Does anyone know the impact of heavy metals on human health and the "dose-effect" relationship of the impact? Websites and magazines are ok ~

The harm of heavy metals to human body is common:

Lead: It harms human brain cells, leading to cancer and mutation.

Mercury: It sinks directly into the liver after eating, which is harmful to the brain and vision. Natural water containing 0.0 1 mg per liter of water is highly toxic.

Chromium: It will cause numbness of limbs and mental abnormality.

Arsenic: It will make the skin pigmentation and lead to abnormal keratinization.

Cadmium: causes hypertension and cardiovascular and cerebrovascular diseases; Destroy bone calcium, resulting in renal insufficiency.

Aluminum: long-term accumulation, causing mental retardation to children; Leading to memory loss in middle-aged people; Causing dementia in the elderly.

Cobalt: It can cause radiation damage to the skin.

Vanadium: It hurts the heart and lungs and causes abnormal cholesterol metabolism.

Antimony: With arsenic, silver jewelry will turn brick red and be radioactive to the skin.

Selenium: If you take too much, you will get sick.

Thallium: It can make people suffer from polyneuritis.

Manganese: Too much will make people hyperthyroidism.

Tin: Lead is an important component of the ancient giant poison' pigeon', which solidified into pieces after entering the abdomen and fell to death.

Lead invading the body will also enter the brain tissue with the blood flow, damage cerebellum and cerebral cortex cells, interfere with metabolic activities, and lead to insufficient supply of nutrients and oxygen. Due to lack of energy, the endothelial cells of small capillaries in the brain swell, the lumen narrows, the blood flow stagnates, and vasospasm leads to cerebral anemia and brain edema, which develops into hypertensive encephalopathy. It is worth noting that tetraethyl lead has a great toxic effect on brain tissue. In the production environment, if the concentration of tetraethyl lead in the air reaches 100mg/m3, people can be poisoned by inhaling 1 hour.

Chromium-containing compounds have local effects on skin and mucosa, which can cause dermatitis and perforation of eardrum. People who are often exposed to low-concentration lead will have symptoms such as headache, dizziness, fatigue, memory loss, insomnia, constipation and abdominal pain when the blood lead reaches 60 ~ 80ug/ 100ml.

When methylmercury accumulates in the body for 25mg, there is abnormal perception, 55mg has walking disorder, 90mg has pronunciation disorder, and 170mg leads to hearing loss. Different forms of heavy metals have different effects on human body. When mercury vapor invades respiratory tract, it can be completely absorbed by alveoli and transported to the whole body through blood. Metal mercury in blood can enter the brain tissue through the blood-brain barrier, and then it is oxidized into mercury ions in the brain tissue, which accumulates in the brain tissue and damages the brain tissue. Inorganic mercury (HgCl2) entering human body often causes kidney injury and mild liver injury.