2. Nicotine is fat soluble. After inhaled into the lungs, it can quickly pass through the blood and cross the blood-brain barrier to reach the central nervous system and produce biological effects, affecting the central nervous system.
3. After nicotine enters the human body, the peripheral nicotine blood vessels contract, the heart beats faster, the blood pressure rises, the breathing becomes faster, the mental state changes (such as emotional stability or excitement), and platelet aggregation is promoted, which is the main accomplice of cardiovascular diseases such as cardiovascular obstruction, hypertension and stroke.
Extended data:
Introduction to the principle of nicotine production effect;
1, the function of nicotine is the result of its ability to combine with some receptors in the brain. When nicotine binds to nicotinic acetylcholine receptors (nACHRs) in the brain, it will stimulate the release of "neurotransmitters".
2. When nicotine regularly stimulates nACHR receptors, the body will reduce the number of receptors and react with acetylcholine itself, which means that the same amount of nicotine no longer has the same effect.
3, affect serotonin, affect people's mood GABA(γ- aminobutyric acid), and reduce the active glutamate of neurons; An "excitatory" neurotransmitter. Norepinephrine is called "stress hormone".
Baidu encyclopedia-nicotine (nicotine)
Baidu encyclopedia-tobacco
Baidu Encyclopedia-How harmful is smoke to human body?