Symptoms of neurofibroma 1. Skin symptoms: The patients have milky brown macules with different sizes and clear edges, which gradually become larger with age, and the color changes from light to dark, and the number increases. They are prone to occur in non-exposed parts of the trunk, with different shapes and sizes, irregular edges and no higher than the skin surface.
2. Nervous system symptoms: Some patients may be accompanied by nervous system diseases, mainly caused by tumor compression, manifested as mental retardation, memory disorder and seizures, which may be combined with spinal deformity, myelocele and syringomyelia, leading to changes in normal physiological curvature of the spine and spinal pain.
3. Eye symptoms: The patient may present as fibrochondroma of the upper eyelid, orbital mass, exophthalmos, grayish white tumor of fundus and galactorrhea.
Patients with head protrusion and optic glioma may also have exophthalmos and decreased vision.
4. Tumor symptoms: The patient may suffer from various benign and malignant tumors, such as optic nerve glioma and cutaneous neurofibromatosis. , distributed in the trunk, limbs and other parts. There is no pain, but there may be pain in the superficial nerve.
5. Plexus neurofibroma: it is a neurofibroma of two or more skins, or a plexiform neurofibroma of the skin, which is characterized by thickening of the skin surface and deepening of pigment.
6. Visceral symptoms: neurofibromas growing in the chest, mediastinum, abdominal cavity or pelvic cavity can cause visceral symptoms, in which gastrointestinal tract involvement can cause gastrointestinal bleeding or obstruction, and can also cause endocrine abnormalities.
The classification of neurofibroma is 1, and neurofibroma is 1.
Neurofibroma 1 is a typical common neurofibroma, and patients often show painless nodules under the skin, accompanied by milk coffee spots. The patient's iris may also have yellowish nodules, but generally it will not bring discomfort to the patient. Only a few patients with neurofibroma 1 have symptoms of skin pain or decreased intelligence and memory.
2, neurofibroma type 2
Neurofibroma type 2 is much more serious than type 1. On the one hand, this neurofibroma will produce bilateral acoustic neuromas, leading to obvious tinnitus, and finally it will gradually evolve into hearing loss, which is very harmful to the health and quality of life of patients. On the other hand, once the type 2 neurofibroma grows in the patient's brain, it will oppress the nerves in the patient's brain with the gradual growth of the tumor, which will increase the intracranial pressure of the patient, cause nausea, headache, vomiting and other symptoms, and may also cause grand mal. In severe cases, patients may lose consciousness, coma and shock, which is very dangerous.
The difference between coffee spot and neurofibroma is 1. The causes are different: neurofibroma is a chromosomal dominant genetic disease, which is caused by gene mutation, ectopic and other defects. The incidence rate is very low, about 1/3000~ 1/4000, which can be divided into 1 type and type 2 neurofibromatosis. However, coffee spots are mostly caused by genetic factors and belong to congenital skin diseases.
2. Different clinical manifestations: neurofibroma is mainly a kind of tumor protruding from the skin, which is mostly distributed in superficial parts such as dermis or subcutaneous, and can also be distributed in any part such as internal organs and nervous system. It is a non-toxic nodule or mass with slow growth and different sizes, and some tumors have unclear boundaries. However, coffee spots are mainly pigmentation that does not highlight the skin, usually light brown, brown to dark brown spots with smooth surface, different shapes and numbers.
3. Different treatment methods: At present, neurofibroma is mainly removed by surgery. This disease cannot be completely cured, mainly by relieving symptoms and inhibiting the development of the disease.