten years, Chen Hongyuan has invested a lot of energy in scientific research and teaching.

During the Seventh Five-Year Plan and the Eighth Five-Year Plan, the competition among domestic universities in China became increasingly fierce, which was the most difficult period for analytical chemistry. The scientific research work led by Chen Hongyuan encountered various difficulties, the most headache being the shortage of funds, the inability to buy necessary experimental equipment, and even the dilemma that scientific research could not continue. So, with the help of the overall strength of the school, with the support and help of his brother's laboratory and other departments of the school, he completed the research task that his laboratory could not complete. Whenever talking about this past, Professor Chen always said with emotion: "Nantah is a big family, and everyone is not isolated. Although we lack equipment, we have our brother's laboratory and school! "

Professor Chen Hongyuan has made a systematic and in-depth study on the frontier fields of electroanalytical chemistry and biomimetic catalysis, presided over and completed a number of major, key, general, doctoral and open laboratory projects funded by the Natural Science Foundation, and made outstanding contributions in the field of analytical chemistry. In the research of biocatalysis, supramolecular assembly and nano-electrochemistry, he successfully constructed a variety of efficient bionic catalytic interfaces and developed a series of electrochemical/biosensor devices. He also observed for the first time that surfactants promoted the electron transfer of hemoglobin, which improved its sensitivity by two orders of magnitude, from 10-5 mol/L to10-7 mol/L. Chen Hongyuan has published more than 330 papers, co-authored five books and cited more than 600 papers. His scientific research work has been highly praised by the scientific and technological circles. He has also won the National Science Conference Award, the first prize of the China University Natural Science Award of the Ministry of Education, the third prize of the National Natural Science Award and many provincial and ministerial awards.

It is particularly worth mentioning that Chen Hongyuan was in the early 1980s. I realized the importance of nanotechnology and did a lot of forward-looking work, which has always been valued by my peers. Anyone who studies microelectrodes knows that when the distance between two electrodes is less than a certain scale, they will interact. From 65438 to 0992, Professor Chen's research group made a systematic study on this phenomenon, and published an academic paper "Microelectrode Research: Shielding Effect of Microstrip Array Electrodes", which theoretically calculated this interaction and established a theoretical model. At the end of 2000, the international union of pure and applied chemistry, an authoritative academic institution in the international academic field, gathered a number of world-class experts and wrote a formal technical report "microelectrodes: definition, characteristics and application" in the name of the organization, which systematically summarized the development process of microelectrodes for more than 20 years. There are more than 6,543,800 papers on microelectrodes in the world, but this technical report only cites 365.438+0 most valuable references, among which Chen Hongyuan's paper is highly recommended.

Professor Chen is kind and humble. Whenever people talk about his scientific research achievements, he always smiles faintly. What he said is more about the support of schools and departments. He often said: "The school has created a very good environment for everyone's scientific research. The grade is not my own, I just played the role that a subject leader should play. The results are everyone's, the hard work of the participants, the result of sincere unity, and the result of the support of schools and departments. "

Academician Chen Hongyuan has made a series of important achievements in biocatalysis, supramolecular assembly and nano-electrochemistry. Over the past 40 years, it has also made important contributions to the cultivation of senior talents. He observed for the first time in the world that surfactants promoted the electron transfer of hemoglobin, which improved its determination sensitivity by two orders of magnitude. So far, he has presided over and successfully completed 26 major and key projects, doctoral programs, "863" projects and international cooperation projects of the National Natural Science Foundation. He has won many awards such as the National and Jiangsu Science and Technology Progress Award.