Chronic urticaria has complex etiology, unclear pathogenesis, difficult treatment and long course of treatment. Correct treatment needs to do the following:
1. Find the reason
Ask the medical history in detail, try to find out the cause of each patient's illness, whether there is a family disease, whether there is a history of acute and chronic infection, medication history, occupation, living habits, environmental changes, etc. Routine examination of blood, urine and stool, skin allergen examination, ice test, acetylcholine skin test, serum IgE determination and serum complement determination if necessary. Individual patients should be tested for HBV-DNA, thyroid antibody and malignant tumor.
2. Avoid inducing factors
Cold urticaria pays attention to keeping warm, acetylcholine urticaria reduces exercise, sweating and mood swings, and contact urticaria reduces contact opportunities.
Step 3 Use antihistamines
Most patients can get satisfactory curative effect after antihistamine treatment, and a few patients are stubborn. For intractable urticaria, the dosage can be increased or combined with medication. H 1 receptor antagonists have strong antihistamines and other inflammatory mediators, and are effective in treating various urticaria. Commonly used H 1 receptor antagonists include diphenhydramine, cyproheptadine, chlorphenamine, Avastin, cetirizine, mizolastine, loratadine, ebastine, azelastine and desloratadine. Two different types of H 1 receptor antagonists can be used together or in combination with H2 receptor antagonists (cimetidine and ranitidine). Antaile has strong antihistamine, anticholinergic and sedative effects, and also has good antipruritic effect. It is effective for acute and chronic urticaria and cold urticaria. Doxepin is a tricyclic antidepressant, which is mainly used to treat depression and anxiety. This drug also has strong resistance to H 1 and H2 receptors. It is especially effective for chronic urticaria with few side effects. Doxepin is a better choice for urticaria patients whose traditional antihistamines are ineffective.
4. Choose drugs that can inhibit degranulation of mast cells.
Ketothiol can inhibit mast cell degranulation and prevent the release of inflammatory mediators by increasing the concentration of cAMP in vivo. Its inhibitory effect is stronger and faster than that of sodium cromoglycate, and it can be taken orally. Tranilast reduces histamine release by stabilizing mast cell membrane.
5. glucocorticoid
It has strong anti-inflammatory and anti-allergic effects. It can stabilize mast cell membrane and lysosomal membrane and inhibit the release of inflammatory mediators and lysosomal enzymes; Contraction of blood vessels, reducing exudation. Has good curative effect on urticaria, and is especially suitable for acute urticaria's disease, serum urticaria, stress urticaria and autoimmune urticaria. Commonly used drugs are prednisone and diprospan. In case of emergency, hydrocortisone, dexamethasone or methylprednisolone should be used for intravenous drip.
6. Immunosuppressants
Patients with chronic urticaria have an autoimmune basis. When the condition is repeated, immunosuppressants can be used when the above treatment fails to achieve the curative effect. Cyclosporine is effective, azathioprine, cyclophosphamide, methotrexate and immunoglobulin can all be tried, and tripterygium wilfordii has a certain effect.
7. Nonspecific antiallergic therapy and other therapies
Try 10% calcium gluconate injection, 10% sodium thiosulfate, 6- aminocaproic acid, reserpine, aminophylline and other drugs.
8. Handling of special circumstances
Urticaria caused by infection should be treated with anti-infective drugs. For cold urticaria, cyproheptadine, doxepin, ketotifen, hydroxyzine and mizolastine are the best antihistamines. Vitamin E, cinnarizine and H2 receptor antagonists can be used in combination. Azatadine has a good effect on cold urticaria through its antihistamine, anticholine and serotonin. For solar urticaria, hydroxychloroquine, thalidomide or perchloric acid can be taken in addition to the antihistamine hydroxyzine or chlorpheniramine.
The above is the general treatment. You usually take chlorpheniramine if you have an injection. Or take loratadine. There is no cure. The patient will be in pain. If you want a popular treatment, you should pay more attention to exercise, because poor health and poor immunity can also lead to. Then pay more attention to diet.
Question 2: I have chronic urticaria, which recurs as soon as I stop taking the medicine. Excuse me, kind netizens, what are the effective treatments or effective remedies? Common treatments for urticaria are as follows:
Cupping navel: I often had urticaria when I was a child. Later, it was introduced that cupping navel can be treated. My mother tried it for me, and cupping was buckled on my navel. It was cured after two or three times, and there was no more illness.
Urticaria can't be cured for a long time. The old Chinese doctor prescribed a prescription: 500 grams of Chinese cabbage, wash the sediment, drain the water, and rub 3- 15 trees on the affected area every time to cool off the heat. Every morning and evening 1 time, only recovered for 3 times, and there is no recurrence so far.
