The development of Shandong Qidu Pharmaceuticals Co.

●In 1976

June, the company was established in Jingzhong Commune, Linzi District, with the name of Zibo Linzi Pharmaceutical Factory, which was a social factory.

●1977

February, Shandong Provincial Revolutionary Committee Health Bureau, Bureau of Commerce, Chemical and Petroleum Industry Bureau to (77) Lu Wei drug No. 9 approval issued "on the consent of Linzi Pharmaceutical Factory included in the production plan of the approval of the reply", the production of the enterprise formally included in the plan of Shandong Province.

In March, Tobing Shuang became secretary of the party branch.

In April, 500ml I.V. (sodium chloride injection) workshop was successfully put into production.

●1978

January, the small injection (hydrocortisone) workshop was successfully put into production.

In March, ammonium chloride API was successfully put into production.

August, Zhang Xianggui became the factory director.

November, Linzi District Revolutionary Committee with (78) No. 98 approval issued "on the Linzi Pharmaceutical Factory to the district community joint office of the approval, the nature of the enterprise from the community office to the district community joint office, according to the management of the district's collective enterprises.

December, small injections of analgin successfully put into production.

●1979

October, Linzi Pharmaceutical Factory won the first place in the total score in the quality evaluation of the province's infusion industry organized by Shandong Provincial Pharmaceutical Corporation, and won the award for five consecutive years.

In October, Jiang Danfu became the factory director.

●1982

In March, the syrup workshop was successfully put into production.

●1983

April, tincture workshop was successfully put into production. There were red mercury solution, methyl violet solution and iodine tincture.

In May, the 250ml infusion workshop was successfully put into production, filling the blank in the province.

●1984

October, 500ml glucose sodium chloride injection was honored as a high-quality product of Shandong Province.

●1985

March, Jiang Danfu and Zhang Bingzhi became the secretary of the party branch and factory director respectively.

In May, the groundwater was polluted and the enterprise was forced to stop production.

December, the enterprise in the drilling of water quality is still unqualified in the case of long-distance pulling of water to start production self-help, up to three years.

December, the general branch of the factory was awarded the provincial advanced group branch.

●1986

In March, the Municipal Construction Committee issued the "Approval for the Construction of Linzi Pharmaceutical Factory in Xindian" with the approval letter No. (86) 40, approving the relocation of the enterprise to Xindian, with the area of the factory of 72.46 acres.

In May, the carton workshop was successfully put into production.

In September, the enterprise started the construction of the first phase of the new factory in Xindian.

●1987

September, the enterprise implemented the factory director's responsibility system and the tenure target responsibility system of the factory director.

●1988

February 1988

Phase I of the new plant was completed, and the enterprise management organization and the first and fourth workshops were relocated to the new site.

In March, Wang Huaiyuan, deputy secretary of Zibo municipal party committee and mayor of Zibo, visited the factory.

In May, the first and fourth workshops were put into production.

In June, the name of the enterprise was changed to Shandong Linzi Pharmaceutical Factory, and the original factory of Jingzhong was named Linzi Pharmaceutical Factory.

December, with the Qilu Petrochemical more than three years of groundwater pollution disputes have results, was awarded 1 million yuan.

December, the Labor Department of Shandong Province approved 260 people, the backbone of production and management of the plant, to be converted into peasant contract workers.

●1990

March, the enterprise was awarded the title of municipal advanced enterprise and municipal civilized factory by the municipal government.

In April, Wang Xiaozhou became the factory director.

In April, Qi Moujia, the director of the State Pharmaceutical Administration, visited the factory.

October, Metronidazole G Injection was honored as a high-quality product of Shandong Province.

October, sugar powder workshop was put into production.

In November, the enterprise was approved by the municipal government to be upgraded from a district collective small (I) type enterprise to a medium-sized (II) type enterprise.

●1991

August, Li Jinsong became factory director and secretary of the Party branch.

December, the enterprise was released from the nature of the district and community joint operation, and was completely transferred to the district.

In December, the annual infusion production exceeded 10 million bottles for the first time.

●1992

In November, the enterprise was upgraded from a medium-sized (second) type enterprise to a medium-sized (first) type enterprise with the approval of the provincial economic committee and the provincial statistics bureau.

●1993

March, Li Zhentao became the factory director and secretary of the party branch.

