Ethylene oxide sterilization equipment maintenance management and quality control, improve the quality of medical sterilization. Methods Using process monitoring, chemical monitoring and biological monitoring methods, the performance and sterilization effect of ethylene oxide sterilization equipment was tested...
How long does ethylene oxide gas sterilization take for chemical monitoring Strong penetration of the sterilized article can reach the deep part of the article, which can kill most pathogenic microorganisms, including bacterial propagules, spores, viruses and fungi. Gas and liquid have strong microbial killing effect, to gas effect is stronger, so more use of its gas. It is currently believed that ethylene oxide kills microorganisms due to its ability to occur with microbial proteins, DNA and RNA non-specific alkylation. Take proteins as an example, the carboxyl, amino, sulfhydryl and hydroxyl groups on proteins are alkylated, so that the normal biochemical reaction and metabolism of proteins are blocked, resulting in the death of microorganisms. Ethylene oxide is hydrolyzed and converted into ethylene glycol, which also has some bactericidal effect. Indications This product is widely used in medical disinfection and industrial sterilization. Commonly used in foodstuffs, textiles and other methods can not be disinfected for heat unstable drugs and surgical equipment such as gas fumigation disinfection, such as leather, cotton products, chemical fiber fabrics, precision instruments, biological products, paper, books, documents, some drugs, rubber products. Usage and dosage Because ethylene oxide is explosive and flammable, the concentration in the air over 3% can cause combustion and explosion. Generally use CO2 or halothane as diluent to prevent combustion and explosion, the preparation is 10% ethylene oxide mixed with 90% CO2 or halothane. Disinfection must be carried out in closed containers. More commonly used are fixed container disinfection method, disinfection bag disinfection method, plastic curtain disinfection method and automatic control disinfection box disinfection method. All of the above methods are required to ensure the reliability and repeatability of sterilization,