Secretion, after which about 70% of growth hormone is produced in deep sleep, and the amount of secretion is positively correlated with the length of deep sleep. Both human and animal experiments have found that injecting growth-promoting hormone can reduce awakening time and increase deep sleep time. After 30 ~ 40 years old, the average secretion of growth hormone decreased by 3 ~ 4 times within 24 hours; Therefore, the decrease of growth hormone produced during sleep at this time may play an important role in the aging process of the body. The effect of adrenocorticotropic hormone is just the opposite, that is, when the secretion of growth hormone increases, the secretion of cortical hormone decreases. After the growth hormone secretion decreases, the cortical hormone secretion increases relatively, causing shallow sleep.
The growth and aging of the body are also related to the pineal gland, which is also called melatonin. Melatonin is a tryptamine-containing hormone secreted by the pineal gland, and its secretion amount and secretion time are regulated by the supraoptic nucleus of the hypothalamus, that is, the awakening/sleep rhythm biological clock according to the light and dark cycle: the secretion amount increases after nightfall and reaches the peak at midnight; During the day, when the body is exposed to light, its secretion will decrease proportionally. The main function of melatonin is related to the regulation of awakening/sleeping rhythm and body temperature. The increase of melatonin secretion at night is related to the decrease of body temperature, both of which are beneficial to sleep.
In nature, wild animals and primitive human beings are made at sunrise and rest at sunset. One species after another.
(2) Preserving the life span of brain energy, the pineal gland will naturally follow the process of aging, atrophy and calcification. At the same time, the biological clock depends on the energy of its brain decline, which is mainly related to the deep sleep period in NREM sleep. NREM sleep is a kind of melanin code. In this kind of sleep, the brain is relatively quiet and directs the various systems of the body to enter the aging process in an orderly way. If the biological clock fails prematurely, all the organs will fail with it. At this stage, parasympathetic nerve activity is dominant, pulse slows down (decreasing lO-30 times per minute), systolic blood pressure decreases and contracts; On the contrary, if the biological clock stays in the process of delaying aging, all organs will also delay aging. Low (10-30mmHg), slow breathing, decreased basal metabolic rate and brain metabolism (10% ~ 15%), and cerebral blood flow (5) increased the immune mechanism of the body.
Decreased (25%), the contents of nucleic acid and protein in brain increased. It is obvious from PET examination that both cellular immunity and humoral immunity are related to sleep. For example, Born found that during sleep, the metabolic rate of monocytes and natural glucose decreased significantly, which indicated that the blood flow in the brain decreased. Therefore, sleep can also preserve the energy of the brain, reduce the number of killer cells (NK cells) and lymphocytes, and restore the body function of interleukin -2(IL-2) produced by T cells. At present, it is found that cytokines related to sleep include interleukin (IL) and tumor necrosis factor (TNF). TNF) and interferon (IFN) for memory consolidation. The phases of REM sleep and NREM sleep are changed in normal sleep, which not only ensures that the body and brain get enough rest, but also ensures that these cytokines have the function of regulating immune response. The sleep-inducing effect of IL- 1 was first discovered. IL- 1 not only restores immune function and stores energy, but also maintains and develops brain function, which is of great significance for exerting the best response during awakening. It can also regulate sleep, appetite, brain development and function under physiological conditions. During awakening, the most active function of cerebral cortex is prefrontal function, such as attention, logical thinking ability and IL-6 secreted by immune cells and nerve cells, which is related to the physiological or psychological stress of the body. It is not the ability to respond to language, the ability to plan behavior, the ability to respond to environmental changes and the ability to respond quickly. Endogenous IL-6 induced by some experimental stimuli is secreted most in young healthy people at night, which becomes the data of brain immune response to stress. It is proved that the prefrontal function will be damaged just because of one night's sleep deprivation. In America, there is a medium for spreading information. All of the above explain the influence of sleep on immune function. In addition,. McFarlane found that 57% of truck drivers died of brain function decline caused by lack of sleep, and there was a coordination effect between secretion-thermoregulation and brain function activity, accounting for 10% of general car accident deaths, and the annual economic loss reached $56 billion. And the impact of the space shuttle challenger tragedy; On the contrary, the disorder of awakening/sleep rhythm and sleep disorder can also cause immune-neuroendocrine-thermoregulation and the accident of Three Mile Island nuclear power plant, which are also related to lack of sleep and untimely response of relevant personnel. Functional changes lead to pathological processes. Memory is another important function of the brain. For example, after learning a new thing, deliberately depriving the subject of
Sleep, we can find that lack of sleep obviously affects the memory ability of new things. Jocelyn told 48 college students, half male and half female. A: The basic methods of emotional control mainly include the following aspects: students conduct experiments, let them walk between the bookshelves in the library according to the prescribed route, and remember one of the prescribed routes after many exercises.
Don't be too hard on yourself.
After that, let half the students go home to sleep, and the other two and a half students are deprived of sleep for one night because of entertainment and other activities; A week later, they will receive treatment.
After the second interview, the correct rate of path recognition in the sleep deprivation group was significantly lower than that in the normal sleep group, indicating that the memory of spatial orientation should not expect too much of others. To influence, so sleep has the function of consolidating memory. In addition, dreaming in REM sleep is the reproduction of memory information. 3 channel your anger. Hennevin used some electrophysiological and behavioral experiments to prove that REM sleep can rearrange the reproduced memory information. Theory, form new neural connections, and have an impact on the awakening period, improve the effectiveness of memory information processing in the awakening period.
(5) temporarily avoid.
(4) promoting physical growth and delaying aging.
6 find someone to talk to.
The relationship between sleep and growth hormone is considered to be the most detailed study on the relationship between sleep and hormone secretion.
For example. The secretion of growth hormone has obvious rhythm, and the secretion of human growth hormone is mainly related to the deep sleep during NREM sleep. Close. VanCarter said that from childhood to * *, from the first time you fell asleep, there was a growth hormone score of 1. Self-cultivation.
Third,
Fourth, (1) promote the development and development of brain function.
The development of brain function is mainly related to rapid eye movement sleep. The proportion of rapid eye movement sleep in infants can be as high as 50%, which is more than double that of adults. For patients with Alzheimer's disease, it is obviously reduced or even disappeared; These facts show that sleep plays an important role in the development of brain function. The exact mechanism of rapid eye movement sleep promoting the development of brain function is not clear. Maquet examined the brain positive ion emission scanning imaging (P'ET) of healthy people who were sleeping. The results showed that during REM sleep, the blood flow of pontine tegmentum, left thalamus, bilateral amygdala, anterior cingulate cortex and right insula increased obviously, while the blood flow of other parts such as prefrontal cortex, superior gyrus, posterior cingulate cortex and anterior cingulate cortex decreased. Using histochemical technique, it can be clearly seen that the glucose metabolism rate in the medial hypothalamic nucleus, cingulate gyrus, habenular nucleus and reticular structure of the brain during REM sleep is significantly higher than that during waking. Mirmiran even thinks that REM sleep accounts for a high proportion of infant sleep, which is a compensation for too little awakening time; The length of REM sleep is an index of brain development.