After menopause, due to the deterioration of ovarian function, women can no longer produce estrogen and lutein, which will lead to menopausal symptoms of hormone deficiency, such as hot flashes, palpitations, emotional changes, insomnia and so on. Women with severe menopausal symptoms can be effectively relieved by estrogen therapy. For women with uterus, lutein must be given at the same time to protect the endometrium (mixed hormone therapy). As for women whose uterus has been removed, if estrogen is needed to improve menopausal symptoms, there is no need to give lutein.
Does taking hormones increase the risk of breast cancer? The general public may have heard that taking hormones may increase the risk of breast cancer. This mainly comes from the clinical trial report published by American Women's Health Initiative (WHI) in 2002, which was published in JAMA in July 2002. 288:32 1-333)。
This report has two main points:
1. Women take mixed hormones (estrogen+lutein) for more than 4 years, and there are 8 cases of breast cancer per 10000 women every year (the increase probability is actually not high, only slightly increased).
2. Women who have taken mixed hormones for less than 4 years or have no uterus and only use estrogen will not increase the incidence of breast cancer.
It is inferred from the results of this report that long-term uninterrupted use of lutein (more than 4 years) may be one of the factors leading to the increase of breast cancer. It is worth noting that lutein used in clinical trials in 2002 is synthetic lutein, which is different from natural lutein.
There are two kinds of oral natural lutein in Taiwan Province Province, which are fat-soluble. If taken directly, it will be destroyed by gastric acid, so it cannot be effectively used. It must be packaged into a capsule of micronized natural lutein through a special process to avoid the destruction of gastric acid, and it can only be absorbed and utilized after reaching the intestine. At present, the name of oral micronized natural lutein is Utrogestan? (You Jietong? ); Another kind of natural lutein can be absorbed directly by mouth after being irradiated by special light, which changes the three-dimensional structure of natural lutein (slightly curved), but does not affect the biological and physiological effects. (get a fetal bulge? )。
In some countries, these two kinds of natural lutein are only 1 species, while in some countries (such as the United States), there are no two kinds, while in Taiwan Province Province, China, there are two kinds.
(Source: provided by Dr. Wang Xinshi)
Natural lutein does not increase the risk of breast cancer. The research team of the National Institute of Health and Medicine in Villerouf, France, followed 80,377 women who had stopped menstruating and taken hormones for more than 8 years, and analyzed the incidence of breast cancer after taking different lutein. It was found that oral micronized natural lutein (Youjietong? ) Women will not increase the incidence of breast cancer; Take Du Harston? (get a fetal bulge? ), although slightly higher than the use of oral micronized natural lutein (Youjietong? ), but compared with women who take other synthetic lutein, it is obviously lower. The research results were published in the journal Breast Cancer Research and Treatment (2008; 107: 103- 1 1 1)。
Unveiling the Myth of Breast Cancer According to the data released by the National Health Agency of the Ministry of Health and Welfare of Taiwan Province Province, there are 188 ~ 194 cases of breast cancer every year among every 65,438+10,000 women in Taiwan Province Province. Although the general public often intuitively think that taking hormones is related to the occurrence of breast cancer, this is only a small part of the causes of breast cancer. Hormones are not the initial or inducing factors of breast cancer, but the amplification and enhancement factors. In other words, women who would not have breast cancer would not have breast cancer if they took hormones. As for women with breast cancer, taking hormones will accelerate their growth. If they don't take hormones, breast cancer will happen later, but it will still happen.
Moreover, different hormones have different effects on inducing breast cancer, and some hormones do not cause breast cancer. Genetic factors are one of the real factors that induce breast cancer. In addition, environmental hormones, lack of exercise, overweight and obesity are all important factors inducing breast cancer (table 1). These factors are much more influential than hormones used to treat menopausal symptoms, but they are often ignored, especially environmental hormones. For example, plastic cups filled with cold drinks and ice products contain a lot of environmental hormones.
(table 1. Image source: provided by Dr. Wang Xinshi)
Hormone therapy that does not increase the risk of breast cancer According to the results of clinical trials, hormone preparations that can be used at present are sorted out. Hormone therapy to reduce the risk of breast cancer is as follows:
1. Estrogen only: only for women with hysterectomy.
2. Estrogen+oral micronized natural lutein (Youjietong? ): Suitable for women with uterus.
3. Estrogen +Duphaston? (get a fetal bulge? ): Suitable for women with uterus.
Supplement: BLACKPINK Tong? (Femoston conti？ ) is estrogen +Duphaston? (get a fetal bulge? ) can increase the convenience of taking (for example, taking 1 tablet every day).
Most hormone therapy drugs should be paid at their own expense. It is recommended to consult a specialist to find a treatment that suits their own situation. ※.
& lt This column reflects experts' opinions and does not represent our position >