April, the enterprise was rated by the National Bureau of Statistics as one of the 500 largest pharmaceutical industry enterprises in China.

December, the enterprise implemented the shareholding system pilot, the establishment of Shandong Linzi Pharmaceutical Company Limited, and later withdrew from the pilot.

●1994

September, the enterprise implemented the asset management responsibility system.

●1995

March, the enterprise set up the general party branch, Li Zhentao also served as secretary of the general party branch.

●1996

September, the new product Blue Scutellaria Oral Liquid, jointly developed with Shandong Medical University, obtained the new drug certificate and production approval. The product filled the domestic blank. It was later transferred to the outside world.

●1997

April, Zheng Jiaqing and Zhang Fuquan became the factory director and the secretary of the party branch respectively.

In November, the enterprise shut down the powdered sugar workshop, which had been losing money for many years.

●1998

In June, Zheng Jiaqing became secretary of the general party branch at the same time.

In June, the company held a general meeting on the founding of the joint-stock cooperative system and implemented the reform of the property rights system. Zheng Jiaqing was appointed chairman and general manager, and Cui Pingan was appointed director.

August, the first and second workshop passed the GMP standard inspection and acceptance in Shandong Province.

December, the enterprise was restructured in that year, and the loss was reversed in that year, ending the situation of long-term loss.

●1999

In March, Mr. Zhang Sizhong, vice president of China Chemical Pharmaceutical Industry Association, and Mr. Shen Xianji, secretary-general of China Chemical Pharmaceutical Industry Association, came to the factory for research.

In December, a 5,000-square-meter living building was built to alleviate the problem of staff housing difficulties.

●2000

In March, the new cerebrovascular drug Bufumai (Bufodil Hydrochloride Sodium Injection) obtained the new drug certificate and production approval. Later, the extended-release tablet dosage form was added. This product filled the domestic blank, and was honored as the national key new product and the symbol product of Shandong Province.

In May, Shandong Dongbo New Drug R&D Center was jointly established with Shandong Medical University.

December, the first and second workshops obtained the national GMP certificate.

In December, the total profit and tax of the year exceeded 10 million yuan for the first time.

●2001

January, the new broad-spectrum antibacterial drug Dinosin (Levofloxacin Hydrochloride Sodium Injection) obtained the new drug certificate and production approval. The tablet dosage form was added later.

In June, Li Min, the director of Shandong Province Drug Administration, accompanied by Wang Mouchang, the director of Zibo Drug Administration, came to inspect the factory.

December, the additional annual output of 30 million bottles of infusion production plant (three workshops) successfully put into production and successfully passed the national GMP certification.

●2002

February, the company set up a party committee, Zheng Jiaqing as party secretary, Zhang Zhaoli as deputy secretary.

In February, Yan Qijun, the secretary of Zibo Municipal Party Committee, visited the enterprise.

August, the registered trademark of Qidu brand was awarded the title of famous trademark of Shandong Province.

●2003

January, the comprehensive preparation workshop (tablets, granules, dispersions, syrups) completed the technological transformation and successfully passed the national GMP certification.

July, the enterprise was assessed as Shandong High-tech Enterprise by Shandong Science and Technology Department.

December, the enterprise was evaluated as the Provincial Contract and Credit Keeping Enterprise by Shandong Industrial and Commercial Bureau.

In December, the annual infusion production exceeded 100 million bottles for the first time.

●2004

April, Shandong Donglin Drug R&D Center was jointly established with Shandong University of Traditional Chinese Medicine.

In May, the enterprise drug research center was recognized as a provincial enterprise technology center by the provincial economic and trade commission.

In May, the enterprise system was standardized as a limited liability company, and the enterprise name was changed to Shandong Qidu Pharmaceutical Co. Zheng Jiaqing was appointed as chairman and general manager.

In May, the first holding subsidiary of the enterprise, Zibo Jingrui Packaging Co.

In May, Liu Huiyan, deputy secretary of Zibo Municipal Party Committee and mayor of Zibo, visited the company.

In May, the company was appraised as a key high-tech enterprise of the National Torch Program by the Ministry of Science and Technology of the People's Republic of China.

In May, Zheng Jiaqing was elected as the director of Provincial Pharmaceutical Society.

June, the API (ammonium chloride) workshop completed the technical transformation and successfully passed the national GMP certification.