Prescription for children with urticaria: 5 cicadas in the pond and 250g duckweed, decocted in water twice a day (once in the morning and once in the evening).
Raw sesame 180g. Mash it, put it in a thin cloth bag and rub the affected area frequently. Take a proper amount of fresh peach leaves and rub the affected area repeatedly until it is healed.
30 grams of Patrinia scabra, decocted in water, 2-3 times a day.
Xu Changqing 60g, Cynanchum atratum15g. Decoct with water and wash the affected area. 2-3 times a day.
30 grams of poplar bark and 6 grams of alum are decocted in water and washed on the affected area. 2-3 times a day.
30g of Xanthium sibiricum, 30g of duckweed and 30g of Platycladus orientalis leaves, decocted in water, daily 1 dose, taken twice.
Gypsum, Kochia scoparia each 30g, Anemarrhena asphodeloides, Bombyx Batryticatus, japonica rice each 9g, licorice root 3g. Decoct with water, daily 1 dose, twice.
Kochia scoparia 100g, decocted twice with water, and the mixed solution was concentrated to 400 ml. Adults should take 1 dose twice a day, and children should reduce it as appropriate. At the same time, wrap the residue with gauze and rub it on the affected area while it is hot. Three days is 1 course of treatment.
Kochia scoparia and Polygonum multiflorum Thunb. 30g each, motherwort15g, Schizonepeta tenuifolia and Saposhnikovia divaricata10g. Decoct with water, daily 1 dose, twice, and add brown sugar 15g each time. Take hot clothes to shelter from the wind and bring some sweat.
20g of duckweed, 20g of divaricate Saposhnikovia root and 20g of cicada slough, 0g of Dictamni bark15g, 0g of flaxseed15g and 0g of licorice root10g. Soak in water15min and boil for 20min. Daily 1 dose, taken twice. Used for intractable urticaria.
Chinese medicine experts believe that urticaria can only be effective if it is treated according to syndrome differentiation and the right medicine, that is, detailed treatment according to the clinical manifestations and symptoms of patients. Therefore, choosing a regular medical institution is the key.
Party 1
Prepare 20-30ml vinegar.
Usage: Take a bath with 5000 ml of water.
Indications: Chronic urticaria.
Fang 2
Comprise 20g of ginger, 0g of radix Saposhnikoviae10g, 0g of cassia twig10g and 2g of onion.
Usage: decoction, daily 1 dose.
Indications: wind-cold urticaria, characterized by itchy skin, light rash, pale tongue with thin coating and weak pulse after encountering wind or cold.
Fang 3
It consists of 150g leek, 50g scallion and 30ml white wine.
Usage: decoct in water twice a day.
Indications: urticaria.
Fang 4
It consists of 100ml rice vinegar, 60g papaya and 9g ginger.
Usage] When the casserole is boiled until the vinegar is dry, take out papaya and ginger and eat them twice in the morning and evening. Every day 1 dose, 7 ~1dose continuously.
Indications: wind-cold urticaria.
Fang 5
It consists of 30 grams of honey and 60 ml of yellow wine.
Usage: stew evenly, take it on an empty stomach, daily 1 dose, and the cure is degree.
Indications: wind-cold urticaria.
Fang 6
It consists of 250g wheat bran and 500ml vinegar.
Usage: Mix the medicines evenly, stir-fry them in an iron pan, put them in a cloth bag and rub the affected area.
Indications: wind-cold urticaria.
Fang 7
Garlic (minced) 15g, salt 15g, alum 12g.
Decoct with water and apply hot compress to the affected area.
Indications of urticaria
Fang 8
It consists of Stemona Stemona 15g and Chinese liquor 100ml.
Usage: Rub the affected area externally after cooking.
Indications: urticaria. ...& gt& gt
Question 3: Got acute urticaria, took medicine, and then relapsed. Hello, I have had urticaria before, and I really want to die. It took more than a year, and it was cured later. My method is to add vitamin C to calcium tablets. Eating this has no side effects on your health, but don't eat too much. Just take one tablet at the same time every day. . . If it really doesn't work, try Chinese medicine. This will also take effect soon. What you should pay attention to is that you must not eat spicy food such as peppers, and pay attention to your diet. It will be all right soon. My very best wishes to your health
Question 4: Urticaria or recurrent chronic urticaria after taking medicine for three months is a common dermatological disease, which is difficult to cure and mainly related to allergies. It is suggested that you can go to the hospital to check allergens and see if you can investigate some suspicious allergens and stay away from them, which will effectively reduce recurrence and avoid spicy food.