environmental pollution
There is an "environmental hormone", also known as "hormone-like" and "endocrine disruptor", which is a chemical substance with estrogen-like characteristics that exists in the environment. After they enter the human body, they will act on many aspects of sperm development, leading to abnormal sperm development, decreased quantity and quality of male sperm, greatly reduced pregnancy rate of women, and even completely lost fertility. It can be said that environmental pollution is the first killer of sperm. It poses a greater threat to human beings: it is latent, persistent and irreversible, and it is difficult for people to detect its harm in a short time (years or longer).
Smoking and drinking
Nicotine in cigarettes will kill sperm, cause sperm dysplasia, increase the proportion of deformed and defective sperm, and even make sperm chromosomes mutate suddenly, leading to genetic changes. Alcohol has a strong toxic effect on germ cells, which will damage sperm and affect embryo development. Long-term drinking will reduce male fertility. Studies have proved that alcohol can slow down the synthesis of testosterone, affect the normal metabolism of testosterone, lead to hypogonadism, and affect sperm production and semen quality.
Eating disorders
The production of sperm needs the supply of nutrients, and malnutrition or imbalance directly affects the production of sperm. Cholesterol, arginine and zinc in nutrition are most closely related to fertility. Cholesterol is an important raw material for synthesizing sex hormones; Arginine is an essential component of sperm formation; Zinc is an important trace element in human body, and the content of zinc in semen is nearly 100 times higher than that in plasma. Zinc directly participates in glycolysis and oxidation in sperm, maintains the integrity and permeability of sperm cell membrane, and maintains sperm vitality. Zinc deficiency can lead to testicular atrophy, decreased sperm count, sexual dysfunction, and even loss of fertility in severe cases.
high fever
Spermatogenesis requires a lower temperature. Sperm can only be produced smoothly if the testis is in the scrotum with a temperature lower than body temperature. For example, the testicles of cryptorchidism patients are not in the scrotum, but in other parts of the body 2~3 degrees Celsius higher than the scrotum for a long time, which makes the spermatogenic cells irreversibly damaged and unable to produce sperm. Therefore, any clothes, living habits and environment that make the temperature of genital parts too high may reduce the number of sperm, affect pregnancy and even lead to infertility. For example, I am used to taking a bath with overheated water, often taking a sauna and often wearing tight jeans with curves. It is even worse for male infertility.
Negative drug
Antitumor drugs such as cyclophosphamide, vincristine, colchicine for gout and tripterygium wilfordii for rheumatoid arthritis can cause sperm growth disorders. Monoamine oxidase inhibitors, antihypertensive drugs, aspirin, ketoconazole, gossypol, etc. Will affect the production of sperm. Preservatives and hydrogen peroxide in food have certain toxic effects on sperm. The antiepileptic drug phenytoin sodium can inhibit the secretion of gonadotropin by pituitary gland and indirectly affect sperm production. Testosterone can inhibit hypothalamic function and spermatogenesis.
radiation
Spermatogenic cells are very sensitive to radiation. If directly irradiated with radiation, the number of spermatogenic cells will gradually decrease. However, the degree of this damage is related to the intensity of radiation and the length of irradiation time: the radiation intensity is weak, and the damage caused in a short time is light, and the damage may be temporary, which can restore fertility; But if the radiation intensity is too strong or the time is too long, it may cause irreversible infertility. Long-term exposure to radiation, such as radiologists and nuclear workers. It can inhibit sperm production and cause sperm chromosome aberration.
be down in spirits
The so-called energy refers to a person's mental state. Energy shows that sperm is also related. If the sperm quality is not good, there may be some reasons for men to have mental illness. There are many reasons for men's mental depression, such as: heavy work pressure, frequent fatigue, irregular life and poor mental state. These nervous and anxious emotions can directly affect the nervous system and endocrine function, making testicular spermatogenesis disorder.