In June, the party committee of the company was honored as the advanced grass-roots party committee of Zibo city by the municipal party committee and the municipal government of Zibo city.

In September, the company was elected as the director unit of China Chemical Pharmaceutical Industry Association, and Zheng Jiaqing was elected as the director.

●2005

January, the company's new annual production capacity of 15 million bags of non-PVC flexible packaging infusion production workshop (seventh workshop), the new annual production capacity of 120 million bottles of glass bottle infusion production workshop (fourth workshop), and the renovation of the comprehensive preparation workshop (capsules, anti-tumor infusion) passed the national GMP certification.

In January, the first workshop was awarded the honorary title of Provincial Science Workshop by the Provincial Science Association.

In May, Zheng Jiaqing was honored as one of the Ten Outstanding Youth in Zibo City.

July, the enterprise was evaluated as the backbone enterprise of national biomedical industry base by the Ministry of Science and Technology of the People's Republic of China.

In September, Tolansetron Hydrochloride API and injection, a new drug for chemotherapy and antiemetic, obtained new drug certificate and production approval. This product fills the domestic blank.

September, Qidu Pharmaceuticals Science and Technology Park began construction, urban leaders Yue Changzhi, Duan Liwu, Xie Weijun and other leaders attended the groundbreaking ceremony.

In November, Zhang Jianguo, the secretary of Zibo Municipal Party Committee and the director of Standing Committee of Municipal People's Congress, came to inspect the construction site of Qidu Pharmaceuticals Science and Technology Park.

In December, Lou Hongxiang, vice president of Shandong University and dean of School of Pharmacy, came to the company for research.

December, the company was named provincial youth civilization by *** Youth League of Shandong Province.

December, the company fully completed the China Chemical and Pharmaceutical Industry Association assigned the butyl plug experimental tasks and according to the plan to fully complete the butyl plug switching work.

December, the annual infusion production exceeded 200 million bottles (bags) for the first time, ranking first in Shandong Province and fifth in China in the infusion industry.

●2006

February, the APIs (lipoic acid, temsirolimus, tolansetron hydrochloride) successfully passed the national GMP certification.

February, the company held a budget management meeting, marking the initial integration of enterprise management into the budget management track.

In March, Metadoxine API and tablets, a new drug for liver disease, obtained new drug certificate and production approval. This product filled the domestic blank.

April, the company officially launched the ERP application system.

In May, the pilot production of biopharmaceutical--adenosylmethionine was successful.

In May, the first workshop of Qidu Pharmaceuticals Science and Technology Park was put into production.

June, the company held the celebration of the 30th anniversary of the founding of the factory.

In June, Feng Bo, the vice general manager of the company, was honored as "Outstanding Young Intellectuals of Zibo City" and was awarded third-class merit.

August, the company obtained the production approvals for the specifications of compound amino acid, fat milk injection and fluconazole capsule.

In August, the company's Metadoxine API passed the GMP certification work.

In September, the company's 101 workshop passed GMP certification. It marks the development of Qidu Pharmaceuticals has entered a new historical period.

In September, Workshop 103 passed GMP re-certification.

October, the company was awarded as Shandong Province Consumer Satisfaction Unit by Shandong Province Sixth Consumer Association.

October, the company was recognized by the National Bureau of Statistics as one of the top ten enterprises with innovation ability in the national chemical drug preparation manufacturing industry.

November, the company developed a biotechnology product adenosylmethionine pilot test success.

December, the company's R&D center was recognized by the Shandong Provincial Science and Technology Department as the Shandong Provincial Plasma Substitute Engineering and Technology Research Center.

●2007

January, the company's "Propionyl-L-Carnitine Synthesis Process" won the national invention patent.

In February, Zhang Zhaoli, deputy secretary of the Party Committee, was awarded the title of "Labor Medal for Revitalizing Zibo".

In March, the fourth shareholders' meeting of the company was successfully held, which produced the new board of directors and supervisory board. Mr. Zheng Jiaqing was appointed as the chairman of the board.

April, the company's "Metadoxine Tablets and its preparation method" was awarded the patent certificate of invention by the State Intellectual Property Office.

In April, Mr. Zheng Jiaqing, the chairman of the board, was awarded the title of "Zibo Model Worker".

