What happened to cholestasis of pregnancy? Bile is the secretion of gallbladder, and bile is a component of digestive juice. Generally, cholestasis will cause abnormal stool or urine color, not necessarily cholestasis. It is best to do liver function and B-ultrasound examination.
Intrahepatic cholestasis of pregnancy is caused by abnormal liver function, which leads to intrahepatic cholestasis. Bile acid in liver function increased significantly, leading to some complications. It is often accompanied by itching and discomfort, which can endanger the health of the fetus in severe cases.
Cholestasis during pregnancy, a disease that only occurs during pregnancy and subsides after termination of pregnancy. It has itching before jaundice appears, and jaundice is mostly mild or moderate, far less than itching. In the second and third trimester of pregnancy, the whole body itches first, which is more serious at night, and there is no specific rash. It is suggested that pregnant mothers should do further liver function examination according to the doctor's advice, and should not take it lightly, and then do scientific and standardized treatment according to the results. In addition, we should pay attention to a light diet, do not eat greasy, spicy and irritating food, and maintain adequate sleep and a happy mood.
The normal value of total bile of pregnant women is a little higher than that of normal people, which is generally1~12 μ mol/L. When the total bile acid of pregnant women is slightly higher, it has little effect. However, if the bile acid of pregnant women is too high, it may have a certain impact on the fetus, and the total bile acid of pregnant women will return to normal after giving birth to their babies; If pregnant women have hepatobiliary diseases before pregnancy, the increase of total bile acids is directly proportional to the degree of liver cell damage.
The treatment plan for cholestasis of pregnancy is 1, rest, high-risk pregnancy management, systematic monitoring, active symptomatic liver protection treatment and timely termination of pregnancy.
2. Drug therapy
(1) The traditional Chinese medicine for soothing the liver, preventing miscarriage and benefiting gallbladder has a good effect.
(2) cholestyramine, 8 ~ 12g/d, taken orally for 2 ~ 3 times.
(3) phenobarbital 0.03g, taken orally, 3 times a day.
(4) Vitamin C, vitamin B6 and vitamin K 1 were supplemented and added to glucose solution for intravenous drip. Prevent bleeding during and after delivery.
(5) Liver-protecting drugs, such as Gantaile.
3. Obstetric treatment/
(1) Strengthen monitoring, and NST should monitor the fetus at least once a week.
(2) induced labor should be carried out after 37 weeks of pregnancy, and in principle it should not exceed the expected date of delivery.
(3) If abnormal fetal heart rate is found or fetal distress is suspected during pregnancy or labor, it is often necessary to end delivery by cesarean section.
(4) Estrogen is prohibited during pregnancy and postpartum lactation.