According to the survey in 20001year, the mortality rate of the three major killers is 62.47% in cities and 50. 19% in rural areas. At present, the mortality rate of the three major diseases accounts for 64% of the total mortality rate. How to treat the three killers depends mainly on self-care, health education and health promotion. We must resolutely implement the policy of "prevention first" so as not to get sick, get sick less and get sick later.