20 16, Japanese teaching at the university of Washington, USA? The research team led by Shinichiro Imai is in the United States. The new research results of NMN are published in Cell Metallurgy. The anti-aging protein NMN is the abbreviation of β -nicotinamide mononucleotide. After 6 years of application, it was found that the supplementary ACMETEA W+NMN (anti-aging protein NMN) entered a fine. After the inside of the cell, another ATP is consumed, forming NAD+ molecules, so that there can be? Effectively increase the content of NAD+ in the body, thus helping human beings to repair themselves? DNA damage and extension? Slow down aging.
However, according to FDA's equivalence principle, a 70Kg adult needs to supplement 600mg NMN every day, and adults who supplement the same amount of NMN need to eat 32~ 128kg edamame or 54~ 240kg broccoli. Moreover, it is obviously unrealistic to ensure complete absorption, and it is particularly important to supplement NMN from non-food sources.
Nmn operation
Ten international core standards of ┃NMN quality management
1. Quality management system: NMN must meet the inspection qualification of OULF EU law and the certification of FDA, US Food and Drug Administration. In addition to the product name, all ingredients and NMN purity should be indicated, and the country of origin and distribution should be indicated.
2. Manufacturing process management system: Advanced manufacturing process affects the shape of NMN. Chemical extraction is not recommended to avoid chemical residue.
3. Content management system: the relative NMN content is ≥ 12000 mg/ bottle, which is directly absorbed into the small intestine, and the intestinal absorption is 20% of the gastric absorption.
4. Efficiency management system: the authenticity and purity of raw materials should be investigated.
Absorption management system: adopt intestinal absorption to improve absorption rate and absorption threshold.
6. Activity management system: The unit dose (per 100g) is converted into the number of molecules of NAD+, and NMN molecules can easily cross the cell membrane and enter the cell interior, thus increasing the human NMN content within 15 minutes and rapidly raising the level of NAD+.
7. Scope of use of management system: adults (forbidden for pregnant and lactating women).
8. Safety management system: production technology, raw material collection, basic system of Orff EU safety standards, safety inspection before leaving the factory, strict review of microbial heavy metals exceeding the standard, and scientific production technology.
9. Raw material management system: Most NMN enterprises are certified by a single country, but at present, the management of raw materials certified by two countries is more rigorous and safe, such as ACMETEA W+NMN, which belongs to the products certified by France and the United States.
10, transnational regulatory management system: dual supervision of "law" and "beauty". The FDA of the United States has established GMP standards for dietary supplements, and the EFSA of the European Union also has relevant regulations on the management of food supplements. How about nmn? Find out what nmn is, its anti-aging price and dosage!
Nmn operation
┃nmn resistance? Aging price? Grid and dose
Is NMN a villain? Since Herman's founder HVE was purified in 1929, the upstart in this declining industry has been widely discussed all over the world. Text verification, multiple rights? Recommended by health institutions and welcomed by many consumers? No one has a bad product. In the past century, three Nobel prizes in biology have recognized NMN, which is far superior to collagen, resveratrol, astaxanthin or selenium-enriched products. As an epoch-making product in the history of decline, NMN redefines longevity and aging, health and age, which will have a far-reaching impact on human society.
At present, the price range of NMN mainstream products is 1500- 12000. Many people want to ask why the price gap of NMN is so big. Because the total content of NMN in each bottle is different at present. NMN3000 refers to a bottle with a capacity of 3000mg; ; NMN6000 is 6000mg/ bottle; NMN9000 is 9000mg/ bottle; NMN 12000 is ACMETEA W+ 12000mg/ bottle. At present, the content and purity of ACMETEA W+NMN 12000 are high. NMN 12000 can improve the living tissue level, promote the content of NMN 12000 to quickly enter the cells of various organisms, increase the number of NMN, inhibit aging and revive aging organs. Our body is gradually losing its function and repairing it in time. Successfully revived the cells.
