Specific circumstances:
165438+ 10 month 18 physical examination report showed that carcinoembryonic antigen (CEA qualitative) was negative. Because she has been bleeding in the stool for more than half a year, Ms. Chen is very uneasy. On June165438+1October 2 1 day, she went to a public hospital for an examination, and the result was "rectal cancer".
165438+1October 22nd, the detection result of carcinoembryonic antigen (CEA) of Ms. Chen in the Second People's Hospital of the city was 6.79 ng/ml (the normal value was 0-5ng/ml). Further examination revealed that Ms. Chen was in IIB stage of rectal cancer. Ms. Chen believes that Mei Nianda Health has made mistakes in the physical examination process, but Mei Nianda Health insists that she is innocent.
In June last year, 1 1, the year before last, 44-year-old Ms. Chen, under the arrangement of the company's trade union, went to the Health Hongling Branch of Mei Nianda for a physical examination. 2065438+0165438 On June 8, 2006, three laboratory examination reports of cancer in the United States showed that Ms. Chen's AFP (AFP qualitative), carcinoembryonic antigen (CEA qualitative) and EB virus antibody were all negative.
Because of repeated bloody stool for more than 6 months, Ms. Li suspected that there must be something wrong with her body. After completing the annual physical examination arranged by the company, he went to Shenzhen Second People's Hospital on June 5438+065438+1October 2 1 at his own expense, and was diagnosed as "rectal cancer" and was hospitalized on the same day. 165438+1On October 22nd, she had an examination of alpha-fetoprotein (AFP)+ carcinoembryonic antigen (CEA)+CA 199 in the Second Hospital. The detection result of carcinoembryonic antigen (CEA) was 6.79 ng/ml (normal value was 0-5ng/ml).
During the hospitalization, after laboratory tests and X-ray examination, Ms. Chen was discharged from the hospital and was diagnosed with rectal cancer (stage IIB). Southern Reporter saw from the pathological examination report presented by Ms. Chen that the size of rectal tumor was about 5.1cm * 3.5cm *1.6cm, and the tumor invaded the periintestinal fat.
"I also know that being positive does not mean cancer. For example, enteritis and cholecystitis will also be positive, and non-invasive mucosa will also be negative. The problem is that I am in the middle stage of rectal cancer, which has invaded the mucosa and the result is negative. If you don't go to the hospital for another examination, isn't it necessary to delay treatment? " Ms. Chen expressed doubts about the quality of the physical examination of Mei Nianda.
American health response: carcinoembryonic antigen is clinically false negative.
Mr. Yang, the medical director of Mei Nianda Health Shenzhen Branch, responded to this. He introduced that carcinoembryonic antigen is a broad-spectrum tumor marker with poor specificity. The content of normal people such as smokers, pregnant women and some inflammatory serum will also increase. There are false positives in clinic, that is, people who are positive for carcinoembryonic antigen are not necessarily cancer patients; There are also false negatives in clinic, that is, those with negative carcinoembryonic antigen may not be cancer patients. Carcinoembryonic antigen is only an indicator of auxiliary diagnosis, and its main significance lies in monitoring the curative effect of cancer.
Mr. Yang pointed out that the amount of carcinoembryonic antigen examined by Ms. Chen in Shenzhen Second People's Hospital on 20 1 165438 was 6.79ng/ml, which was less than 2ng/ml higher than the reference range of Shenzhen Second People's Hospital (0-5ng/ml). However, before seeing a doctor, 20110, 18, the unit chose the qualitative examination of carcinoembryonic antigen, and the result was negative.
Expert: No cancer was found in the physical examination. It's possible.
In the middle stage of rectal cancer, the physical examination institutions checked that all three tumors were normal. Can a physical examination detect cancer? Jiang, director of surgery at Shenzhen Hospital of Traditional Chinese Medicine, said in an interview with the media that there are many methods and items of physical examination at present, and everyone's physique is very different. It is normal for cancer patients not to be diagnosed by physical examination. Moreover, the physical examination report is only a reference for disease treatment, and false positive and false negative cases of cancer are not uncommon in clinic.