In April, the company was honored by Zibo municipal party committee and municipal government as "Zibo Top 100 Excellent Enterprises in Industry", and the chairman of the board of directors, Mr. Zheng Jiaqing, was honored as "Top 100 Excellent Entrepreneurs in Industry in Zibo".

In June, the company was appraised as "Shandong Province grass-roots party building demonstration point" by the Organization Department of Shandong Provincial Party Committee.

July, the construction of Workshop 201 in Science and Technology Park was successfully completed and put into trial production.

August, the company was recognized by Shandong Provincial Science and Technology Bureau and Shandong Provincial Intellectual Property Office as "China Patent Shandong Star Enterprise".

September, the company was honored by the State Administration for Industry and Commerce as "National Enterprise of Abiding by Contracts and Keeping Credit".

In October, the construction of 601 workshop started.

October, the company's products "Aminotyrosine Sodium Chloride Injection" and "Metadoxine Tablets" successfully passed the GMP certification.

October, the construction of the staff apartment, staff restaurant and multi-function hall in the company's science and technology park began.

In December, Mr. Zheng Jiaqing, the chairman of the board of directors of the company, was elected as a deputy to the Zibo City People's Congress.

In December, Liu Yanhua, vice minister of the Ministry of Science and Technology, came to inspect the company.

In December, the company's product "GANXIN" was evaluated by the Ministry of Science and Technology of the People's Republic of China as a national key new product.

●2008

February, 405 workshop and 406 workshop passed GMP re-certification.

In February, the company was honored by the municipal party committee and the municipal government as one of the "Top 100 Excellent Enterprises in Zibo Industry" and "Top 50 Taxpaying Enterprises in Zibo".

In March, the 201 workshop of the company successfully passed the GMP certification.

April, the company was elected as the director unit of China Chemical Pharmaceutical Association, and the chairman of the board, Mr. Zheng Jiaqing, was elected as the director again.

April, the company's employee assistance foundation was established.

In May, Feng Bo, the vice general manager, was honored as "Top Ten Outstanding Youth in Linzi District".

In June, the company successfully passed the national AAA level measurement certification.

In June, the company was elected as the vice chairman of Infusion Liquid Committee of China Chemical Pharmaceutical Industry Association.

July, the company passed the national standardization good behavior AAA grade enterprise certification, ISO9001 international quality management system certification and ISO14001 international environmental management system certification.

In August, Mr. Zheng Jiaqing, the chairman of the board of directors, was honored with the title of "Zibo City's Ten Most Responsible Enterprises".

In October, the staff apartment, staff restaurant and multifunctional hall of the company's science and technology park were put into use.

October, the synthesis technology of propionyl-L-carnitine inner salt in the project of "R&D of raw materials and preparations of propionyl carnitine chloride", which was jointly developed by the company and Shandong University, was awarded the invention patent by State Intellectual Property Office.

In November, Workshop 301 passed GMP certification.

In December, the trademarks of "Qidu Brand" and "Bufumai" were honored as famous trademarks of Shandong Province.

In December, the company was awarded the first batch of graduate employment demonstration base by Zibo Personnel Bureau.

In December, the project of "Metadoxine Tablets" was listed as a national torch program by the Ministry of Science and Technology of the People's Republic of China.

●2009

January, Jingrui Packaging's application for registration of aluminum-plastic combination cap for infusion bottles passed the municipal and provincial production site assessment.

In March, the company was honored by Zibo Science and Technology Bureau as the advanced group of intellectual property rights in Zibo.

In March, the product Metadoxine Tablets was awarded the first prize of Science and Technology Progress Award by Zibo Science and Technology Bureau.

In April, the company was honored as one of the city's top 100 excellent enterprises in industry by Zibo Municipal Government, and the chairman of the board of directors of the company, Mr. Zheng Jiaqing, was honored as an excellent entrepreneur.

In May, the company was honored as "Advanced Collective for Adverse Drug Reaction Monitoring" by Zibo Drug Administration.

In May, the company's R&D products "Warm Palace and Pregnant Children Capsule", "Tongkou Nasal Inflammation Tablet" and "Nilgorin for Injection" have obtained the approval number of drugs.

In September, the trademark "Qidu" was awarded as "Famous Trademark of China" by Zibo City Court.

November, 202 workshop, 302 workshop, 102 workshop successfully passed the national GMP certification; 104 workshop, 307 workshop successfully passed the national GMP certification review.