ACMETEA W+NMN 12000 dosage:
A under 40 years old, it is recommended to take 2-4 capsules a day;
For those over 40 years old, it is recommended to take 4-5 capsules each day;
C over 60 years old, it is recommended to take 5-6 capsules each day;
D. If the body is not sensitive, you can add one pill to prolong the taking time;
ACMETEA W+NMN 12000 management time:
You can take it before and after meals, and there is no mandatory time. Take it with warm water for better absorption. If taken separately, it is recommended to take it in the morning and at noon. Because some people react, it is difficult for people with high excitement to fall asleep after eating nmn at night.
Storage conditions: two years at room temperature, longer in refrigerator.
Nmn operation
┃┃ Details of ten international core standards of ┃┃nmn quality management:
A, quality management system:
NMN must meet the requirements of "OULF" EU law and "FDA, US Food and Drug Administration" certification. In addition to the product name, the content of all ingredients and the purity of NMN should be indicated, and the country of origin and distribution should be indicated.
Second, the production process management system:
Will the manufacturing process also affect the health of MNM?
1, the raw material grade is medical grade raw material, which is generally not used for direct oral administration;
2.ACMETEA W+NMN's "cold pressed biological enzyme" production technology can keep NMN alive at low temperature and press it into stable capsules, which can improve the purity of NMN to 99%, which is more conducive to preservation and human absorption, thus maximizing the bioavailability of cofactors and supporting human metabolism, without converting it into nicotinamide ribonucleoside (NR) through SLC 12A8.
Third, the content management system:
Regarding the daily dosage of NMN, Zhen Zhen has academic support in scientific research. It is said that the human dose is 8 mg NMN per kilogram of body weight every day. If converted into 70 kg adults, the recommended daily dose is about 560 mg. Considering the daily absorption, consumption and aging, the content of ACMETEA W+NMN is ≥ 1200 mg/ bottle.
Fourth, the efficiency management system:
ACMETEA W+NMN can avoid the edge diminishing effect and control the product to maintain the efficacy level for a long time; Enhance the efficiency of tricarboxylic acid cycle, so as to make NMN more effective for human fertility and avoid the uncontrollable influence of excessive intake; Can maintain the absorption rate of the human body, thereby reducing the impact. How about nmn? Find out what nmn is, its anti-aging price and dosage!
Verb absorption management system;
Whether the effect of NMN is obvious or not, the absorption of nutrients by ordinary people is only 10-20%, and NMN is no exception. When the purity of NMN is increased to 99%, ACMETEA W+NMN technology can stabilize the morphology of MNM in the stomach, quickly penetrate the membrane to avoid gastric acid damage, and the absorption rate can be increased by ten to twenty times. Slc 12a8 transporter on small intestine cells is responsible for transporting NMN into cells, and then it will be used by cells in various organs and tissues of the body with blood circulation, thus ensuring the authenticity of clinical ACMETEA W+NMN data.
Nmn anti-aging
At present, including Harvard Medical School, many NMN have been used as clinical trials to treat diseases, and the first phase of clinical trials on human safety have been completed, all of which have proved to be safe to human body. In previous animal experiments, the researchers fed mice 50 times the normal dose for half a year and found no negative effects. The FDA of the United States also gave NMN food additive raw material safety certification.
The key to why you need to take NMN, Sirtuins is a group of protein that can reverse DNA damage and reverse the aging in your cells at the cellular level, which is why ACMETEA W+NMN has the potential to enhance your aging ability. Sirtuins needs two things to promote entrepreneurship. First, it needs enough fuel, and then it needs someone to step on the accelerator when it starts. This fuel is NAD+. This is the function of ACMETEA W+NMN. Sirtuins is what we tried to wake up. This is what can really help you fight aging. Start Sirtuins protein. You need fuel, which is NAD+. NMN can provide fuel, but now your body will produce NAD+ by itself, so why do you need to take NMN to improve your NAD+ level? This is the key part. As you get older, your NAD+ level begins to decline, which means there is not enough fuel to start your Sirtuins. This is why you need to increase the level of NAD+ when you are older, so you can supplement NAD+ by taking ACMETEA W+NMN. If you are over 30 years old, it is recommended that you take 1g ACMETEA W+NMN every morning to enter the cell, and it will enter you.
