Chronic gastritis can be divided into superficial gastritis and atrophic gastritis according to pathological types:
Superficial gastritis is a common phenomenon. If there are no obvious clinical symptoms, there is no need for excessive attention and treatment. If there are obvious symptoms, it is recommended to go to the hospital for clinical treatment in time.
Atrophic gastritis may have the possibility of gland atrophy and canceration, so it is suggested to do symptomatic treatment and regular follow-up examination.
Intestinal metaplasia is the abbreviation of intestinal metaplasia, which means that normal gastric mucosa epithelium is replaced by intestinal epithelium. Simply put, under normal circumstances, our organs all have their own functions. Gastric mucosal epithelial cells with gastric acid secretion function grow on the surface of stomach, and intestinal mucosal epithelial cells with secretion and absorption function grow on the surface of intestine. However, when gastric mucosal cells are seriously damaged, the epithelial structure of gastric mucosa will change to some extent. The longer it grows, the more it looks like a child with intestinal mucosa. Appearance observation is like the intestinal mucosa is in the wrong position, but the structure that should grow in the intestine appears on the gastric mucosa, just like a grass grows a tree and the tree appears.
Intestinal metaplasia of gastric mucosa is more common in chronic gastritis. In fact, what is closely related to gastric cancer is not atrophic metaplasia, but a kind of high-grade intraepithelial neoplasia called atypical hyperplasia, also called atypical hyperplasia, which is an abnormal proliferative lesion of gastric mucosal gland cells. So now it is known that if the patient is atrophic gastritis and intestinal metaplasia after endoscopic pathological examination, there is no need to worry. If dysplasia is found, it is necessary. Generally, simple metaplasia does not need to be too nervous. Gastroscopy is reviewed once a year, and active intervention is needed when progress is found.
The treatment of intestinal metaplasia is as follows: 1. We should avoid mental stress, quit smoking and limit alcohol, try to avoid food that is irritating to the stomach, and actively treat chronic tonsillitis, paranasal sinusitis, dental caries and throat infection.
2. Dietotherapy should be adopted. The diet of patients with chronic superficial gastritis should be light, regular, regular and quantitative, and avoid foods that are too sour, too spicy, cold and rough.
Chronic gastritis should pay attention to the following matters. If you have chronic gastritis, don't eat foods that are too irritating, too spicy, too cold, too hot and too sour. Don't touch alcohol and tobacco. Eat when you should eat and sleep when you should sleep. Another point that patients with chronic gastritis must pay attention to is to take medicine correctly, because 60% of patients are infected with Helicobacter pylori, and chronic gastritis will not be cured unless it is removed.
In addition to these, we should also pay attention to the best gastroscope every other year to find early gastric cancer in time, so as not to regret it when it is late. Please pay attention to this. Patients with gastritis should avoid smoking, drinking and drinking coffee. Especially avoid spicy food.
A good life comes from a healthy beginning, a healthy beginning and professional media of health science! What does it mean for father's gastroscopy to diagnose chronic gastritis with intestinal metaplasia? Hello, I'm Dr. Huang Zhiyan, and I'm glad to answer your question.
Intestinal metaplasia means that epithelial cells of gastric mucosa are replaced by intestinal epithelial cells, that is, epithelial cells similar to small intestine or large intestine mucosa appear in gastric mucosa, which is a common pathological change of gastric mucosa and is found in many chronic gastric diseases, especially in the elderly.
Intestinal metaplasia is often accompanied by chronic gastritis, especially chronic atrophic gastritis. Due to the development of gastroscope technology, especially the application of gastroscope, a large number of discoveries and studies of early gastric cancer, it is considered that intestinal metaplasia of gastric mucosa is closely related to gastric cancer.
However, there is no need to be too nervous. Not all intestinal metaplasia will become cancerous. According to the current research, incomplete and large intestinal metaplasia are easy to become cancerous, while small intestinal metaplasia generally does not become cancerous, and there is still a gap between intestinal metaplasia and canceration for several years. Therefore, during this period, as long as active treatment and good review are enough.
First of all, we must eradicate Helicobacter pylori, which is the number one accomplice of chronic gastritis. If the patient is infected with Helicobacter pylori, it is necessary to eradicate Helicobacter pylori, which can relieve symptoms and cure gastritis.
Secondly, acid suppression therapy is suitable for patients with hyperacidity, and proton pump inhibitors, such as omeprazole, pantoprazole and rabeprazole, are preferred. It should be noted that chronic atrophic gastritis patients take acid inhibitors orally for a long time, which will aggravate gastric mucosal atrophy. Control and improve bile reflux, suitable for bile reflux gastritis.
