The pharmacological effects of drugs for promoting blood circulation and removing blood stasis can be summarized as follows:
Drugs for promoting blood circulation and removing blood stasis generally have the functions of dilating peripheral blood vessels and increasing blood flow function of organs. 22 kinds of drugs for promoting blood circulation and removing blood stasis have effects on femoral artery blood flow and vascular resistance. It can increase femoral artery blood flow and reduce vascular resistance to varying degrees. Drugs for treating blood stasis generally have the effect of relaxing blood vessels, such as pangolin, leech, zedoary, motherwort, peach kernel, etc., which have the effect of dilating femoral artery. In addition, there are drugs for removing blood stasis and resolving hard mass, drugs for promoting blood circulation and removing blood stasis, and drugs for dilating femoral artery, among which drugs for removing blood stasis and resolving hard mass have the strongest curative effect. However, this study also shows that Rhizoma Corydalis, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, etc. It has a more prominent role in dilating coronary arteries.
Angina pectoris and acute myocardial infarction of coronary heart disease have typical symptoms of blood stasis, and drugs for promoting blood circulation and removing blood stasis have good curative effect in the treatment of coronary heart disease. Many cases can prove that drugs for promoting blood circulation and removing blood stasis can increase coronary blood flow and improve myocardial oxygen supply function, such as Salvia miltiorrhiza, Ilex pubescens, Carthamus tinctorius, Leonurus japonicus, Angelica sinensis, Paeonia lactiflora, Corydalis yanhusuo, etc. Compound salvia miltiorrhiza, red peony root, safflower, etc. Spatholobus suberectus, Spatholobus suberectus, Radix Curcumae, Olibanum, Myrrha, Sanguis Draxonis, Pollen Typhae and Tongmailing all have similar or greater influences.
Chronic hepatitis and liver cirrhosis often have blood stasis, such as pain in the liver area, dark skin and abdominal distension. The high-frequency impedance diagram of liver area shows that the pulsatile blood flow in liver area of patients with blood stasis is often lower than that of healthy people, and the outflow resistance is higher than that of healthy people. After promoting blood circulation and removing blood stasis, with the improvement of liver function, the pulsating blood flow in liver area increased and the outflow resistance decreased. The decrease of blood flow and cerebral blood flow, the improvement of blood circulation stasis and the improvement of cerebral circulation in patients with cerebrovascular disease. In addition, compared with patients with thromboangiitis obliterans and chronic obstructive pulmonary disease, the blood flow of diseased organs can also be increased after blood stasis, blood circulation and blood stasis.
Promoting blood circulation and removing blood stasis is one of the commonly used methods to treat acute abdomen with combination of traditional Chinese and western medicine. It has obvious effects on early inflammation and different types of inflammatory infiltration. From the therapeutic effect of drugs for promoting blood circulation and removing blood stasis on experimental inflammation, it can be seen that its anti-inflammatory mechanism may be due to reducing the permeability of capillaries in inflammatory areas and reducing inflammatory exudation; At the same time, it can improve the blood circulation of local tissues and promote the absorption of inflammatory exudates. In addition, some drugs for promoting blood circulation and removing blood stasis also have certain antibacterial and anti-infection effects, such as Salvia miltiorrhiza and Paeonia lactiflora can inhibit the growth of Staphylococcus aureus, while drugs such as Paeonia lactiflora and Chuanxiong can inhibit the growth of intestinal pathogenic bacteria.