Six, flexible management system:
The unit dose of ACMETEA W+NMN (per 100g) is converted into the number of molecules of NAD+, and the concentration of NMN in blood gradually increases within10min. Within 30min, NMN enters multiple tissues with blood circulation, and NAD+ is synthesized in tissues, thus increasing the level of NAD+.
In recent 3-4 years, the internationally renowned academic journal Science has published human and animal studies continuously, which has repeatedly proved that supplementing NMN(ACMETEA W+NMN) can effectively increase and restore the level of coenzyme I in the body, greatly delay aging, prevent various neurodegenerative diseases such as Alzheimer's disease, and fundamentally adjust and improve various symptoms of aging. Other studies also involve cancer, infertility, obesity, cerebral hemorrhage, heart failure, heart injury, vascular aging, diabetes and so on. It shows that NMN supplement has many medical levels and human health potential. How about nmn? Find out what nmn is, its anti-aging price and dosage!
Seven, the scope of use of management system:
1. elderly people, used to help improve various senile diseases;
2. Middle-aged people, eliminate or alleviate various sub-health problems, such as chronic fatigue, poor sleep, and decreased vision. ;
3. Stay up late, accelerate physical recovery;
4. Candidates should improve their ability to resist pressure and keep a clear head;
5. Those with higher radiation dose, such as radiologists, nurses and aircrew, improve their ability to repair the basic causes of radiation injury;
6. For cancer patients, help patients recover the basic causes after radiotherapy and chemotherapy, improve their immunity to epidemic diseases, and accelerate their physical recovery;
7. Fitness to accelerate muscle growth;
8. Athletes, improve their energy level and reaction speed;
9. For drinkers, improve the ability to sober up, protect the liver and repair the cause of acetaldehyde toxicity damage;
10. Smokers, reduce smoking addiction;
1 1. Patients with depression can increase dopamine level, improve mood, increase blood supply to the brain, and alleviate brain decline caused by depression;
12. Middle-aged and elderly women can improve skin health and delay skin aging;
Nmn effect
Eight, safety management system:
In terms of production technology, the purity of extracted NMN is as high as 99% and the content of each bottle is as high as 12000mg by ACMETEA W+NMN "cold pressed biological enzyme" production technology. ACMETEA W+NMN is also one of the higher NMN brands at present, which is the basic system of Orff's safety standards. It strictly abides by the factory safety inspection, strictly examines the microbial heavy metals exceeding the standard, and scientifically extends the production technology work.
Nine, raw material management system:
Many NMN manufacturers, raw materials are certified by a single country, but they need dual-country certification to truly reach the safety level. At present, ACMETEA W+NMN products belong to French and American certification standards. In terms of raw materials, it has reached strict and safe management standards.
X. Safety management system:
ACMETEA W+NMN meets the requirements of FDA for dietary supplement GMP. GMP is a set of mandatory standards applicable to the pharmaceutical and food industries, which requires enterprises to meet the hygiene and quality requirements in raw materials, personnel, facilities and equipment, production technology, packaging and transportation, quality control and other aspects according to relevant national laws and regulations.
ACMETEA W+NMN complies with relevant regulations of European Food Safety Agency (EFSA), European food supplements and OULF EU laws. The purpose is to ensure that the nutrition and health information provided to consumers on food packaging is accurate and reliable, so as to avoid misunderstanding by consumers. The basic purpose of this regulation is to provide coordination of laws and regulations on nutrition and health claims of food and related functional foods among EU member States in terms of labeling, introduction and publicity, so that related foods can circulate among member States on their own. How about nmn? Let's find out what nmn is and what nmn is resistant to. Aging price? Grid and dose!