In daily life, we should pay attention to improving our lifestyle, specifically, we should not smoke or drink, have three meals regularly, stimulate our diet with spicy food, avoid being cold and greasy, pay attention to vegetarian food collocation, avoid overeating, and supplement vc, selenium and folic acid appropriately. Use aspirin and other drugs with caution. Do not stay up late, exercise properly, etc.
Of course, some young people will indeed be reversed through good maintenance, but it is good for the elderly to take care of them and not aggravate their illness. Don't think that taking two pills can completely cure rejuvenation. If there is Helicobacter pylori infection accompanied by intestinal metaplasia, it is suggested to eradicate Helicobacter pylori. The time of gastroscopy of intestinal metaplasia should be analyzed according to the size and scope of intestinal metaplasia, the degree of gastric mucosal atrophy, whether there are intraepithelial neoplasia and dysplasia (the size and height of weeds).
The general principle is that if it is just intestinal metaplasia, the gastroscope should be checked in the second year, and if there is no problem, it should be checked every 2-3 years. Such as tumor formation, dysplasia, etc. May be reviewed once every six months to one year. If there is serious tumor formation or dysplasia, it can be surgically removed under gastroscope. If most people are removed, they will not become cancerous, just like normal people.
In short, it is active treatment and regular review. Don't be too nervous, don't take it lightly, and keep an optimistic attitude.
I'm Dr. Huang Zhiyan, and I'm committed to explaining complicated and difficult disease knowledge in plain language to help you manage your body well. Your praise is my greatest motivation! In addition, if your family is also troubled by intestinal metaplasia, please forward this article to them! In the examination of stomach diseases, the results of gastroscopy diagnosis are reliable. Being diagnosed as chronic gastritis with intestinal metaplasia means that chronic gastritis exists for a long time and turns into chronic atrophic gastritis, and the epithelial cells of gastric mucosa have undergone abnormal structural changes during the long-term stimulation and repeated repair of inflammation.
Intestinal metaplasia of chronic gastritis, mainly seen in type B atrophic gastritis, refers to a pathological change in which glandular epithelial cells of gastric mucosa are replaced by intestinal epithelium containing goblet cells. Due to the atrophy of gastric mucosa glands, gastric acid and pepsin secretion will be reduced, and symptoms such as loss of appetite, indigestion, epigastric discomfort, dull pain, emaciation and anemia will appear.
No matter what kind of atrophic gastritis occurs, we should actively treat it to control the changes such as dysplasia. Treatment is usually to remove the causes (Helicobacter pylori infection, bile reflux) and long-term application of bismuth potassium citrate, bismuth pectin, aluminum magnesium carbonate and other gastric mucosal protective agents, as well as pancreatin tablets, multi-enzyme tablets, vitamins and other drugs to help food digestion, reduce the digestive burden of the stomach, and promote the recovery of gastric mucosal function.
Thanks for reading!
The concept of epithelial metaplasia belongs to the category of pathology, and if it is more detailed, it belongs to the category of cell adaptation and injury. So what exactly is metaplasia? What is the relationship between chronic gastritis and intestinal metaplasia? What is the harm of metaplasia? What should I do after intestinal metaplasia is diagnosed? Next, Dr. Hu will give you a brief answer in combination with pathology, internal medicine and preventive medicine.
What is metaplasia? Our cells are always faced with changes in the internal or external environment, and always show different degrees of coping styles in the face of these changes and stimuli. These counterparts include both morphological changes in appearance and metabolic and functional changes. Metaplasia, on the other hand, is a special type that cells and tissues adapt to changes. Metaplasia represents the process in which one mature cell type is replaced by another in the lesion.
What are the hazards of intestinal metaplasia? Therefore, intestinal metaplasia and bronchial squamous metaplasia are closely related to the evolution of precancerous lesions. However, bronchial squamous metaplasia is related to lung squamous cell carcinoma, and gastric intestinal metaplasia is related to gastric adenocarcinoma.
What is the cause of gastric metaplasia? The forest cell metaplasia of bronchus and lung is more related to smoking, and the continuous stimulation of mucosa by damaging substances such as arsenic and aldehyde is the basis of metaplasia. So what factors can lead to intestinal metaplasia of gastric mucosa in the stomach?
In a word, intestinal metaplasia is caused by the stimulation of long-term inflammation, which damages the original gastric mucosa epithelium. In order to better adapt to the stimulation of inflammation, intestinal epithelium will replace the original gastric mucosa epithelium. With the long-term existence of Helicobacter pylori infection and other inflammations, if biochemical stimuli are not thoroughly treated and controlled, the malignant transformation after intestinal metaplasia will lead to precancerous lesions, and the physiological disorder of apoptosis and proliferation will lead to cancer.
