Through long-term contact with various pig farms, the author found that respiratory diseases are mostly mixed infections, among which the main diseases are blue ear disease, circovirus II, infectious pleuropneumonia and mycoplasma pneumonia (asthma), among which blue ear disease is the core factor. There are many serotypes of blue ear disease. Although the symptoms of simple blue ear disease are not very serious and the mortality rate is not very high, the persistent infection of blue ear disease will cause immunosuppression, which will lead to secondary infection of other diseases and bring very serious consequences. For example, blue ear disease is like the boss of the underworld, and other germs are equivalent to his henchmen. Underworld bosses generally don't cut people directly, but it's harmful for the boss to gather a group of henchmen. If you want to eliminate the damage, it is useless to deal with only a few enemies. As long as the black boss is here, many enemies will gather again soon. So, if you want to get rid of the black boss, the messenger will naturally disappear. Therefore, to control respiratory diseases in pig farms, we must first effectively control blue ear disease.
Immunosuppression is the key factor of recurrent respiratory diseases. Porcine blue ear disease and circovirus can cause immunosuppression in pigs, resulting in decreased immune function and lack of immune response. Vaccine immunization can not produce enough antibodies or produce antibodies slowly, and when the antibody level is low, it can not resist viral diseases such as classical swine fever and pseudorabies. On the other hand, the body's overall resistance is poor, causing the incidence of conditional pathogens, such as mycoplasma, Pasteurella, Streptococcus, Haemophilus parasuis and so on. In addition, mold is also a factor that can not be ignored in causing immunosuppression.
The prevention and control of respiratory diseases should start with systematic prevention and control, and antibiotics alone cannot solve respiratory problems. It should be carried out systematically from the aspects of feeding management, environmental control, vaccine epidemic prevention and drug prevention. The principle of prevention and control is to eliminate immunosuppression and control blue ear disease, followed by controlling various bacterial diseases.
First of all, feed nutrition and mycotoxins should be controlled, the environment should be "pig-oriented", and appropriate temperature, humidity, density and ventilation should be controlled. Ventilation and temperature in winter are long-standing contradictions in most places, so it is necessary to keep pace with the times and improve breeding equipment. In terms of vaccine epidemic prevention, it is necessary to formulate standardized epidemic prevention procedures, and do not arbitrarily change the immunization time and vaccine varieties. In drug prevention, immune enhancers, heat-clearing, detoxicating and antiviral Chinese medicines should be used appropriately, and appropriate antibiotics should be added according to clinical symptoms and major epidemic diseases.
Many farmers know that tilmicosin can purify blue ear disease. Is it true?/You don't say. There are two main mechanisms: first, many studies show that tilmicosin can promote the differentiation and proliferation of macrophages in vivo, increase the number of macrophages, improve the ability and efficiency of removing infectious pathogens in vivo, and significantly improve the immunity of the body; Secondly, the replication of blue-ear viruses and macrophages requires an acidic environment. After being taken orally by animals, tilmicosin can be distributed in the lungs of animals and aggregated in macrophages to form a high concentration. However, the physical and chemical properties of tilmicosin are alkaline, and a large number of tilmicosin accumulates in macrophages, which makes the environment in macrophages weakly alkaline, and finally the virus that invades macrophages loses the necessary conditions for replication and reproduction. Scientific use of tilmicosin can enhance the overall ability to resist external stress or seasonal epidemic, and the incidence or secondary infection is significantly reduced. Xu Qun's overall sanitary water quality and data monitoring are good.
Many farmers will not choose tilmicosin when they buy it. As we all know in the industry, since 20 17, the environmental protection requirements of the state for veterinary drug enterprises have been upgraded, which has caused many raw material factories and veterinary drug factories to limit production, and the prices of tilmicosin, florfenicol, doxycycline and other veterinary drugs have soared. Therefore, the price of 20% tilmicosin with better technology is higher than that of 350 yuan. The technology of tilmicosin is very important, because tilmicosin itself is bitter, which directly leads to anorexia in pigs, and the feed intake is greatly reduced, which can not achieve good results. At present, there is a coating process in the market, but the rough coating process leads to large particles and uneven mixing. Tilmicosin coated with superfine capsules is very delicate and has no bitterness, which greatly improves the feed intake of pigs and enhances the effect. In addition, the coated tilmicosin also has a sustained release effect, which can make the drug act in the body for a longer time.
In view of the common and serious respiratory diseases in pig farms in autumn and winter, the author recommends a scheme: tilmicosin+florfenicol+doxycycline. After clinical experiments, the effect is excellent. The author's idea of treating respiratory diseases is that the dosage should be sufficient and the time should be enough (at least 7 days), so that the treatment can be more thorough and difficult to repeat.