Experts explain why it is important to relax the age of nine-valent vaccination for cervical cancer vaccination.

The vaccination target of the nine-valent HPV vaccine was changed from the original 16-26 years old to 9-45 years old. This expansion will undoubtedly greatly expand the market of the nine-valent HPV vaccine, and more people will play the nine-valent vaccine. Why is the age of nine-valent vaccination relaxed? How important is cervical cancer vaccination? Let me introduce you.

Experts explain why the vaccination age of nine-valent vaccine is relaxed. In this regard, Qiao, a professor at the School of Group Medicine and Public Health of Peking Union Medical College, China Academy of Medical Sciences, said: "Adolescent girls inoculated with HPV vaccine can easily stimulate a better immune response. Women who have not had sex with human papillomavirus will get the best preventive effect. "

Andrea Carvalho, a senior scientist at the International Agency for Research on Cancer of the World Health Organization, delivered a speech on "Global Strategy for Accelerating the Elimination of Cervical Cancer" at a global health summit held by the 2022 Pujiang Innovation Forum on August 28th, and optimistically predicted that China would be able to completely eliminate cervical cancer from 2046 to 2050 after implementing the correct prevention and control strategies for cervical cancer.

The nine-valent vaccine has the same protective effect on women aged 65,438+06-26 as the four-valent vaccine of 6/65,438+06/65,438+08. The remaining HPV3 1/33/45/52/58 can protect 97. 1% and CIN+ 100%. Nine-valence protection is only a little better than two-valence and four-valence. If you have already injected bivalent or tetravalent, it is not recommended to inject ninevalent again.

Of course, if an appointment is made and the economy permits, it is recommended to inject again at intervals of 12 months or more.

How important is cervical cancer vaccination? WHO suggests that the sexless women aged 9~ 14 should be the main target population for human papillomavirus vaccination.

84.5% of cervical cancer is caused by persistent infection of high-risk HPV 16/ 18. Cervical cancer is the main "killer" that threatens women's health, and it is the only cancer with clear etiology and prevention and control at present.

Because the existing cervical cancer vaccine (HPV vaccine) is a preventive vaccine, it can only effectively prevent the infection that has not yet occurred, but can not eliminate the existing infection or treat the human papillomavirus-related diseases. The earlier and smaller, the better the inoculation effect. Vaccination with HPV vaccine before the first sexual intercourse can block the spread of human papillomavirus as much as possible.

At present, there are bivalent, tetravalent and nonavalent human papillomavirus vaccines in China. Can prevent 90% of cervical cancer. Moreover, the protective effect of three doses of bivalent and tetravalent HPV vaccine can last for 9 ~ 10 years; Three doses of nine-valent HPV vaccine were inoculated, and the protective effect lasted for 6 years.

Bivalent and tetravalent human papillomavirus vaccines can be vaccinated from the age of 9. Bivalent, tetravalent and nonavalent human papillomavirus vaccines can provide the same immunogenicity and protective efficacy in preventing HPV 16/ 18-related cervical cancer.