Can intestinal metaplasia be reversed? Can it be prevented? At present, whether intestinal metaplasia is reversed is still controversial, or there is not enough evidence to support the reversal of intestinal metaplasia. Once intestinal metaplasia occurs, it is generally difficult to reverse it, taking Helicobacter pylori as an example. Helicobacter pylori is usually the initial factor of intestinal metaplasia. After active treatment to eradicate helicobacter pylori, intestinal metaplasia has hardly been reversed. However, after correcting Helicobacter pylori, it can delay the diseases represented by chronic gastric atrophy and greatly reduce the incidence of gastric cancer.
Except that intestinal metaplasia is extremely difficult to reverse, there is no exact prevention and treatment method for intestinal metaplasia at present, so how should patients face treatment after being diagnosed with intestinal metaplasia?
What should I do after the diagnosis of intestinal metaplasia? It is concluded that metaplasia is a manifestation of the adaptation of tissues and cells to internal and external stimuli, and its essence is that one mature cell replaces another. However, intestinal metaplasia of gastric mucosa is usually associated with precancerous lesions. If the stomach is not completely cured for a long time due to Helicobacter pylori infection and inflammation, intestinal metaplasia is easy to cause cancer. But it is still a long process from intestinal metaplasia of gastric mucosa to gastrointestinal cancer. If intestinal metaplasia has been diagnosed, it is necessary to correct the cause in time and actively follow up to rule out the possibility of inducing malignant transformation.
The intestinal tract loses its absorption function.
Answer according to the questions raised: The first thing that patients and their families need to pay attention to is whether the patient himself has just had a simple gastroscopy instead of a pathological biopsy. Because only by clearly knowing which tests have been done can we know whether it is really diagnosed as intestinal metaplasia and accurately judge the severity of the disease.
What is intestinal metaplasia? Is it serious?
Intestinal metaplasia is a serious type of chronic gastritis, which will get worse with age, especially for middle-aged and elderly people. Intestinal metaplasia, atrophy and dysplasia (that is, atypical hyperplasia mentioned in gastroscopy report) are called precancerous diseases of gastric cancer, among which dysplasia is precancerous lesions of gastric cancer.
Chronic gastritis is a disease development process, mainly including chronic non-atrophic gastritis (that is, chronic superficial gastritis commonly seen on gastroscope) and chronic atrophic gastritis. In the process of chronic gastritis developing into gastric cancer, there are two viewpoints: precancerous diseases and precancerous lesions: precancerous diseases include chronic atrophic gastritis, gastric polyps, gastric ulcer and gastric stump cancer with or without intestinal metaplasia; Precancerous lesions and dysplasia (atypical hyperplasia).
Generally speaking, at present, as long as people who have done gastroscopy, they basically have examination reports of chronic non-atrophic gastritis or chronic superficial gastritis. If there are no discomfort symptoms such as stomach pain, abdominal pain and stomach discomfort, they do not need to receive medical treatment.
If the results of gastroscopy show chronic atrophic gastritis or intestinal metaplasia or dysplasia, we should attach great importance to it. This concern is not blind. First of all, I suggest that if you simply do gastroscopy, the report results will appear atrophy, intestinal metaplasia and other words, and you have unwell symptoms. First of all, you must not be too anxious because this result is not accurate enough, but you need to take drugs to alleviate the discomfort at this stage. Secondly, please remember to tell the doctor who opened the examination report to bring the gastroscope and pathological biopsy together next time, so that the accurate results can be obtained by combining the results of gastroscope and pathological biopsy, and the doctor will give a suitable treatment plan according to the specific situation. Therefore, it must be remembered that if gastrointestinal problems are found, they must not be disturbed, and gastroscopy and pathological biopsy must be checked together.
At the same time, if the pathological biopsy results are indeed atrophy or intestinal metaplasia, no matter which age group needs attention, routine treatment is needed. Elderly people with perennial stomach diseases are more likely to find atrophy or intestinal metaplasia, because atrophy and intestinal metaplasia are related to age, and all aspects of the body functions of the elderly also shrink with age. It is not necessary to be too alarmed to find atrophy or intestinal metaplasia, but conventional treatment can be used.
Hello, intestinal metaplasia describes a state change of gastric mucosa, that is to say, gastric mucosal epithelial cells that should have grown in the stomach have now become intestinal epithelial cells, so it is called intestinal metaplasia.
Intestinal metaplasia can generally be divided into mild, moderate and severe, often accompanied by chronic gastritis, especially chronic atrophic gastritis. However, intestinal metaplasia is atypical if it develops again, and the canceration rate of atypical hyperplasia is about 40%.
3. Intestinal metaplasia is more common in the high incidence area of gastric cancer than in the low incidence area of gastric cancer.
Therefore, from this perspective, it is suggested that active intervention, early treatment and prevention before illness are the best policy. I wish you a speedy recovery ~
Lifeway public health believes that gastric mucosa has changed at this time, especially after the invention of gastroscope, more and more people have been diagnosed as epithelial metaplasia, which provides a good help for diagnosis and treatment. This epithelial metaplasia has a certain correlation with gastric cancer. The incidence of gastric cancer in patients with intestinal metaplasia has increased, and intestinal metaplasia is considered as one of the "precancerous lesions" of gastric cancer. Some people think that once intestinal metaplasia occurs, does it mean that one foot has entered the death gate of gastric cancer? Actually, it is not. Some studies have found that intestinal metaplasia is reversible. Measures such as lowering the pH value of gastric juice and eradicating Hp infection are beneficial to prevent gastric mucosal atrophy and intestinal metaplasia. Even if the patient is diagnosed with metaplasia, there is no need to be nervous. According to research statistics, the probability of intestinal metaplasia and cancer is 5%. In other words, 100 chronic gastritis with intestinal metaplasia, 5 people developed into gastric cancer. This probability is not high.
Life-oriented public health advice should try to remove possible incentives in life. At ordinary times, we should develop good dietary hygiene habits, avoid mental stress, and quit smoking and drinking. We should eat more fresh vegetables and less food that irritates the gastric mucosa, such as strong coffee, spicy food, cold food, overheated food and coarse food, avoid mildew, pickled, smoked and fried food, and limit the intake of salt. Take some drugs according to the doctor's advice to control the progress of the disease and reduce the risk of gastric cancer. Some bioactive antioxidant vitamins can reduce the risk of gastric cancer, such as vitamin C, folic acid, allicin, tea polyphenols and so on.
Chronic gastritis is a very common chronic inflammatory disease of gastric mucosa, generally including chronic superficial gastritis and chronic atrophic gastritis.
Chronic superficial gastritis generally does not need to take stomach medicine or other special treatment. As long as we pay attention to diet, give up drinking and eat less spicy and irritating food, gastritis can be obviously improved.
We should attach great importance to chronic atrophic gastritis. Although there are different opinions about chronic atrophic gastritis, they are all general and not specific. If simple atrophic gastritis generally does not need special treatment, intestinal metaplasia of gastric mucosa is not terrible.
Physiologically, gastric mucosa and intestinal mucosa have different morphological structures and functions. They perform their respective duties, coordinate with each other, and jointly complete the digestive function. In other words, intestinal mucosal cells should not appear in gastric mucosa. If intestinal epithelial cells appear in gastric mucosa, it is called intestinal metaplasia of gastric mucosa.
Intestinal metaplasia of gastric mucosa is a pathological development stage of chronic atrophic gastritis. It can be divided into small intestinal metaplasia and large intestinal metaplasia. If we pay attention to the usual diet or give active treatment, most patients with intestinal metaplasia of gastric mucosa will not continue to develop in a bad direction and present a stable state.
Intestinal metaplasia of gastric mucosa can further develop into atypical hyperplasia of gastric mucosa (or atypical hyperplasia). It is said that metaplasia of large intestine is easier to turn into atypical hyperplasia than metaplasia of small intestine. This stage is not good, because atypical hyperplasia of gastric mucosa is a precancerous lesion of gastric cancer.
At this stage of atypical hyperplasia, besides abstinence from alcohol and changing bad eating habits, active treatment is also needed. For example, oral drugs to eliminate Helicobacter pylori in the stomach, as well as other stomach drugs, can block its development chain.
In addition, it is necessary to pay attention to strict gastroscopy follow-up. Generally, it is required to review the gastroscope once a year, find cancer early, and actively operate.
Brief description:
Your father's should be atrophic gastritis; Atrophy and intestinal metaplasia often go hand in hand.
Atrophy refers to the thinning of gastric mucosa and the decrease or disappearance of glands attached to it due to various reasons;
Intestinal metaplasia refers to intestinal cells taken by the body to repair itself after gastric mucosa is damaged, which is called intestinal metaplasia.
It is generally believed that atrophy and intestinal metaplasia belong to precancerous lesions, which need active treatment and regular gastroscopy.